The mechanism of action of steroidogenic acute regulatory protein (StAR). StAR acts on the outside of mitochondria to stimulate steroidogenesis. - Wikidata - wikimedia - TriplyDB

The mechanism of action of steroidogenic acute regulatory protein (StAR). StAR acts on the outside of mitochondria to stimulate steroidogenesis.

The mechanism of action of steroidogenic acute regulatory protein (StAR). StAR acts on the outside of mitochondria to stimulate steroidogenesis.

http://www.wikidata.org/entity/Q32060629

about

Intracellular cholesterol transport The active form of the steroidogenic acute regulatory protein, StAR, appears to be a molten globule Cholesterol transport and steroidogenesis by the corpus luteum Role of Protein Phosphorylation and Tyrosine Phosphatases in the Adrenal Regulation of Steroid Synthesis and Mitochondrial Function Multitasking in the mitochondrion by the ATP-dependent Lon protease Binding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterols Targeted mutation of the MLN64 START domain causes only modest alterations in cellular sterol metabolism Steroidogenic acute regulatory protein (StAR) is a sterol transfer protein Roundup inhibits steroidogenesis by disrupting steroidogenic acute regulatory (StAR) protein expression Molten-globule structure and membrane binding of the N-terminal protease-resistant domain (63-193) of the steroidogenic acute regulatory protein (StAR)ACTH-induced nucleocytoplasmic translocation of salt-inducible kinase. Implication in the protein kinase A-activated gene transcription in mouse adrenocortical tumor cells The proteasome inhibitor MG132 promotes accumulation of the steroidogenic acute regulatory protein (StAR) and steroidogenesis Functional characterization of the MENTAL domain.Steroidogenic acute regulatory protein (StAR) acts on the outside of mitochondria to stimulate steroidogenesis.Angiotensin II-induced protein kinase D activates the ATF/CREB family of transcription factors and promotes StAR mRNA expression.Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones.Steroidogenic acute regulatory protein-binding protein cloned by a yeast two-hybrid system.Differential gene regulation of StarD4 and StarD5 cholesterol transfer proteins. Activation of StarD4 by sterol regulatory element-binding protein-2 and StarD5 by endoplasmic reticulum stress.Altered zinc transport disrupts mitochondrial protein processing/import in fragile X-associated tremor/ataxia syndrome.Melatonin protects the integrity of granulosa cells by reducing oxidative stress in nuclei, mitochondria, and plasma membranes in mice.Convergence of 3',5'-cyclic adenosine 5'-monophosphate/protein kinase A and glycogen synthase kinase-3beta/beta-catenin signaling in corpus luteum progesterone synthesis.Angiotensin II-dependent transcriptional activation of human steroidogenic acute regulatory protein gene by a 25-kDa cAMP-responsive element modulator protein isoform and Yin Yang 1.Hormone-induced 14-3-3γ adaptor protein regulates steroidogenic acute regulatory protein activity and steroid biosynthesis in MA-10 Leydig cells Non-vesicular sterol transport in cells.Role of the steroidogenic acute regulatory protein in health and disease.Complex role of the mitochondrial targeting signal in the function of steroidogenic acute regulatory protein revealed by bacterial artificial chromosome transgenesis in vivo.SNARE-Mediated Cholesterol Movement to Mitochondria Supports Steroidogenesis in Rodent Cells.Regulation of the steroidogenic acute regulatory protein gene expression: present and future perspectives Thirty-Eight-Year Follow-Up of Two Sibling Lipoid Congenital Adrenal Hyperplasia Patients Due to Homozygous Steroidogenic Acute Regulatory (STARD1) Protein Mutation. Molecular Structure and Modeling of the STARD1 L275P Mutation.Epigenetics of endometriosis.Regulation of aldosterone synthesis and secretion.Mitochondrial cholesterol: mechanisms of import and effects on mitochondrial function.The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein.Transfer of cholesterol between phospholipid vesicles mediated by the steroidogenic acute regulatory protein (StAR).Metastatic lymph node 64 (MLN64), a gene overexpressed in breast cancers, is regulated by Sp/KLF transcription factors.The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis.Effects of Melatonin on Early Pregnancy in Mouse: Involving the Regulation of StAR, Cyp11a1, and Ihh Expression.The potential function of steroid sulphatase activity in steroid production and steroidogenic acute regulatory protein expression.Binding of steroidogenic acute regulatory protein to synthetic membranes suggests an active molten globule.Steroidogenic acute regulatory protein binds cholesterol and modulates mitochondrial membrane sterol domain dynamics.

P2860

Q24553317-DE05FDA4-4124-4838-AE7C-CA3F4C72D348 Q24648715-1DEA49DA-E033-4833-A108-CE3469880DDA Q24798689-485A1851-B9C6-46E3-A16E-293D8EAC3ABB Q26745112-079566A3-6D44-479E-8C9C-7B51A4344430 Q27003208-FC7B5E6E-E139-46BD-98CE-95AE52A45982 Q28241207-8F14AF68-DD61-4CC9-801F-CAFAC6496BF5 Q28245167-89B750B5-3F74-4B95-9CA6-4B9E5AB19627 Q28284056-D44FA67C-1390-41B7-97CA-9DBBFCAB083B Q28344702-7F962243-4FB0-4F3F-BD86-FFBD52A63F6B Q28364269-B9C5BC1D-D8DB-4778-96D1-2B027974B87B Q28509981-C8615EA7-B813-4AAB-B476-DCE8E6F62632 Q28580163-35B92B84-3805-4C03-88CF-CEA3152F343F Q30274633-CDD98368-B7E6-4B08-93A3-89B34E61AAF7 Q31934254-3492CE19-05BE-4CEA-B732-83B810850064 Q33765496-E3C6BF7F-36EF-4C47-AB3B-A25C5F63B969 Q33934310-E56C3416-C7FE-4E55-9732-F51D66D9BFB8 Q34221139-AAA921BD-F1BD-412C-A3A1-06E2B2913ABD Q34401927-4C0DCE92-5922-44AE-8FA6-8A7C6A3510A0 Q35090105-767B376F-66F3-4E3D-982F-541846E67CA7 Q35161015-F20C51D7-3514-4639-AD38-D7B6C8C47C13 Q35543017-9BCB19D9-54DA-4A01-B54F-F7F80BCEAFF9 Q35762734-3DB572F2-F28E-4414-9201-06CA9D6DB47C Q35939775-6D1294D9-5D98-417F-AE3C-9F0D6C555925 Q36145366-BDBD1486-182D-49BA-BC2D-233D8311A06A Q36447481-E67D095F-3E26-4353-8EC0-22647F42C457 Q36512421-AD2E392B-672C-45D9-B95C-91271A48E5DB Q36688121-097BF385-3B38-4907-8740-42BB28B88776 Q37179102-957EE9F2-BDD3-4C00-B25F-84C005AAC254 Q37424676-7FCAE8AA-444C-4F6A-ACDC-E7FF5F76CC52 Q37571067-772C7AB9-8DBA-4285-B9EB-276A57E0E9F1 Q38221449-B567ADF7-682F-4B67-94E3-C4C48D4DC358 Q38271508-938CD6BE-7A8C-4765-A8E9-4039C9DDB63D Q38307236-814518CC-A0D2-48E0-85AB-67ED58E849AA Q39536902-C4AC0B76-7596-4390-AD7B-FBB1055F0E31 Q40640337-06DD75D6-2463-4846-A1A8-EDFC46F9398C Q40817426-DA67202E-63C6-4F3E-9B11-7D4AE08C6DDE Q41573138-2CB579A1-C5AE-4990-AB66-0C34B854ECCC Q42142110-D2653409-63CF-4F0E-A18A-8AD7C8771A74 Q43560349-E3D90A10-30E3-48DD-8DF9-931D8BC63B34 Q43698965-35E7DD2F-FAA8-4907-AE47-E163EA5DA370

P2860

The mechanism of action of steroidogenic acute regulatory protein (StAR). StAR acts on the outside of mitochondria to stimulate steroidogenesis.

http://www.wikidata.org/entity/Q32060629

description

1998 nî lūn-bûn

@nan

1998 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հունիսին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

The mechanism of action of ste ...... to stimulate steroidogenesis.

@ast

The mechanism of action of ste ...... to stimulate steroidogenesis.

@en

type

label

The mechanism of action of ste ...... to stimulate steroidogenesis.

@ast

The mechanism of action of ste ...... to stimulate steroidogenesis.

@en

prefLabel

The mechanism of action of ste ...... to stimulate steroidogenesis.

@ast

The mechanism of action of ste ...... to stimulate steroidogenesis.

@en

P1433

Q32060629-3842E7F7-B60F-4B2F-999E-4DC822938295

P1476

Q32060629-43E36D2E-F213-40A1-BB0C-ADF2F98F1FD8

P2093

Q32060629-17ACAD06-3DE8-4AF7-A202-1D9BE46E1E7D

Q32060629-532DF6CB-8B49-4442-9C47-163D10AF9E35

Q32060629-6C5BBFEF-340A-407C-90D5-4503FB90DD56

Q32060629-7467B5DA-7CB0-4607-A9EC-AEF0D24E6D46

Q32060629-9108517D-3766-482A-B808-279E44B72F9F

Q32060629-9194F4AE-402A-4680-B77A-2222754CBF0C

Q32060629-E5F0BA97-B87F-4F53-ADFD-4A5EE190EF05

Q32060629-EF36B29C-4D2E-41C7-80F5-C5E90F366AB6

Q32060629-FF6AAAFD-12F0-4911-A311-224EAA8F3D4E

P2860

Q32060629-25747ED1-7C4E-4D2A-8FA3-37BA6A8813F0

Q32060629-2FA3764F-0A6D-467D-B379-DBDB7AC1E6A3

Q32060629-336D7AEF-5616-4328-8B02-B657732B5449

Q32060629-397CB192-2145-444E-B558-75720F768619

Q32060629-522D9AD4-3322-45AD-BEAD-283A86E8FBD0

Q32060629-560CB5D2-549E-4934-A349-CA3CC2250904

Q32060629-6C5D5B30-C8B0-48A2-9D40-780703744F03

Q32060629-72502C09-BF96-4E00-B39F-66423AF8A4C1

Q32060629-90D2F205-17F3-48C4-AF08-AAB0439CFD0F

Q32060629-9E471635-01D8-4B92-B02E-1993B6462C15

P304

Q32060629-FECCB5B9-51C8-4287-983D-EAE13E14A7D4

P31

Q32060629-4A909070-85E7-43D9-86D7-95128A76467A

P356

Q32060629-31115B8B-8691-4440-B3F0-4B700BCEA409

P407

Q32060629-5B06810C-7152-4D80-9F24-27BD9977E01A

P433

Q32060629-823D563F-03B6-4765-8F91-6E6E250CF282

P478

Q32060629-0CB6E33A-53B1-4049-981F-F2D622C09E26

P50

Q32060629-4BB0097A-A6DF-4F37-AB8D-0D713A4D2AD2

P577

Q32060629-EB3B22E8-61C2-4C8C-AC5D-13F2EE0DB67C

P5875

Q32060629-046B067A-12E7-439C-A27C-5FBEF3FCF810

P698

Q32060629-1E59C512-80FD-4857-988F-C9BCA4511EED

P921

Q32060629-FE1098F3-BC9E-420F-8DCE-90FAA8B1FE45

P356

JBC.273.26.16339

P1433

Journal of Biological Chemistry

P1476

The mechanism of action of ste ...... a to stimulate steroidogenesis

@en

P2093

D Pain

http://www.w3.org/2001/XMLSchema#string

F Arakane

http://www.w3.org/2001/XMLSchema#string

G L Gerton

http://www.w3.org/2001/XMLSchema#string

H Watari

http://www.w3.org/2001/XMLSchema#string

J A Foster

http://www.w3.org/2001/XMLSchema#string

J F Strauss

http://www.w3.org/2001/XMLSchema#string

M Lewis

http://www.w3.org/2001/XMLSchema#string

N B Sepuri

http://www.w3.org/2001/XMLSchema#string

S E Stayrook

http://www.w3.org/2001/XMLSchema#string

P2860

Human steroidogenic acute regulatory protein: functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13

Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis

Phosphorylation of steroidogenic acute regulatory protein (StAR) modulates its steroidogenic activity

Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia

Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C Leydig tumor cell line

Submitochondrial distribution of three key steroidogenic proteins (steroidogenic acute regulatory protein and cytochrome p450scc and 3beta-hydroxysteroid dehydrogenase isomerase enzymes) upon stimulation by intracellular calcium in adrenal glomerulo

Rho GTPases and signaling networks

Steroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: implications for the mechanism of StAR action.

Uptake of lipoproteins by in situ perfused rat ovaries: identification of binding sites for high density lipoproteins.

In vivo zippering of inner and outer mitochondrial membranes by a stable translocation intermediate.

P304

16339-16345

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.273.26.16339

http://www.w3.org/2001/XMLSchema#string

P407

P433

26

http://www.w3.org/2001/XMLSchema#string

P478

273

http://www.w3.org/2001/XMLSchema#string

P50

Caleb B. Kallen

P577

1998-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

13651282

http://www.w3.org/2001/XMLSchema#string

P698

9632696

http://www.w3.org/2001/XMLSchema#string

P921