Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells
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Adiponectin signaling and function in insulin target tissues5'-Monophosphate-activated protein kinase (AMPK) improves autophagic activity in diabetes and diabetic complicationsMembrane Curvature Protein Exhibits Interdomain Flexibility and Binds a Small GTPaseAPPL proteins FRET at the BAR: direct observation of APPL1 and APPL2 BAR domain-mediated interactions on cell membranes using FRET microscopyA possible mechanism behind autoimmune disorders discovered by genome-wide linkage and association analysis in celiac diseaseDelivery of adiponectin gene to skeletal muscle using ultrasound targeted microbubbles improves insulin sensitivity and whole body glucose homeostasisFull-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino Acid transport in human primary trophoblast cellsGlobular adiponectin, acting via AdipoR1/APPL1, protects H9c2 cells from hypoxia/reoxygenation-induced apoptosisAdiponectin signaling in the liverGenetic variations in APPL2 are associated with overweight and obesity in a Chinese population with normal glucose tolerance.Absence of Appl2 sensitizes endotoxin shock through activation of PI3K/Akt pathway.APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway.Association of genetic variation in adaptor protein APPL1/APPL2 loci with non-alcoholic fatty liver diseaseThe adaptor protein APPL1 increases glycogen accumulation in rat skeletal muscle through activation of the PI3-kinase signalling pathwayRab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophagesAPPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor.APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathwayAPPL1 counteracts obesity-induced vascular insulin resistance and endothelial dysfunction by modulating the endothelial production of nitric oxide and endothelin-1 in mice.G-protein-coupled receptor kinase 2-mediated desensitization of adiponectin receptor 1 in failing heart.Adiponectin-AdipoR1/2-APPL1 signaling axis suppresses human foam cell formation: differential ability of AdipoR1 and AdipoR2 to regulate inflammatory cytokine responses.Adiponectin and cardiovascular health: an updateAdiponectin action: a combination of endocrine and autocrine/paracrine effects.Deficiency of APPL1 in mice impairs glucose-stimulated insulin secretion through inhibition of pancreatic beta cell mitochondrial function.APPL1-Mediating Leptin Signaling Contributes to Proliferation and Migration of Cancer Cells.Appl1 and Appl2 are Expendable for Mouse Development But Are Essential for HGF-Induced Akt Activation and Migration in Mouse Embryonic Fibroblasts.Altered endosome biogenesis in prostate cancer has biomarker potential.Antidiabetic treatment restores adiponectin serum levels and APPL1 expression, but does not improve adiponectin-induced vasodilation and endothelial dysfunction in Zucker diabetic fatty rats.Review: Adiponectin--the missing link between maternal adiposity, placental transport and fetal growth?Lack of adiponectin leads to increased lymphocyte activation and increased disease severity in a mouse model of multiple sclerosis.Adipokines and the female reproductive tract.Adiponectin inhibits insulin function in primary trophoblasts by PPARα-mediated ceramide synthesis.Molecular mechanisms of signal transduction via adiponectin and adiponectin receptors.The role of adiponectin signaling in metabolic syndrome and cancer.Skeletal muscle glucose metabolism and inflammation in the development of the metabolic syndrome.Role of Rab GTPases and their interacting proteins in mediating metabolic signalling and regulation.Palmitate induces ER stress and autophagy in H9c2 cells: implications for apoptosis and adiponectin resistance.Role of microRNAs on the Regulation of Mitochondrial Biogenesis and Insulin Signaling in Skeletal Muscle.APPL1 is a multifunctional endosomal signaling adaptor protein.Distinct Roles for APPL1 and APPL2 in Regulating Toll-like Receptor 4 Signaling in Macrophages.Skeletal muscle inflammation is not responsible for the rapid impairment in adiponectin response with high-fat feeding in rats.
P2860
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P248
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P2860
Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells
@ast
Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells
@en
Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells.
@nl
type
label
Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells
@ast
Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells
@en
Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells.
@nl
prefLabel
Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells
@ast
Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells
@en
Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells.
@nl
P2093
P2860
P921
P356
P1476
Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells
@en
P2093
Changhua Wang
Fresnida J Ramos
Hak Joo Lee
Hongzhi Chen
Lily Q Dong
Meilian Liu
Ruihua Xiang
Xiaoban Xin
Xuming Mao
P2860
P304
31608-31615
P356
10.1074/JBC.M109.010355
P407
P577
2009-08-06T00:00:00Z