Trisubstituted (E)-alkene dipeptide isosteres as beta-turn promoters in the gramicidin S cyclodecapeptide scaffold.
about
Peptide-Like Molecules (PLMs): A Journey from Peptide Bond Isosteres to Gramicidin S Mimetics and Mitochondrial Targeting Agents.Synthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondriaLarge-scale asymmetric synthesis of the bioprotective agent JP4-039 and analogsA Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of FerroptosisAllylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide IsosteresTherapeutic index of gramicidin S is strongly modulated by D-phenylalanine analogues at the beta-turn.Localized thermodynamic coupling between hydrogen bonding and microenvironment polarity substantially stabilizes proteins.Synthesis and biological evaluation of selective CXCR4 antagonists containing alkene dipeptide isosteres.Engineering β-sheets employing N-methylated heterochiral amino acids.Towards the synthesis of sugar amino acid containing antimicrobial noncytotoxic CAP conjugates with gold nanoparticles and a mechanistic study of cell disruption.Protein stabilization by tuning the steric restraint at the reverse turn† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc05163h.Thiazole-Based γ-Building Blocks as Reverse-Turn Mimetic to Design a Gramicidin S Analogue: Conformational and Biological Evaluation
P2860
Q28382825-5F77B273-4425-44CF-ADCD-9563CD96C85DQ28386613-28FCF0B3-F4F6-4E31-97AE-790D1408BE6FQ28388316-EC607E63-5365-40D9-9A3C-F7DE03F286D8Q28390479-7CC696B9-FDE8-4075-BFF6-D43337EB9F4AQ28396320-FB3A6FE1-A97A-4F17-807C-F054C5D8FEFFQ37138069-380A39A5-B920-4A0E-B385-73659F7868B4Q37368466-A4C602F5-126C-4162-AF31-147978F9E766Q39749640-ADADA676-18B9-4FBA-91DD-31724E302D60Q49955841-100B2652-1487-4DE6-A80F-4C7992085EE8Q52611146-8DB30227-C379-4139-A1D7-C219D5B7E709Q55063580-AC06AFA0-4971-4290-96DA-5C9A96EBD8C3Q57697366-7ABA56C4-5C32-4F11-BC67-78ED85D4328E
P2860
Trisubstituted (E)-alkene dipeptide isosteres as beta-turn promoters in the gramicidin S cyclodecapeptide scaffold.
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Trisubstituted (E)-alkene dipe ...... n S cyclodecapeptide scaffold.
@ast
Trisubstituted (E)-alkene dipe ...... n S cyclodecapeptide scaffold.
@en
Trisubstituted
@nl
type
label
Trisubstituted (E)-alkene dipe ...... n S cyclodecapeptide scaffold.
@ast
Trisubstituted (E)-alkene dipe ...... n S cyclodecapeptide scaffold.
@en
Trisubstituted
@nl
prefLabel
Trisubstituted (E)-alkene dipe ...... n S cyclodecapeptide scaffold.
@ast
Trisubstituted (E)-alkene dipe ...... n S cyclodecapeptide scaffold.
@en
Trisubstituted
@nl
P2860
P356
P1433
P1476
Trisubstituted (E)-alkene dipe ...... n S cyclodecapeptide scaffold.
@en
P2093
Bernard Weisblum
Jingbo Xiao
P2860
P304
P356
10.1021/OL0617704
P407
P50
P577
2006-10-01T00:00:00Z