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Genetic reprogramming of tumor cells by zinc finger transcription factors

Genetic reprogramming of tumor cells by zinc finger transcription factors

http://www.wikidata.org/entity/Q33221141

about

Targeting serous epithelial ovarian cancer with designer zinc finger transcription factors Utrophin up-regulation by an artificial transcription factor in transgenic mice Induction of stable drug resistance in human breast cancer cells using a combinatorial zinc finger transcription factor library Profiling the DNA-binding specificities of engineered Cys2His2 zinc finger domains using a rapid cell-based method Tailor-made zinc-finger transcription factors activate FLO11 gene expression with phenotypic consequences in the yeast Saccharomyces cerevisiae.Tra1 as a screening target for transcriptional activation domain discovery.Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays Modular system for the construction of zinc-finger libraries and proteins.Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies.A synthetic biology framework for programming eukaryotic transcription functions.Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers.Enhanced MyoD-induced transdifferentiation to a myogenic lineage by fusion to a potent transactivation domain Targeting the absence: homozygous DNA deletions as immutable signposts for cancer therapy.Chimeric piggyBac transposases for genomic targeting in human cells Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer Systematic identification of transcription factors associated with patient survival in cancers.The pan-cancer pathological regulatory landscape Speed-stability paradox in DNA-scanning by zinc-finger proteins.Randomized CRISPR-Cas Transcriptional Perturbation Screening Reveals Protective Genes against Alpha-Synuclein Toxicity.Reprogramming cell fate with artificial transcription factors.

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Genetic reprogramming of tumor cells by zinc finger transcription factors

http://www.wikidata.org/entity/Q33221141

description

2005 nî lūn-bûn

@nan

2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2005年の論文

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2005年論文

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2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Genetic reprogramming of tumor cells by zinc finger transcription factors

@ast

Genetic reprogramming of tumor cells by zinc finger transcription factors

@en

type

label

Genetic reprogramming of tumor cells by zinc finger transcription factors

@ast

Genetic reprogramming of tumor cells by zinc finger transcription factors

@en

prefLabel

Genetic reprogramming of tumor cells by zinc finger transcription factors

@ast

Genetic reprogramming of tumor cells by zinc finger transcription factors

@en

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PNAS.0501162102

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Genetic reprogramming of tumor cells by zinc finger transcription factors

@en

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Arndt Brachat

http://www.w3.org/2001/XMLSchema#string

Carlos F Barbas

http://www.w3.org/2001/XMLSchema#string

Daniel Guthy

http://www.w3.org/2001/XMLSchema#string

Dirk Erdmann

http://www.w3.org/2001/XMLSchema#string

Emily I Chen

http://www.w3.org/2001/XMLSchema#string

James P Quigley

http://www.w3.org/2001/XMLSchema#string

Ruud H Brakenhoff

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Sharon Bergquist

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P2860

The human E48 antigen, highly homologous to the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion

CD157 is an important mediator of neutrophil adhesion and migration

Characterization of IL-4 and IL-13 signals dependent on the human IL-13 receptor alpha chain 1: redundancy of requirement of tyrosine residue for STAT3 activation

Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide

A molecular signature of metastasis in primary solid tumors

Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression

Scanning the human genome with combinatorial transcription factor libraries.

Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains.

In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation.

Promoter-targeted phage display selections with preassembled synthetic zinc finger libraries for endogenous gene regulation.

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11716-11721

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scholarly article

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10.1073/PNAS.0501162102

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33

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102

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Beatriz Gonzalez

Andries Zijlstra

Pilar Blancafort

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2005-08-04T00:00:00Z

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7677629

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16081541

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1187960

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