Molecular cloning and expression of cDNA for human RNase H.
about
Purification of Saccharomyces cerevisiae RNase H(70) and identification of the corresponding gene.Human RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processingGene cloning and characterization of recombinant RNase HII from a hyperthermophilic archaeonProperties of cloned and expressed human RNase H1.The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides.Human RNase H1 activity is regulated by a unique redox switch formed between adjacent cysteines.An upstream open reading frame and the context of the two AUG codons affect the abundance of mitochondrial and nuclear RNase H1Human RNase H1 uses one tryptophan and two lysines to position the enzyme at the 3'-DNA/5'-RNA terminus of the heteroduplex substrate.Potential roles of antisense technology in cancer chemotherapy.Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs.Structural requirements at the catalytic site of the heteroduplex substrate for human RNase H1 catalysis.Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver functionIncreased efficacy of antileishmanial antisense phosphorothioate oligonucleotides in Leishmania amazonensis overexpressing ribonuclease HSelective inhibitory DNA aptamers of the human RNase H1Circularized synthetic oligodeoxynucleotides serve as promoterless RNA polymerase III templates for small RNA generation in human cells.Ribonuclease H attack of leukaemic fused transcripts AML1-MTG8 (ETO) by DNA/RNA chimeric hammerhead ribozymes.Influence of mismatched and bulged nucleotides on SNP-preferential RNase H cleavage of RNA-antisense gapmer heteroduplexes.Molecular Mechanisms of Antisense Oligonucleotides.Biologically active antisense phosphorothioate oligodeoxyribonucleotides: synthesis, characterization, and studies of 3'-terminal phosphorothioate monoester analogues.Investigating the structure of human RNase H1 by site-directed mutagenesis.Stage-specific expression of Caenorhabditis elegans ribonuclease H1 enzymes with different substrate specificities and bivalent cation requirements.Identification of the gene encoding a type 1 RNase H with an N-terminal double-stranded RNA binding domain from a psychrotrophic bacterium.
P2860
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P2860
Molecular cloning and expression of cDNA for human RNase H.
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Molecular cloning and expression of cDNA for human RNase H.
@ast
Molecular cloning and expression of cDNA for human RNase H.
@en
type
label
Molecular cloning and expression of cDNA for human RNase H.
@ast
Molecular cloning and expression of cDNA for human RNase H.
@en
prefLabel
Molecular cloning and expression of cDNA for human RNase H.
@ast
Molecular cloning and expression of cDNA for human RNase H.
@en
P2093
P356
P1433
P1476
Molecular cloning and expression of cDNA for human RNase H.
@en
P2093
P356
10.1089/OLI.1.1998.8.53
P577
1998-02-01T00:00:00Z