Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner.
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Using microarrays to facilitate positional cloning: identification of tomosyn as an inhibitor of neurosecretion.Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegansDistinct initial SNARE configurations underlying the diversity of exocytosisA Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.Structural and functional analysis of tomosyn identifies domains important in exocytotic regulationStructural basis for the inhibitory role of tomosyn in exocytosisTomosyn inhibits synaptotagmin-1-mediated step of Ca2+-dependent neurotransmitter release through its N-terminal WD40 repeats.Tomosyn negatively regulates CAPS-dependent peptide release at Caenorhabditis elegans synapsesSyntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion.Tomosyn interacts with the SUMO E3 ligase PIASγ.Modulating vesicle priming reveals that vesicle immobilization is necessary but not sufficient for fusion-competence.Differential interaction of tomosyn with syntaxin and SNAP25 depends on domains in the WD40 β-propeller core and determines its inhibitory activity.Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infectionThe fusion pores of Ca2+ -triggered exocytosisPhosphorylation and degradation of tomosyn-2 de-represses insulin secretion.The N- and C-terminal domains of tomosyn play distinct roles in soluble N-ethylmaleimide-sensitive factor attachment protein receptor binding and fusion regulationPlatelet secretion and hemostasis require syntaxin-binding protein STXBP5.Low-threshold exocytosis induced by cAMP-recruited CaV3.2 (alpha1H) channels in rat chromaffin cells.Tomosyn expression pattern in the mouse hippocampus suggests both presynaptic and postsynaptic functions.SNARE complex zero layer residues are not critical for N-ethylmaleimide-sensitive factor-mediated disassembly.Differential Regulation of Synaptic Vesicle Tethering and Docking by UNC-18 and TOM-1.Factors regulating the abundance and localization of synaptobrevin in the plasma membrane.Novel copy number variants in children with autism and additional developmental anomaliesA Combined Optogenetic-Knockdown Strategy Reveals a Major Role of Tomosyn in Mossy Fiber Synaptic Plasticity.Kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes correlates with enhanced glutamate release.Tomosyn Negatively Regulates Arginine Vasopressin Secretion in Embryonic Stem Cell-Derived Neurons.PKA-catalyzed phosphorylation of tomosyn and its implication in Ca2+-dependent exocytosis of neurotransmitterNeuron-specific expression of tomosyn1 in the mouse hippocampal dentate gyrus impairs spatial learning and memory.The SNAP-25 linker as an adaptation toward fast exocytosis.Dual role of CD38 in microglial activation and activation-induced cell death.Levetiracetam prevents kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes.Opposing actions of environmental enrichment and Alzheimer's disease on the expression of hippocampal microRNAs in mouse modelsFriends and foes in synaptic transmission: the role of tomosyn in vesicle priming.Voltage-gated potassium channel as a facilitator of exocytosis.Dynamic Partitioning of Synaptic Vesicle Pools by the SNARE-Binding Protein Tomosyn.Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes.Super-resolution microscopy in studying neuroendocrine cell function.Receptor-mediated regulation of tomosyn-syntaxin 1A interactions in bovine adrenal chromaffin cells.Tomosyn associates with secretory vesicles in neurons through its N- and C-terminal domains.SUMOylation and calcium control syntaxin-1A and secretagogin sequestration by tomosyn to regulate insulin exocytosis in human ß cells.
P2860
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P2860
Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner.
description
2004 nî lūn-bûn
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2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner.
@ast
Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner.
@en
type
label
Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner.
@ast
Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner.
@en
prefLabel
Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner.
@ast
Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner.
@en
P2093
P2860
P356
P1476
Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner.
@en
P2093
Dieter Bruns
Jens Rettig
Ofer Yizhar
Rely Melamed
Uri Ashery
Yamit Hagalili
P2860
P304
P356
10.1073/PNAS.0308700100
P407
P50
P577
2004-02-01T00:00:00Z