Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program.
about
Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouseExpression of p16(INK4a) in peripheral blood T-cells is a biomarker of human agingResveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life spanp53 suppresses muscle differentiation at the myogenin step in response to genotoxic stressMitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator miceAn integrative network algorithm identifies age-associated differential methylation interactome hotspots targeting stem-cell differentiation pathwaysMeta-analysis of age-related gene expression profiles identifies common signatures of aging.Comparative analysis of microarray data identifies common responses to caloric restriction among mouse tissuesAge-related molecular genetic changes of murine bone marrow mesenchymal stem cells.Drosophila melanogaster p53 has developmental stage-specific and sex-specific effects on adult life span indicative of sexual antagonistic pleiotropy.Metabolic reprogramming, caloric restriction and aging.The transcription factor ATF4 promotes skeletal myofiber atrophy during fasting.Impact of Aging and Exercise on Mitochondrial Quality Control in Skeletal Muscle.Preoperative fasting protects against renal ischemia-reperfusion injury in aged and overweight mice.Physical exercise regulates p53 activity targeting SCO2 and increases mitochondrial COX biogenesis in cardiac muscle with age.p53 and ATF4 mediate distinct and additive pathways to skeletal muscle atrophy during limb immobilization.Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats.Age-related transcriptional changes in gene expression in different organs of mice support the metabolic stability theory of aging.High expression of p16INK4a and low expression of Bmi1 are associated with endothelial cellular senescence in the human cornea.The molecular balancing act of p16(INK4a) in cancer and aging.Transcriptome analysis of a long-lived natural Drosophila variant: a prominent role of stress- and reproduction-genes in lifespan extension.Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model.Controlled induction of DNA double-strand breaks in the mouse liver induces features of tissue ageing.Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy.The GATA transcription factor egl-27 delays aging by promoting stress resistance in Caenorhabditis elegans.Lifelong Physical Activity Prevents Aging-Associated Insulin Resistance in Human Skeletal Muscle Myotubes via Increased Glucose Transporter Expression.Hypothalamic microinflammation: a common basis of metabolic syndrome and aging.Age-associated increase in heterochromatic marks in murine and primate tissues.Increased Plin2 expression in human skeletal muscle is associated with sarcopenia and muscle weakness.Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy.A conserved transcriptional signature of delayed aging and reduced disease vulnerability is partially mediated by SIRT3.The metabolic footprint of aging in miceSystems biology of aging in four species.Telomere Fragment Induced Amnion Cell Senescence: A Contributor to Parturition?Visualizing the dynamics of p21(Waf1/Cip1) cyclin-dependent kinase inhibitor expression in living animals.Stress-induced skeletal muscle Gadd45a expression reprograms myonuclei and causes muscle atrophy.The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging.Nanog reverses the effects of organismal aging on mesenchymal stem cell proliferation and myogenic differentiation potentialMicroarray analysis of ageing-related signatures and their expression in tumors based on a computational biology approachHow does suppression of IGF-1 signaling by DNA damage affect aging and longevity?
P2860
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P2860
Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program.
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Gene expression profiling of a ...... iated transcriptional program.
@ast
Gene expression profiling of a ...... iated transcriptional program.
@en
Gene expression profiling of a ...... iated transcriptional program.
@nl
type
label
Gene expression profiling of a ...... iated transcriptional program.
@ast
Gene expression profiling of a ...... iated transcriptional program.
@en
Gene expression profiling of a ...... iated transcriptional program.
@nl
prefLabel
Gene expression profiling of a ...... iated transcriptional program.
@ast
Gene expression profiling of a ...... iated transcriptional program.
@en
Gene expression profiling of a ...... iated transcriptional program.
@nl
P2093
P2860
P356
P1433
P1476
Gene expression profiling of a ...... iated transcriptional program.
@en
P2093
Christina M Kendziorski
Michael G Edwards
Richard Weindruch
Rozalyn M Anderson
Tomas A Prolla
P2860
P2888
P356
10.1186/1471-2164-8-80
P407
P577
2007-03-23T00:00:00Z
P5875
P6179
1012144926