Specific binding of Hoechst 33258 to site 1 thymidylate synthase mRNA.
about
Studying a Drug-like, RNA-Focused Small Molecule Library Identifies Compounds That Inhibit RNA Toxicity in Myotonic DystrophyHoechst 33258 selectively inhibits group I intron self-splicing by affecting RNA folding.Activity of Hoechst 33258 against Pneumocystis carinii f. sp. muris, Candida albicans, and Candida dubliniensis.Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3.H-gemcitabine: a new gemcitabine prodrug for treating cancerDefining the RNA internal loops preferred by benzimidazole derivatives via 2D combinatorial screening and computational analysisMBNL proteins and their target RNAs, interaction and splicing regulation.A small molecule that targets r(CGG)(exp) and improves defects in fragile X-associated tremor ataxia syndrome.Identifying the preferred RNA motifs and chemotypes that interact by probing millions of combinations.Targeting a regulatory element in human thymidylate synthase mRNA.Translational repression of thymidylate synthase by targeting its mRNA.Rational selection of small molecules that increase transcription through the GAA repeats found in Friedreich's ataxia.Using modularly assembled ligands to bind RNA internal loops separated by different distances.Rational design of chemical genetic probes of RNA function and lead therapeutics targeting repeating transcripts.Developmental insights into the pathology of and therapeutic strategies for DM1: Back to the basics.Versatile on-resin synthesis of high mannose glycosylated asparagine with functional handles.Distamycin A and derivatives as synergic drugs in cisplatin-sensitive and -resistant ovarian cancer cells.Pyrrole-imidazole polyamides distinguish between double-helical DNA and RNA.Inhibitory properties of nucleic acid-binding ligands on protein synthesis.Macrocyclic DNA-mismatch-binding ligands: structural determinants of selectivity.Fluorescence spectroscopic and (19)f NMR studies of human thymidylate synthase with its cognate RNA.Insights into the development of chemical probes for RNA
P2860
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P2860
Specific binding of Hoechst 33258 to site 1 thymidylate synthase mRNA.
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Specific binding of Hoechst 33258 to site 1 thymidylate synthase mRNA.
@ast
Specific binding of Hoechst 33258 to site 1 thymidylate synthase mRNA.
@en
type
label
Specific binding of Hoechst 33258 to site 1 thymidylate synthase mRNA.
@ast
Specific binding of Hoechst 33258 to site 1 thymidylate synthase mRNA.
@en
prefLabel
Specific binding of Hoechst 33258 to site 1 thymidylate synthase mRNA.
@ast
Specific binding of Hoechst 33258 to site 1 thymidylate synthase mRNA.
@en
P2860
P356
P1476
Specific binding of Hoechst 33258 to site 1 thymidylate synthase mRNA.
@en
P2860
P304
P356
10.1093/NAR/28.10.2158
P407
P577
2000-05-01T00:00:00Z