A role for kinesin in insulin-stimulated GLUT4 glucose transporter translocation in 3T3-L1 adipocytes.
about
The novel protein KBP regulates mitochondria localization by interaction with a kinesin-like proteinCalpain facilitates GLUT4 vesicle translocation during insulin-stimulated glucose uptake in adipocytesRole that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysisInsulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesinSites of glucose transporter-4 vesicle fusion with the plasma membrane correlate spatially with microtubulesInsulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane rufflesInsulin stimulates movement of sorting nexin 9 between cellular compartments: a putative role mediating cell surface receptor expression and insulin actionGlucose transporter recycling in response to insulin is facilitated by myosin Myo1cRole of insulin-dependent cortical fodrin/spectrin remodeling in glucose transporter 4 translocation in rat adipocytesCortactin, an actin binding protein, regulates GLUT4 translocation via actin filament remodelingFocal Adhesion Kinase contributes to insulin-induced actin reorganization into a mesh harboring Glucose transporter-4 in insulin resistant skeletal muscle cellsThe GLUT4 codeDose and chemical modification considerations for continuous cyclic AMP analog delivery to the injured CNSNexilin, a cardiomyopathy-associated F-actin binding protein, binds and regulates IRS1 signaling in skeletal muscle cells.The role of glycogen synthase kinase-3 in insulin resistance and type 2 diabetes.Conventional kinesin KIF5B mediates insulin-stimulated GLUT4 movements on microtubulesGLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomesRegulation of glucose transport by ROCK1 differs from that of ROCK2 and is controlled by actin polymerizationMUNC-ing around with insulin action.The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocationTargeting glycogen synthase kinase-3 in insulin signalling.Disruption of cortical actin in skeletal muscle demonstrates an essential role of the cytoskeleton in glucose transporter 4 translocation in insulin-sensitive tissues.Loss of cortical actin filaments in insulin-resistant skeletal muscle cells impairs GLUT4 vesicle trafficking and glucose transport.Stimulation of glucose transport in response to activation of distinct AMPK signaling pathwaysSeparation of insulin signaling into distinct GLUT4 translocation and activation steps.The CLASP2 Protein Interaction Network in Adipocytes Links CLIP2 to AGAP3, CLASP2 to G2L1, MARK2, and SOGA1, and Identifies SOGA1 as a Microtubule-Associated Protein.Myosin motor Myo1c and its receptor NEMO/IKK-gamma promote TNF-alpha-induced serine307 phosphorylation of IRS-1.Insulin stimulates actin comet tails on intracellular GLUT4-containing compartments in differentiated 3T3L1 adipocytes.Disruption of microtubules ablates the specificity of insulin signaling to GLUT4 translocation in 3T3-L1 adipocytes.Microtubule network is required for insulin signaling through activation of Akt/protein kinase B: evidence that insulin stimulates vesicle docking/fusion but not intracellular mobility.Nocodazole inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes via a microtubule-independent mechanism.Naproxen and cromolyn as new glycogen synthase kinase 3β inhibitors for amelioration of diabetes and obesity: an investigation by docking simulation and subsequent in vitro/in vivo biochemical evaluation.A pre-docking role for microtubules in insulin-stimulated glucose transporter 4 translocation.PYK2 as a mediator of endothelin-1/G alpha 11 signaling to GLUT4 glucose transporters.Insulin-stimulated GLUT4 translocation in adipocytes is dependent upon cortical actin remodeling.Intracellular delivery of phosphatidylinositol (3,4,5)-trisphosphate causes incorporation of glucose transporter 4 into the plasma membrane of muscle and fat cells without increasing glucose uptake.Phosphatidylinositol 4,5-bisphosphate regulates adipocyte actin dynamics and GLUT4 vesicle recycling.A phosphatidylinositol 3-kinase-independent insulin signaling pathway to N-WASP/Arp2/3/F-actin required for GLUT4 glucose transporter recycling.High glucose and insulin promote O-GlcNAc modification of proteins, including alpha-tubulin.Disruption of microtubules in rat skeletal muscle does not inhibit insulin- or contraction-stimulated glucose transport.
P2860
Q21284166-6CADE50F-C9F0-4E41-B141-F3F717BB702BQ24322954-521D64C4-9AF5-4DBC-9739-D565A865B149Q24529125-88A3CD78-37BC-4EB7-964D-80F28607CF93Q24679721-F09B496A-D06D-4E33-A482-00B3A7B662B1Q27322797-D27F16CC-9F69-4827-8A51-4C66EE25431DQ28345581-A3B3EAF1-B16E-4ED7-A614-AD642E506164Q28508182-C37D6F77-E165-45B6-9DB9-7F0588D322A2Q28512823-61C5DEF8-8424-4974-962F-4EC7B0AAFB1AQ28574080-F35C769B-0E0C-4AA8-A791-574880FB11D8Q30010195-7C64FB9F-2045-4371-848D-910F9F421699Q33366859-C5C86689-4A5D-4796-89B4-C18E4BD7B16AQ33643340-6A013930-0CCA-47D4-BCDB-DDCCF8DCAA81Q33766778-165374EB-CBF3-4235-9FDD-D6B4A921BFD9Q34576839-D7C0CA02-FD49-45DF-919C-C53B6CE36815Q34974764-8095ED48-87B0-4E8D-8D09-815EC8D8BCD8Q35016947-F87C2FE1-009A-4FBC-9B26-0D87717DB949Q35803004-6FC6D22E-8529-41A1-9933-FD74B01DAC2AQ35872786-3E0C9A25-F199-417C-8961-2C3F71F01316Q36029223-9B70A9DA-FC5D-470C-ABEA-E246BDEB580FQ36137822-B05001C4-FCD9-4CA4-AE57-6FDA3F86F867Q36481069-13C1F3D7-CCAE-437A-B916-320A47CED58FQ36692823-5D2C0D22-1133-4250-9660-CE2F728360DAQ36713749-A3E73D3E-102E-4F4B-9AA4-CF23277CA485Q36977695-4C57F3BB-0D7C-4596-92D5-CECEDB310F41Q37349880-635B9CD0-1EAB-4E78-8C2F-0A8701A7C0E7Q38760699-06EC887A-8542-4766-B064-E4D12E943A81Q39729795-975598DA-5CA6-4DB9-B923-86362D9E8172Q40773886-73F8C715-F52B-4F6F-9678-4A0939124B7CQ42485575-1B384D44-F173-4058-A00D-5D9C32B90485Q42503312-EB4D0789-0A70-4910-A576-7890C5992078Q42510573-D6BF85B7-6357-4A23-BF56-F14BF208BB79Q42710614-78142DCC-4A5B-4644-B443-B60A36CFA222Q42818253-21495974-3480-4C49-8BCB-F9898F604FB0Q42824648-88E474E8-7462-43AE-8A1B-496005A5F47FQ42825746-B45CD334-3542-4DD2-986B-BA165CDDDBB7Q42828593-2ECCFC8B-F592-403A-A880-1FB8152A1420Q42829230-D782AF16-B4FC-45DA-A22E-9A694E51D074Q43789244-99D49311-3A84-4595-812B-05F2207DAFFBQ44191960-230A9223-8762-44E6-9866-42DF9E7B8E35Q44440420-67943879-3678-4AB7-BB8C-D087ABE2022D
P2860
A role for kinesin in insulin-stimulated GLUT4 glucose transporter translocation in 3T3-L1 adipocytes.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A role for kinesin in insulin- ...... location in 3T3-L1 adipocytes.
@ast
A role for kinesin in insulin- ...... location in 3T3-L1 adipocytes.
@en
type
label
A role for kinesin in insulin- ...... location in 3T3-L1 adipocytes.
@ast
A role for kinesin in insulin- ...... location in 3T3-L1 adipocytes.
@en
prefLabel
A role for kinesin in insulin- ...... location in 3T3-L1 adipocytes.
@ast
A role for kinesin in insulin- ...... location in 3T3-L1 adipocytes.
@en
P2093
P2860
P356
P1476
A role for kinesin in insulin- ...... location in 3T3-L1 adipocytes.
@en
P2093
P2860
P304
10677-10682
P356
10.1074/JBC.M010785200
P407
P577
2001-01-05T00:00:00Z