Phenotypic knockout of nerve growth factor in adult transgenic mice reveals severe deficits in basal forebrain cholinergic neurons, cell death in the spleen, and skeletal muscle dystrophy.
about
The low-affinity receptor for neurotrophins p75NTR plays a key role for satellite cell function in muscle repair acting via RhoAUsing animal models to determine the significance of complement activation in Alzheimer's diseaseNeurotrophic Factors and Their Potential Applications in Tissue Regeneration.Specific in vivo knockdown of protein function by intrabodiesImpairment of the nerve growth factor pathway driving amyloid accumulation in cholinergic neurons: the incipit of the Alzheimer's disease story?Neurotrophins and the immune systemAlzheimer amyloid beta inhibition of Eg5/kinesin 5 reduces neurotrophin and/or transmitter receptor function.Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic miceThe modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration.Cardiovascular actions of neurotrophinsSatellite cells and the muscle stem cell nicheIntranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic miceDissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling in NGF deficit-induced neurodegenerationNerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice.Intranasal "painless" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 miceAnti-nerve growth factor Ab abrogates macrophage-mediated HIV-1 infection and depletion of CD4+ T lymphocytes in hu-SCID miceThe recent understanding of the neurotrophin's role in skeletal muscle adaptationTime dynamics of protein complexes in the AD11 transgenic mouse model for Alzheimer's disease like pathology.TrkA gene ablation in basal forebrain results in dysfunction of the cholinergic circuitry.Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance.Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neuronsNGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease.Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat.Apoptosis and in vitro Alzheimer disease neuronal models.ProNGF Drives Localized and Cell Selective Parvalbumin Interneuron and Perineuronal Net Depletion in the Dentate Gyrus of Transgenic MiceImpaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary NeuronsThe chemokine CXCL12 mediates the anti-amyloidogenic action of painless human nerve growth factor.Evaluation of the Effects of Tanezumab, a Monoclonal Antibody Against Nerve Growth Factor, on the Sympathetic Nervous System in Adult Cynomolgus Monkeys (Macaca fascicularis): A Stereologic, Histomorphologic, and Cardiofunctional Assessment.Neuroprotection by Cocktails of Dietary Antioxidants under Conditions of Nerve Growth Factor DeprivationNicotine-induced enhancement of synaptic plasticity at CA3-CA1 synapses requires GABAergic interneurons in adult anti-NGF mice.Stem cell transplantation for enhancement of learning and memory in adult neurocognitive disorders.Efficacy of cyclin dependent kinase 4 inhibitors as potent neuroprotective agents against insults relevant to Alzheimer's disease.The use of phage display to generate conformation-sensor recombinant antibodies.Dissecting the role of sortilin receptor signaling in neurodegeneration induced by NGF deprivation.NGF steers microglia toward a neuroprotective phenotype.
P2860
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P2860
Phenotypic knockout of nerve growth factor in adult transgenic mice reveals severe deficits in basal forebrain cholinergic neurons, cell death in the spleen, and skeletal muscle dystrophy.
description
2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Phenotypic knockout of nerve g ...... and skeletal muscle dystrophy.
@ast
Phenotypic knockout of nerve g ...... and skeletal muscle dystrophy.
@en
type
label
Phenotypic knockout of nerve g ...... and skeletal muscle dystrophy.
@ast
Phenotypic knockout of nerve g ...... and skeletal muscle dystrophy.
@en
prefLabel
Phenotypic knockout of nerve g ...... and skeletal muscle dystrophy.
@ast
Phenotypic knockout of nerve g ...... and skeletal muscle dystrophy.
@en
P2093
P1476
Phenotypic knockout of nerve g ...... and skeletal muscle dystrophy
@en
P2093
A Cattaneo
A Comparini
E Di Daniel
S Gonfloni
P304
P356
10.1523/JNEUROSCI.20-07-02589.2000
P407
P577
2000-04-01T00:00:00Z