Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control - Wikidata - wikimedia - TriplyDB

Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control

Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control

http://www.wikidata.org/entity/Q36639688

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Unspliced X-box-binding protein 1 (XBP1) protects endothelial cells from oxidative stress through interaction with histone deacetylase 3 SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging Epigenetic modifications in double-strand break DNA damage signaling and repair The many roles of histone deacetylases in development and physiology: implications for disease and therapy Epigenetic Mechanisms in Bone Biology and Osteoporosis: Can They Drive Therapeutic Choices?Targeting histone deacetylases for cancer therapy: from molecular mechanisms to clinical implications Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma Histone deacetylase 3 (HDAC3) participates in the transcriptional repression of the p16 (INK4a) gene in mammary gland of the female rat offspring exposed to an early-life high-fat diet Vorinostat induces reactive oxygen species and DNA damage in acute myeloid leukemia cells Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation.Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis RNAi screen in Drosophila larvae identifies histone deacetylase 3 as a positive regulator of the hsp70 heat shock gene expression during heat shock.Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases.Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling.The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation.The therapeutic potential of class I selective histone deacetylase inhibitors in ovarian cancer Histone deacetylase inhibitors: a chemical genetics approach to understanding cellular functions.Histone deacetylase inhibitors activate NF-kappaB in human leukemia cells through an ATM/NEMO-related pathway The histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1 The clinical development of histone deacetylase inhibitors as targeted anticancer drugs.BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma Histone deacetylase 3 is required for iNKT cell development Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights.p21 Promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker.HDAC3 controls gap 2/mitosis progression in adult neural stem/progenitor cells by regulating CDK1 levels.Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells Epigenetic changes in Alzheimer's disease: decrements in DNA methylation Hdac3 is essential for the maintenance of chromatin structure and genome stability.Nuclear receptor corepressor complexes in cancer: mechanism, function and regulation Histone deacetylase inhibitors promote glioma cell death by G2 checkpoint abrogation leading to mitotic catastrophe.Histone deacetylases in skeletal development and bone mass maintenance.Inhibition of glyceroneogenesis by histone deacetylase 3 contributes to lipodystrophy in mice with adipose tissue inflammation.Spermidinyl-CoA-based HAT inhibitors block DNA repair and provide cancer-specific chemo- and radiosensitization.Interpreting clinical assays for histone deacetylase inhibitors.The optimal corepressor function of nuclear receptor corepressor (NCoR) for peroxisome proliferator-activated receptor γ requires G protein pathway suppressor 2.Suberoylanilide hydroxamic acid (SAHA) enhances olaparib activity by targeting homologous recombination DNA repair in ovarian cancer.

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Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control

http://www.wikidata.org/entity/Q36639688

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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Deletion of histone deacetylas ...... ression and DNA damage control

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Deletion of histone deacetylas ...... ression and DNA damage control

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Deletion of histone deacetylas ...... ression and DNA damage control

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Deletion of histone deacetylas ...... ression and DNA damage control

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Deletion of histone deacetylas ...... ression and DNA damage control

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Deletion of histone deacetylas ...... ression and DNA damage control

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Deletion of histone deacetylas ...... ression and DNA damage control

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Brenda J Chyla

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David Cortez

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Joseph M Amann

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Sarah K Knutson

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Scott W Hiebert

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Srividya Bhaskara

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Zu-Wen Sun

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P2860

Translating the Histone Code

Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR

Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1

Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance

HDAC6 is a microtubule-associated deacetylase

Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

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