Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice.
about
Deficient expression of DNA repair enzymes in early progression to sporadic colon cancerIncreased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome micePhysiological consequences of defects in ERCC1-XPF DNA repair endonucleaseDNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombinationA new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axisERCC1-XPF endonuclease facilitates DNA double-strand break repairThe circadian clock in cancer development and therapyBenzo[a]pyrene (BP) DNA adduct formation in DNA repair-deficient p53 haploinsufficient [Xpa(-/-)p53(+/-)] and wild-type mice fed BP and BP plus chlorophyllin for 28 daysHomeostatic imbalance between apoptosis and cell renewal in the liver of premature aging Xpd miceMuscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model.An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair.Mislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patientsCdc42 and aging of hematopoietic stem cells.Age-related dystrophic changes in corneal endothelium from DNA repair-deficient miceDeletion of p66Shc in mice increases the frequency of size-change mutations in the lacZ transgeneAge-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathologyBroad segmental progeroid changes in short-lived Ercc1(-/Δ7) miceChanges in DNA repair during aging.ERCC1/XPF limits L1 retrotranspositionMetabolism, genomics, and DNA repair in the mouse aging liver.Transcriptional profiling reveals progeroid Ercc1(-/Δ) mice as a model system for glomerular aging.DNA damage and ageing: new-age ideas for an age-old problemAnalysis of osteoarthritis in a mouse model of the progeroid human DNA repair syndrome trichothiodystrophy.Comparison of mice with accelerated aging caused by distinct mechanismsDownregulation of cholesterol biosynthesis genes in the forebrain of ERCC1-deficient miceWhole chromosome aneuploidy in the brain of Bub1bH/H and Ercc1-/Δ7 mice.DNA repair and PARP in aging.DNA damage in normally and prematurely aged mice.Effect of Ames dwarfism and caloric restriction on spontaneous DNA mutation frequency in different mouse tissuesEukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology.DNA double-strand breaks: a potential causative factor for mammalian aging?Cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity.Tissue-specific accelerated aging in nucleotide excision repair deficiencyCongenital DNA repair deficiency results in protection against renal ischemia reperfusion injury in mice.A model system for analyzing somatic mutations in Drosophila melanogasterDNA damage leads to progressive replicative decline but extends the life span of long-lived mutant animals.Haploinsufficiency in mouse models of DNA repair deficiency: modifiers of penetrance.Premature aging-related peripheral neuropathy in a mouse model of progeria.Apurinic/apyrimidinic endonuclease 1 on aging-associated deteriorations in rat kidneys.Mutation and catastrophe in the aging genome.
P2860
Q21195898-183139DB-764E-4103-95B4-F8BA6A884988Q24682525-D156AF07-EE4F-4FE5-BB56-ED217707BA90Q28238547-58C77ADD-AC36-49AD-B51C-BEBC2FCC6B71Q28263882-FB13C375-2EDE-4BE4-9E0F-5F1ACAC8D1DFQ28280037-2096127A-90E5-42FF-B22E-F469030A6BF9Q28283273-0AD9B3F2-4ED0-491F-98CD-DCDDB4703393Q28390451-E15C7197-A71A-4616-AA93-3DE151DAE276Q28391046-91A01542-BECD-4880-B468-72106FFF0A85Q28508537-D39349DD-051A-4F0D-BD3E-D88CDBD275FDQ30504731-A7D19F6B-350D-4094-B067-D5D675D6DCA8Q33396433-ACEE5970-412D-432A-8721-9A45B444EA5BQ33539726-145A292B-D43E-4352-86D7-94D4063B8935Q33753610-3545242B-1897-45A5-93D2-4E942EAA5926Q33978364-D56C7635-D2A8-4F5E-9E3C-CB42B0C61953Q34078928-EC8EC861-2847-4DE9-A500-4A7AB0620455Q34102796-DAA68108-2216-4A9E-B4B7-1F89696F14FEQ34297856-BB815770-39D2-470F-A522-52EEE03F0B70Q34697935-6B915B50-F8C5-43DF-81D1-DDEE38D181EAQ34768580-95D71525-9AA5-42AB-BD02-52948F2CC405Q34922762-1177B57D-4CCD-499E-8EE1-D7D2132C7462Q34943024-54102A2E-3C58-4030-8CD7-7C4BF7707225Q35153827-CBEE827A-73E6-4F51-B9B1-A4DF7F42850DQ35201115-81C87F48-CA8B-4724-8F00-ADE4D30C3BD5Q35732338-AA7347CF-DD48-4DEE-B7FE-71792E4465A5Q35938616-5D785915-77D0-42A4-9636-38B138D47094Q36551296-5A89328F-E2F1-49A6-B2F0-E73AD5244E3EQ36647430-2FFA243E-2C72-48F9-BAAD-991F1AB49CB2Q36847420-50FB8243-5859-4D80-8297-3AABD7888F15Q36969402-3D1F05CD-3DA3-4BD7-9B21-C049E059035CQ37048178-73594063-906C-4190-9D65-978389EA38D1Q37112251-83FAFDB9-1DCC-4B5C-B1B6-BB1ABB04C1FDQ37163184-CE029804-F7C1-4D0C-9E00-ED705637D55CQ37185712-1B5FCABE-38A8-41D9-8F0A-FD10535C5BCAQ37241018-4FA85658-42A7-4CF9-A90E-777B31C8A5CBQ37297351-7C70ECED-4006-4C5F-9812-89D3FD5FCC68Q37299465-57AC38A5-97D2-4288-BC30-BCA673B5E673Q37939634-A97DB3A3-2E3F-40A9-88B7-28B11E43BB4AQ38558947-34F043E9-B191-4CAC-B7E6-03D9BB76ED0DQ39104559-E84F6E5B-0761-4E22-8680-24DF60B15A06Q41071146-0C1025A9-282B-47A2-8563-27A4C363A0E2
P2860
Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice.
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Increased genomic instability ...... in DNA repair deficient mice.
@ast
Increased genomic instability ...... in DNA repair deficient mice.
@en
type
label
Increased genomic instability ...... in DNA repair deficient mice.
@ast
Increased genomic instability ...... in DNA repair deficient mice.
@en
prefLabel
Increased genomic instability ...... in DNA repair deficient mice.
@ast
Increased genomic instability ...... in DNA repair deficient mice.
@en
P2093
P1433
P1476
Increased genomic instability ...... in DNA repair deficient mice.
@en
P2093
Ana Maria Garcia
Ellen van Drunen
Harry van Steeg
Jan H J Hoeijmakers
Laura J Niedernhofer
Martijn E T Dollé
Rita A Busuttil
Susan Wijnhoven
P356
10.1016/J.MRFMMM.2005.11.008
P407
P577
2006-02-10T00:00:00Z