Characterization of the Alkylation Product of Heme by the Antimalarial Drug Artemisinin We are grateful to the CNRS for financial support, and to the French Ministery of Education for a PhD grant to J.C. Dr. Yannick Coppel (LCC-CNRS) is gratefully a
about
Artemisinin-resistant malaria: research challenges, opportunities, and public health implicationsHaem-activated promiscuous targeting of artemisinin in Plasmodium falciparumThe antimalarial drug artemisinin alkylates heme in infected mice.Syntheses and biological studies of marine terpenoids derived from inorganic cyanide.Mechanisms of in situ activation for peroxidic antimalarials.Trioxaquines are new antimalarial agents active on all erythrocytic forms, including gametocytesThe therapeutic potential of semi-synthetic artemisinin and synthetic endoperoxide antimalarial agents.1,4-naphthoquinones and other NADPH-dependent glutathione reductase-catalyzed redox cyclers as antimalarial agentsCorrelation between Plasmodium yoelii nigeriensis susceptibility to artemisinin and alkylation of heme by the drug.Malaria and iron: history and review.The interaction of heme with plakortin and a synthetic endoperoxide analogue: new insights into the heme-activated antimalarial mechanism.Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs.Alkylation of manganese(II) tetraphenylporphyrin by a synthetic antimalarial trioxane.Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine.Alkylation of human hemoglobin A0 by the antimalarial drug artemisinin.Artemisinin and heme.Heme alkylation by artesunic acid and trioxaquine DU1301, two antimalarial trioxanes.Peroxide bond strength of antimalarial drugs containing an endoperoxide cycle. Relation with biological activity.Second generation analogues of RKA182: synthetic tetraoxanes with outstanding in vitro and in vivo antimalarial activities
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P2860
Characterization of the Alkylation Product of Heme by the Antimalarial Drug Artemisinin We are grateful to the CNRS for financial support, and to the French Ministery of Education for a PhD grant to J.C. Dr. Yannick Coppel (LCC-CNRS) is gratefully a
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Characterization of the Alkyla ...... pel (LCC-CNRS) is gratefully a
@ast
Characterization of the Alkyla ...... pel (LCC-CNRS) is gratefully a
@en
type
label
Characterization of the Alkyla ...... pel (LCC-CNRS) is gratefully a
@ast
Characterization of the Alkyla ...... pel (LCC-CNRS) is gratefully a
@en
prefLabel
Characterization of the Alkyla ...... pel (LCC-CNRS) is gratefully a
@ast
Characterization of the Alkyla ...... pel (LCC-CNRS) is gratefully a
@en
P2860
P1433
P1476
Characterization of the Alkyla ...... pel (LCC-CNRS) is gratefully a
@en
P2093
Anne Robert
Jérôme Cazelles
P2860
P304
P356
10.1002/1521-3773(20010518)40:10<1954::AID-ANIE1954>3.0.CO;2-9
P577
2001-05-01T00:00:00Z