SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation.
about
Suppression of La antigen exerts potential antiviral effects against hepatitis A virusScreening approaches to generating STAT inhibitors: Allowing the hits to identify the targetsA novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cellsMicroRNA-1 (miR-1) inhibits chordoma cell migration and invasion by targeting slugSTAT3 Inhibition as a Therapeutic Strategy for Chordoma.A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical librariesOleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathwayIntegrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma.Stat3-positive tumor cells contribute to vessels neoformation in primary central nervous system lymphomaThe small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells.GM-CSF-dependent pSTAT5 sensitivity is a feature with therapeutic potential in chronic myelomonocytic leukemia.Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.Interferon-γ suppresses intestinal epithelial aquaporin-1 expression via Janus kinase and STAT3 activationRole of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells.Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death.A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells.LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model.Expression of activated signal transducer and activator of transcription-3 predicts poor prognosis in cervical squamous-cell carcinoma.The tumor suppressor gene ARHI (DIRAS3) inhibits ovarian cancer cell migration through multiple mechanisms.Role of interleukin-6 in cancer progression and therapeutic resistance.PKCδ maintains phenotypes of tumor initiating cells through cytokine-mediated autocrine loop with positive feedback.MicroRNA-199a-3p is downregulated in human osteosarcoma and regulates cell proliferation and migration.XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells.An overview of cell phenotypes in HCS: limitations and advantages.Inhibitory effects of a selective Jak2 inhibitor on adrenocorticotropic hormone production and proliferation of corticotroph tumor AtT20 cells.STAT3 controls COL1A2 enhancer activation cooperatively with JunB, regulates type I collagen synthesis posttranscriptionally, and is essential for lung myofibroblast differentiation.Complexes between nuclear factor-κB p65 and signal transducer and activator of transcription 3 are key actors in inducing activation-induced cytidine deaminase expression and immunoglobulin A production in CD40L plus interleukin-10-treated human bloTwo novel SHP-1 agonists, SC-43 and SC-78, are more potent than regorafenib in suppressing the in vitro stemness of human colorectal cancer cells
P2860
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P2860
SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
SD-1029 inhibits signal transd ...... ption 3 nuclear translocation.
@ast
SD-1029 inhibits signal transd ...... ption 3 nuclear translocation.
@en
type
label
SD-1029 inhibits signal transd ...... ption 3 nuclear translocation.
@ast
SD-1029 inhibits signal transd ...... ption 3 nuclear translocation.
@en
prefLabel
SD-1029 inhibits signal transd ...... ption 3 nuclear translocation.
@ast
SD-1029 inhibits signal transd ...... ption 3 nuclear translocation.
@en
P2093
P1476
SD-1029 inhibits signal transd ...... ption 3 nuclear translocation.
@en
P2093
Edward Greenberg
James E Bradner
Jennifer Mahoney
Michael V Seiden
Rosemary Foster
Ross Levine
Zhenfeng Duan
P304
P356
10.1158/1078-0432.CCR-06-1330
P407
P577
2006-11-01T00:00:00Z