Hematopoietic-specific beta 1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2.
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A critical role for the transcription factor Scl in platelet production during stress thrombopoiesisMegakaryocyte biology and related disordersMegakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling.Linkage between the mechanisms of thrombocytopenia and thrombopoiesisGenomic landscape of megakaryopoiesis and platelet function defectsTranscription factors in late megakaryopoiesis and related platelet disordersRanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubulesMegakaryocyte lineage-specific class VI β-tubulin suppresses microtubule dynamics, fragments microtubules, and blocks cell division.A novel role for microtubules in apoptotic chromatin dynamics and cellular fragmentationExpression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2.Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules.The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.Integrative analysis of RUNX1 downstream pathways and target genes.The biogenesis of platelets from megakaryocyte proplatelets.Does size matter in platelet production?MKL1 and MKL2 play redundant and crucial roles in megakaryocyte maturation and platelet formation.The beta 1 tubulin R307H single nucleotide polymorphism is associated with treatment failures in immune thrombocytopenia (ITP).NF-E2 p45 is important for establishing normal function of platelets.NF-E2, FLI1 and RUNX1 collaborate at areas of dynamic chromatin to activate transcription in mature mouse megakaryocytesProplatelet formation of megakaryocytes is triggered by autocrine-synthesized estradiol.The incredible journey: From megakaryocyte development to platelet formation.Cytoskeletal mechanics of proplatelet maturation and platelet release.Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells.Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/MafDifferential roles of cAMP and cGMP in megakaryocyte maturation and platelet biogenesis.Dynamin 3 participates in the growth and development of megakaryocytes.Proplatelet generation in the mouse requires PKCε-dependent RhoA inhibition.Thrombocytogenesis by megakaryocyte; Interpretation by protoplatelet hypothesis.Thrombopoiesis is spatially regulated by the bone marrow vasculature.Microtubule polyglutamylation and acetylation drive microtubule dynamics critical for platelet formationA β1-tubulin-based megakaryocyte maturation reporter system identifies novel drugs that promote platelet productionGenetics and Expression Profile of the Tubulin Gene Superfamily in Breast Cancer Subtypes and Its Relation to Taxane Resistance
P2860
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P2860
Hematopoietic-specific beta 1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2.
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Hematopoietic-specific beta 1 ...... he transcription factor NF-E2.
@ast
Hematopoietic-specific beta 1 ...... he transcription factor NF-E2.
@en
Hematopoietic-specific beta 1 ...... he transcription factor NF-E2.
@nl
type
label
Hematopoietic-specific beta 1 ...... he transcription factor NF-E2.
@ast
Hematopoietic-specific beta 1 ...... he transcription factor NF-E2.
@en
Hematopoietic-specific beta 1 ...... he transcription factor NF-E2.
@nl
prefLabel
Hematopoietic-specific beta 1 ...... he transcription factor NF-E2.
@ast
Hematopoietic-specific beta 1 ...... he transcription factor NF-E2.
@en
Hematopoietic-specific beta 1 ...... he transcription factor NF-E2.
@nl
P2093
P1433
P1476
Hematopoietic-specific beta 1 ...... the transcription factor NF-E2
@en
P2093
Italiano JE Jr
Shivdasani RA
P304
P407
P577
2000-08-01T00:00:00Z