Antagonism of tetherin restriction of HIV-1 release by Vpu involves binding and sequestration of the restriction factor in a perinuclear compartment
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Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1The restriction factors of human immunodeficiency virusHIV-1 Vpu targets cell surface markers CD4 and BST-2 through distinct mechanismsDifferential effects of human immunodeficiency virus type 1 Vpu on the stability of BST-2/tetherinBST-2/tetherin: a new component of the innate immune response to enveloped virusesAntiviral inhibition of enveloped virus release by tetherin/BST-2: action and counteractionThe role of BST-2/Tetherin in host protection and disease manifestationRemodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and PersistenceStructural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformationsStructural insight into the mechanisms of enveloped virus tethering by tetherinStructural and Biophysical Analysis of BST-2/Tetherin Ectodomains Reveals an Evolutionary Conserved Design to Inhibit Virus ReleaseExpression of HIV-1 Vpu leads to loss of the viral restriction factor CD317/Tetherin from lipid rafts and its enhanced lysosomal degradationMechanism of HIV-1 virion entrapment by tetherinInterferon-induced tetherin restricts vesicular stomatitis virus release in neuronsHSV-2 glycoprotein gD targets the CC domain of tetherin and promotes tetherin degradation via lysosomal pathwayIntrinsic cellular defenses against human immunodeficiency virusesCounteraction of tetherin antiviral activity by two closely related SIVs differing by the presence of a Vpu geneVpu and BST2: Still Not There Yet?Activities of transmitted/founder and chronic clade B HIV-1 Vpu and a C-terminal polymorphism specifically affecting virion releaseDifferential sensitivities of tetherin isoforms to counteraction by primate lentiviruses.Tetherin/BST-2: Restriction Factor or Immunomodulator?Differential Control of BST2 Restriction and Plasmacytoid Dendritic Cell Antiviral Response by Antagonists Encoded by HIV-1 Group M and O Strains.Modulation of HIV-1-host interaction: role of the Vpu accessory proteinLack of adaptation to human tetherin in HIV-1 group O and P.HIV-1 Group P is unable to antagonize human tetherin by Vpu, Env or Nef.Eastern chimpanzees, but not bonobos, represent a simian immunodeficiency virus reservoir.Human tetherin exerts strong selection pressure on the HIV-1 group N Vpu protein.The transmembrane domain of HIV-1 Vpu is sufficient to confer anti-tetherin activity to SIVcpz and SIVgor Vpu proteins: cytoplasmic determinants of Vpu functionA Genetic Screen Identifies a Critical Role for the WDR81-WDR91 Complex in the Trafficking and Degradation of Tetherin.The ESCRT-0 component HRS is required for HIV-1 Vpu-mediated BST-2/tetherin down-regulation.BST-2/tetherin-mediated restriction of chikungunya (CHIKV) VLP budding is counteracted by CHIKV non-structural protein 1 (nsP1)HIV-1 Vpu antagonism of tetherin inhibits antibody-dependent cellular cytotoxic responses by natural killer cells.Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu.RIG-I-mediated antiviral signaling is inhibited in HIV-1 infection by a protease-mediated sequestration of RIG-I.A single nucleotide polymorphism in tetherin promotes retrovirus restriction in vivo.A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction.The HIV-1 Vpu protein induces apoptosis in Drosophila via activation of JNK signalingCell-cell spread of human immunodeficiency virus type 1 overcomes tetherin/BST-2-mediated restriction in T cells.How Ebola virus counters the interferon system.Novel factors interfering with human immunodeficiency virus-type 1 replication in vivo and in vitro.
P2860
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P2860
Antagonism of tetherin restriction of HIV-1 release by Vpu involves binding and sequestration of the restriction factor in a perinuclear compartment
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Antagonism of tetherin restric ...... r in a perinuclear compartment
@ast
Antagonism of tetherin restric ...... r in a perinuclear compartment
@en
Antagonism of tetherin restric ...... in a perinuclear compartment.
@nl
type
label
Antagonism of tetherin restric ...... r in a perinuclear compartment
@ast
Antagonism of tetherin restric ...... r in a perinuclear compartment
@en
Antagonism of tetherin restric ...... in a perinuclear compartment.
@nl
prefLabel
Antagonism of tetherin restric ...... r in a perinuclear compartment
@ast
Antagonism of tetherin restric ...... r in a perinuclear compartment
@en
Antagonism of tetherin restric ...... in a perinuclear compartment.
@nl
P2093
P2860
P1433
P1476
Antagonism of tetherin restric ...... r in a perinuclear compartment
@en
P2093
Antoine Chiasson
Bibhuti Bhusan Roy
Eric A Cohen
Johanne Mercier
Julie Binette
Mathieu Dubé
Pierre Guiot-Guillain
P2860
P304
P356
10.1371/JOURNAL.PPAT.1000856
P577
2010-04-08T00:00:00Z