The small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells.
about
Targeting the tumor microenvironment: JAK-STAT3 signalingNF-κB and STAT3 in glioblastoma: therapeutic targets coming of ageIntegration of pathway structure information into a reweighted partial Cox regression approach for survival analysis on high-dimensional gene expression data.STAT inhibitors for cancer therapy.Anti-angiogenic activity of a small molecule STAT3 inhibitor LLL12.AZD1480 delays tumor growth in a melanoma model while enhancing the suppressive activity of myeloid-derived suppressor cells.α-type-1 polarized dendritic cell-based vaccination in recurrent high-grade glioma: a phase I clinical trial.STAT3 activation promotes oncolytic HSV1 replication in glioma cells.The Phosphoinositide 3-Kinase p110α Isoform Regulates Leukemia Inhibitory Factor Receptor Expression via c-Myc and miR-125b to Promote Cell Proliferation in Medulloblastoma.Paeoniflorin inhibits human glioma cells via STAT3 degradation by the ubiquitin-proteasome pathway.Immunosuppressive mechanisms in glioblastoma.Hydroxamic Acid and Benzoic Acid-Based STAT3 Inhibitors Suppress Human Glioma and Breast Cancer Phenotypes In Vitro and In Vivo.The role of JAK-STAT signaling within the CNS.Current and future intratumoral targeted treatment for pancreatic cancer.Caffeic Acid Inhibits Chronic UVB-Induced Cellular Proliferation Through JAK-STAT3 Signaling in Mouse Skin.STAT3 Activation in Glioblastoma: Biochemical and Therapeutic Implications.Investigation of the mutagenic and genotoxic activities of LLL-3, a STAT3 inhibitor.E804 induces growth arrest, differentiation and apoptosis of glioblastoma cells by blocking Stat3 signaling.Crispene E, a cis-clerodane diterpene inhibits STAT3 dimerization in breast cancer cells.A monocarbonyl analogue of curcumin, 1,5-bis(3-hydroxyphenyl)-1,4-pentadiene-3-one (Ca 37), exhibits potent growth suppressive activity and enhances the inhibitory effect of curcumin on human prostate cancer cells.Anticancer activity of tolfenamic acid in medulloblastoma: a preclinical study.HIV-1 Infection Primes Macrophages Through STAT Signaling to Promote Enhanced Inflammation and Viral Replication.Qianliening capsule treats benign prostatic hyperplasia via suppression of the EGF/STAT3 signaling pathway.Novel 2-Carbonylbenzo[b]thiophene 1,1-Dioxide Derivatives as Potent Inhibitors of STAT3 Signaling Pathway.Blocking interleukin-6 signaling inhibits cell viability/proliferation, glycolysis, and colony forming activity of human medulloblastoma cells.Inhibition of STAT3 enhances the radiosensitizing effect of temozolomide in glioblastoma cells in vitro and in vivo.A novel small inhibitor, LLL12, targets STAT3 in non-small cell lung cancer and
P2860
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P2860
The small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The small molecule, LLL12, inh ...... astoma and glioblastoma cells.
@ast
The small molecule, LLL12, inh ...... astoma and glioblastoma cells.
@en
type
label
The small molecule, LLL12, inh ...... astoma and glioblastoma cells.
@ast
The small molecule, LLL12, inh ...... astoma and glioblastoma cells.
@en
prefLabel
The small molecule, LLL12, inh ...... astoma and glioblastoma cells.
@ast
The small molecule, LLL12, inh ...... astoma and glioblastoma cells.
@en
P2093
P2860
P1433
P1476
The small molecule, LLL12, inh ...... astoma and glioblastoma cells.
@en
P2093
Chenglong Li
Jiayuh Lin
Pui-Kai Li
Sarah Ball
P2860
P304
P356
10.1371/JOURNAL.PONE.0018820
P407
P577
2011-04-19T00:00:00Z