Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking.
about
HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradationThe great escape: viral strategies to counter BST-2/tetherinThe formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to VpuInfectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherinRab7A is required for efficient production of infectious HIV-1Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomainThe UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domainCell-to-cell transmission of retroviruses: Innate immunity and interferon-induced restriction factorsThe restriction factors of human immunodeficiency virusHIV-1 Vpu targets cell surface markers CD4 and BST-2 through distinct mechanismsDifferential effects of human immunodeficiency virus type 1 Vpu on the stability of BST-2/tetherinBST-2/tetherin: a new component of the innate immune response to enveloped virusesAntiviral inhibition of enveloped virus release by tetherin/BST-2: action and counteractionHIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomesThe role of BST-2/Tetherin in host protection and disease manifestationRemodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and PersistenceImpacts of humanized mouse models on the investigation of HIV-1 infection: illuminating the roles of viral accessory proteins in vivoUbiquitination-mediated regulation of interferon responsesViral Membrane Channels: Role and Function in the Virus Life CycleTetherin restricts productive HIV-1 cell-to-cell transmissionDirect restriction of virus release and incorporation of the interferon-induced protein BST-2 into HIV-1 particlesStructural insight into the mechanisms of enveloped virus tethering by tetherinStructural and Biophysical Analysis of BST-2/Tetherin Ectodomains Reveals an Evolutionary Conserved Design to Inhibit Virus ReleaseCullin4A and cullin4B are interchangeable for HIV Vpr and Vpx action through the CRL4 ubiquitin ligase complexImmunoelectron microscopic evidence for Tetherin/BST2 as the physical bridge between HIV-1 virions and the plasma membraneQuantitative multicolor super-resolution microscopy reveals tetherin HIV-1 interaction.Expression of HIV-1 Vpu leads to loss of the viral restriction factor CD317/Tetherin from lipid rafts and its enhanced lysosomal degradationMechanism of HIV-1 virion entrapment by tetherinThe HIV mutation browser: a resource for human immunodeficiency virus mutagenesis and polymorphism dataImmune Activation Influences SAMHD1 Expression and Vpx-mediated SAMHD1 Degradation during Chronic HIV-1 InfectionHSV-2 glycoprotein gD targets the CC domain of tetherin and promotes tetherin degradation via lysosomal pathwayCounteraction of the multifunctional restriction factor tetherinThe HIV-1 Vpu viroporin inhibitor BIT225 does not affect Vpu-mediated tetherin antagonismActivities of transmitted/founder and chronic clade B HIV-1 Vpu and a C-terminal polymorphism specifically affecting virion releaseDifferential sensitivities of tetherin isoforms to counteraction by primate lentiviruses.Tetherin Sensitivity of Influenza A Viruses Is Strain Specific: Role of Hemagglutinin and Neuraminidase.Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.Modulation of HIV-1-host interaction: role of the Vpu accessory proteinLack of adaptation to human tetherin in HIV-1 group O and P.
P2860
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P2860
Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Vpu antagonizes BST-2-mediated ...... nd endo-lysosomal trafficking.
@ast
Vpu antagonizes BST-2-mediated ...... nd endo-lysosomal trafficking.
@en
type
label
Vpu antagonizes BST-2-mediated ...... nd endo-lysosomal trafficking.
@ast
Vpu antagonizes BST-2-mediated ...... nd endo-lysosomal trafficking.
@en
prefLabel
Vpu antagonizes BST-2-mediated ...... nd endo-lysosomal trafficking.
@ast
Vpu antagonizes BST-2-mediated ...... nd endo-lysosomal trafficking.
@en
P2093
P2860
P1433
P1476
Vpu antagonizes BST-2-mediated ...... nd endo-lysosomal trafficking.
@en
P2093
Autumn Ruiz
Chris Katsura
Edward B Stephens
John C Guatelli
Katie Fitzpatrick
Mark A Skasko
Richard Benarous
Richard S Mitchell
P2860
P304
P356
10.1371/JOURNAL.PPAT.1000450
P577
2009-05-29T00:00:00Z