Phage-encoded combinatorial chemical libraries based on bicyclic peptides.
about
Recent Advances Toward the Discovery of Drug-Like Peptides De novoCyclic and Macrocyclic Peptides as Chemical Tools To Recognise Protein Surfaces and Probe Protein-Protein InteractionsTargeting the Eph System with Peptides and Peptide ConjugatesChemical strategies for the covalent modification of filamentous phageGetting in shape: controlling peptide bioactivity and bioavailability using conformational constraintsImproving binding affinity and stability of peptide ligands by substituting glycines with D-amino acidsPeptide ligands stabilized by small moleculesChemical generation and modification of peptides containing multiple dehydroalaninesConstraining cyclic peptides to mimic protein structure motifs.Phage Selection of Bicyclic Peptide Ligands of the Notch1 Receptor.Towards vast libraries of scaffold-diverse, conformationally constrained oligomers.Practical tips for construction of custom Peptide libraries and affinity selection by using commercially available phage display cloning systemsScaffold optimization in discontinuous epitope containing protein mimics of gp120 using smart libraries.In vitro methods for peptide display and their applications.Bacterial display and screening of posttranslationally thioether-stabilized peptides.20 years of DNA-encoded chemical libraries.Discovery of macrocyclic peptides armed with a mechanism-based warhead: isoform-selective inhibition of human deacetylase SIRT2.In vitro selection of highly modified cyclic peptides that act as tight binding inhibitors.Structurally diverse cyclisation linkers impose different backbone conformations in bicyclic peptides.Polycyclic peptide therapeutics.A combinatorial approach toward smart libraries of discontinuous epitopes of HIV gp120 on a TAC synthetic scaffold.Biopharmaceuticals and monoclonal antibodies in oncology trials--a cross-sectional analysisGenetically encoded libraries of nonstandard peptides.Phage selection of cyclic peptide antagonists with increased stability toward intestinal proteases.mRNA display selection and solid-phase synthesis of Fc-binding cyclic peptide affinity ligands.Peptide and small molecule inhibitors of HECT-type ubiquitin ligasesTechnologies for the synthesis of mRNA-encoding libraries and discovery of bioactive natural product-inspired non-traditional macrocyclic peptides.Chemical modulation of M13 bacteriophage and its functional opportunities for nanomedicine.A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibilityScreening bicyclic peptide libraries for protein-protein interaction inhibitors: discovery of a tumor necrosis factor-α antagonistDevelopment of Next-Generation Peptide Binders Using In vitro Display Technologies and Their Potential Applications.In vitro affinity screening of protein and peptide binders by megavalent bead surface display.Gp10 based-thioetherification (10BASE(d)-T) on a displaying library peptide of bacteriophage T7.Synthetic covalently linked dimeric form of H2 relaxin retains native RXFP1 activity and has improved in vitro serum stability.Tracking chemical reactions on the surface of filamentous phage using mass spectrometry.Convergent diversity-oriented side-chain macrocyclization scan for unprotected polypeptides.Pharmacophore generation from a drug-like core molecule surrounded by a library peptide via the 10BASEd-T on bacteriophage T7.Scaffolded multiple cyclic peptide libraries for protein mimics by native chemical ligation.Peptides come round: using SICLOPPS libraries for early stage drug discovery.Enzyme-catalyzed macrocyclization of long unprotected peptides.
P2860
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P2860
Phage-encoded combinatorial chemical libraries based on bicyclic peptides.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Phage-encoded combinatorial chemical libraries based on bicyclic peptides.
@ast
Phage-encoded combinatorial chemical libraries based on bicyclic peptides.
@en
type
label
Phage-encoded combinatorial chemical libraries based on bicyclic peptides.
@ast
Phage-encoded combinatorial chemical libraries based on bicyclic peptides.
@en
prefLabel
Phage-encoded combinatorial chemical libraries based on bicyclic peptides.
@ast
Phage-encoded combinatorial chemical libraries based on bicyclic peptides.
@en
P2093
P356
P1476
Phage-encoded combinatorial chemical libraries based on bicyclic peptides.
@en
P2093
Christian Heinis
Greg Winter
Stephan Freund
Trevor Rutherford
P2888
P304
P356
10.1038/NCHEMBIO.184
P50
P577
2009-07-01T00:00:00Z