Structural and functional characterization of the mouse von Willebrand factor receptor GPIb-IX with novel monoclonal antibodies.
about
Key role of glycoprotein Ib/V/IX and von Willebrand factor in platelet activation-dependent fibrin formation at low shear flowDeadly allies: the fatal interplay between platelets and metastasizing cancer cellsRole of von Willebrand factor in tumour cell-induced platelet aggregation: differential regulation by NO and prostacyclinGlycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen.The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis.The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesisInflammation induces hemorrhage in thrombocytopenia.The kinetics of αIIbβ3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy.Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus.Morphological and functional platelet abnormalities in Berkeley sickle cell mice.Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation.CalDAG-GEFI deficiency protects mice in a novel model of Fcγ RIIA-mediated thrombosis and thrombocytopenia.FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly.The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies.CD44 antibodies and immune thrombocytopenia in the amelioration of murine inflammatory arthritis.Improved quantitative analysis of primary bone marrow megakaryocytes utilizing imaging flow cytometry.Blocking neutrophil diapedesis prevents hemorrhage during thrombocytopenia.Dimerization of glycoprotein Ibα is not sufficient to induce platelet clearance.Platelets guide the formation of early metastatic niches.In vivo evidence for platelet-induced physiological angiogenesis by a COX driven mechanism.CEACAM2 negatively regulates hemi (ITAM-bearing) GPVI and CLEC-2 pathways and thrombus growth in vitro and in vivo.Excess soluble CD40L contributes to blood brain barrier permeability in vivo: implications for HIV-associated neurocognitive disordersSerotonin stimulates platelet receptor shedding by tumor necrosis factor-alpha-converting enzyme (ADAM17)Platelets are relevant mediators of renal injury induced by primary endothelial lesionsNiacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans.ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability.Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers.Identifying and enriching platelet-producing human stem cell-derived megakaryocytes using factor V uptake.A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivoLong-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice.Maternal Par4 and platelets contribute to defective placenta formation in mouse embryos lacking thrombomodulin.Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice.Antithrombotic activity of TNF-alpha.Oxidative stress activates ADAM17/TACE and induces its target receptor shedding in platelets in a p38-dependent fashion.Ischaemic stroke: a thrombo-inflammatory disease?Glycans and the platelet life cycle.Inhibiting GPIbα Shedding Preserves Post-Transfusion Recovery and Hemostatic Function of Platelets After Prolonged Storage.A critical role of platelet adhesion in the initiation of atherosclerotic lesion formationTherapeutic expression of the platelet-specific integrin, alphaIIbbeta3, in a murine model for Glanzmann thrombasthenia.Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice.
P2860
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P2860
Structural and functional characterization of the mouse von Willebrand factor receptor GPIb-IX with novel monoclonal antibodies.
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Structural and functional char ...... h novel monoclonal antibodies.
@ast
Structural and functional char ...... h novel monoclonal antibodies.
@en
Structural and functional char ...... h novel monoclonal antibodies.
@nl
type
label
Structural and functional char ...... h novel monoclonal antibodies.
@ast
Structural and functional char ...... h novel monoclonal antibodies.
@en
Structural and functional char ...... h novel monoclonal antibodies.
@nl
prefLabel
Structural and functional char ...... h novel monoclonal antibodies.
@ast
Structural and functional char ...... h novel monoclonal antibodies.
@en
Structural and functional char ...... h novel monoclonal antibodies.
@nl
P2093
P1433
P1476
Structural and functional char ...... h novel monoclonal antibodies.
@en
P2093
Bergmeier W
Nieswandt B
Rackebrandt K
Schröder W
Zirngibl H
P304
P407
P577
2000-02-01T00:00:00Z