Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display.
about
Exploring the Secretomes of Microbes and Microbial Communities Using Filamentous Phage DisplayIntermolecular biparatopic trapping of ErbB2 prevents compensatory activation of PI3K/AKT via RAS-p110 crosstalk.Crystal Structure and Function of a DARPin Neutralizing Inhibitor of Lactococcal Phage TP901-1: COMPARISON OF DARPin AND CAMELID VHH BINDING MODEA De Novo Protein Binding Pair By Computational Design and Directed EvolutionA designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus endStructural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein librariesDevelopment of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adaptersDesign, construction, and characterization of a second-generation DARPin library with reduced hydrophobicityTracking Molecular Recognition at the Atomic Level with a New Protein Scaffold Based on the OB-FoldAdhiron: a stable and versatile peptide display scaffold for molecular recognition applicationsCombined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demiseNanomedicines based on recombinant fusion proteins for targeting therapeutic siRNA oligonucleotides.Artificial affinity proteins as ligands of immunoglobulinsEngineering of recombinant crystallization chaperonesNew binding mode to TNF-alpha revealed by ubiquitin-based artificial binding proteinFunctional display of platelet-binding VWF fragments on filamentous bacteriophageAnalysis of repeat-protein folding using nearest-neighbor statistical mechanical modelsStrategies for successful recombinant expression of disulfide bond-dependent proteins in Escherichia coli.Modern Technologies for Creating Synthetic Antibodies for Clinical application.Selection and characterization of DARPins specific for the neurotensin receptor 1Progress towards recombinant anti-infective antibodies.Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targetingPhage display and molecular imaging: expanding fields of vision in living subjects.G-quadruplexes are specifically recognized and distinguished by selected designed ankyrin repeat proteinsKnowledge-based design of a biosensor to quantify localized ERK activation in living cells.Antiviral activity of recombinant ankyrin targeted to the capsid domain of HIV-1 Gag polyprotein.Detection of biomarkers using recombinant antibodies coupled to nanostructured platformsHighly potent VEGF-A-antagonistic DARPins as anti-angiogenic agents for topical and intravitreal applications.Structural model for the interaction of a designed Ankyrin Repeat Protein with the human epidermal growth factor receptor 2.Development of a new positron emission tomography tracer for targeting tumor angiogenesis: synthesis, small animal imaging, and radiation dosimetry.DARPins: an efficient targeting domain for lentiviral vectors.Screening bicyclic peptide libraries for protein-protein interaction inhibitors: discovery of a tumor necrosis factor-α antagonistAntagonism of PDGF-BB suppresses subretinal neovascularization and enhances the effects of blocking VEGF-AThe ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility.A universal approach to prepare reagents for DNA-assisted protein analysis.Bispecific designed ankyrin repeat proteins (DARPins) targeting epidermal growth factor receptor inhibit A431 cell proliferation and receptor recyclingReceptor-Targeted Nipah Virus Glycoproteins Improve Cell-Type Selective Gene Delivery and Reveal a Preference for Membrane-Proximal Cell Attachment.Enhanced lysis by bispecific oncolytic measles viruses simultaneously using HER2/neu or EpCAM as target receptorsThe receptor attachment function of measles virus hemagglutinin can be replaced with an autonomous protein that binds Her2/neu while maintaining its fusion-helper function.Membrane domains based on ankyrin and spectrin associated with cell-cell interactions.
P2860
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P2860
Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display.
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display.
@ast
Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display.
@en
type
label
Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display.
@ast
Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display.
@en
prefLabel
Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display.
@ast
Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display.
@en
P1476
Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display.
@en
P2093
Daniel Steiner
Patrik Forrer
P304
P356
10.1016/J.JMB.2008.07.085
P407
P577
2008-08-06T00:00:00Z