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Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.

Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.

http://www.wikidata.org/entity/Q33526747

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Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α)Preclinical Data on Efficacy of 10 Drug-Radiation Combinations: Evaluations, Concerns, and Recommendations Imaging tumor hypoxia to advance radiation oncology The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy Adaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat Spalax CYP450 Enzymes Effect Oxygen-Dependent Reduction of Azide-Based Fluorogenic Dyes Glioblastoma cells inhibit astrocytic p53-expression favoring cancer malignancy Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication Quantitative assessment of hypoxia subtypes in microcirculatory supply units of malignant tumors using (immuno-)fluorescence techniques.A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion.Acute versus chronic hypoxia in tumors: Controversial data concerning time frames and biological consequences.Vascular responses to radiotherapy and androgen-deprivation therapy in experimental prostate cancer.Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment.Hypoxia as a biomarker for radioresistant cancer stem cells.Identification of a stem-like cell population by exposing metastatic breast cancer cell lines to repetitive cycles of hypoxia and reoxygenation Biphasic regulation of autophagy by miR-96 in prostate cancer cells under hypoxia.Tumor hypoxia and genetic alterations in sporadic cancers.A microfluidic device to study cancer metastasis under chronic and intermittent hypoxia.Reciprocal influence of the p53 and the hypoxic pathways Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance Expression profile and in silico characterization of novel RTF2h gene under oxidative stress in Indian catfish, Clarias magur (Hamilton 1822).Linking hypoxia, DNA damage and proliferation in multicellular tumor spheroids Mechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1.LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis.Pilot study of PET imaging of 124I-iodoazomycin galactopyranoside (IAZGP), a putative hypoxia imaging agent, in patients with colorectal cancer and head and neck cancer.Biogenesis of intronic miRNAs located in clusters by independent transcription and alternative splicing Genome maintenance and bioenergetics of the long-lived hypoxia-tolerant and cancer-resistant blind mole rat, Spalax: a cross-species analysis of brain transcriptome.Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancer.Targeting hypoxic cells through the DNA damage response.Glioblastoma, cancer stem cells and hypoxia.Tumor hypoxia as a driving force in genetic instability.Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment Molecular Pathways: Targeting ATR in Cancer Therapy Isolation of Proteins on Nascent DNA in Hypoxia and Reoxygenation Conditions.Measuring DNA Replication in Hypoxic Conditions.ATM activation in hypoxia - causes and consequences.Replication stress and chromatin context link ATM activation to a role in DNA replication.CH-01 is a hypoxia-activated prodrug that sensitizes cells to hypoxia/reoxygenation through inhibition of Chk1 and Aurora A.Differential gene expression in human fibroblasts after alpha-particle emitter (211)At compared with (60)Co irradiation.

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P2860

Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.

http://www.wikidata.org/entity/Q33526747

description

2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.

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Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.

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Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.

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type

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Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.

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Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.

@en

Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.

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prefLabel

Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.

@ast

Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.

@en

Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.

@nl

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0008-5472.CAN-09-2715

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Cancer Research

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Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.

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P2093

Ester M Hammond

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Ji-Liang Li

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Lisa K Folkes

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Manuela Milani

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Mike R Stratford

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Zuzana Bencokova

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P2860

A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication

Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

Cell growth-regulated expression of mammalian MCM5 and MCM6 genes mediated by the transcription factor E2F

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

Lysyl oxidase is essential for hypoxia-induced metastasis

Exploiting tumour hypoxia in cancer treatment

Genome instability: a mechanistic view of its causes and consequences

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

Ribonucleotide reductases

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Adrian L Harris

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2010-01-26T00:00:00Z

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20103649

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