High-level beta-globin expression after retroviral transfer of locus activation region-containing human beta-globin gene derivatives into murine erythroleukemia cells.
about
Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene.Gene therapy for hemoglobinopathies: the state of the field and the future.Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells.Retroviral transfer of a human beta-globin/delta-globin hybrid gene linked to beta locus control region hypersensitive site 2 aimed at the gene therapy of sickle cell disease.An Erythroid-Specific Chromatin Opening Element Increases β-Globin Gene Expression from Integrated Retroviral Gene Transfer Vectors.Globin gene transfer for the treatment of severe hemoglobinopathies: a paradigm for stem cell-based gene therapy.Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells.Adeno-associated virus type 2-mediated transduction of murine hematopoietic cells with long-term repopulating ability and sustained expression of a human globin gene in vivo.Structure and function of the murine beta-globin locus control region 5' HS-3.Genetic treatment of a molecular disorder: gene therapy approaches to sickle cell disease.Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the β(A(T87Q))-Globin Gene.A 36-base-pair core sequence of locus control region enhances retrovirally transferred human beta-globin gene expression.Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vectorMutagenesis of retroviral vectors transducing human beta-globin gene and beta-globin locus control region derivatives results in stable transmission of an active transcriptional structureGene therapy for β-thalassaemia: the continuing challenge.Gene therapy in thalassemia and hemoglobinopathies.Peripheral blood stem cells: phenotypic diversity and potential clinical applications.Recent advances in gene therapy for thalassemia.Development of gene therapy for thalassemia.Slow and Steady Wins The Race? Progress in the Development of Vectors for Gene Therapy of β-Thalassemia and Sickle Cell Disease.Comparative analysis of FV vectors with human α- or β-globin gene regulatory elements for the correction of β-thalassemia.Locus control region of the human CD2 gene in a lentivirus vector confers position-independent transgene expression.The Ongoing Challenge of Hematopoietic Stem Cell-Based Gene Therapy for β-Thalassemia.Characterization of a DNA binding activity in DNAse I hypersensitive site 4 of the human globin locus control region.Retroviral vectors for the beta-globin gene that demonstrate improved titer and expression.Recombinant AAV2-mediated β-globin expression in human fetal hematopoietic cells from the aborted fetuses with β-thalassemia major.An in vitro system for efficiently evaluating gene therapy approaches to hemoglobinopathies.
P2860
Q34073641-91848B18-A2ED-4D28-B13C-ED4C486030ECQ34204480-E1C85A06-E691-45AE-AD3A-FBCC5E5EBB94Q34393866-3FB8946E-2EAD-4BB0-BF87-E2D439CD538FQ34528437-3FFAFC3D-4BE8-4311-91F5-681D5D469F4CQ34586740-F61F254C-B0DF-45EA-B231-3B6C2826FCB0Q34587615-807E9054-9546-4EDB-9E58-5026477A70A7Q34626844-A15A34F2-6A8E-492F-BF52-0BF68884E2FDQ35837539-6CD33CA9-4AAF-4DAF-A483-6CC6FC7E5196Q35881204-AEEFB52B-7A17-4EE7-9A9C-8F6550F00F29Q35933696-4B6D718F-42A5-4F90-92D4-504B34858CF3Q36596865-8E685DC6-7E45-45A7-885F-760E2F1733AFQ36654528-942F5E75-E1C4-4C18-A4A9-877B88737145Q36938516-3F7339F8-402C-47C1-B40B-81F374869290Q37142195-F8101181-DFA3-4957-B4FF-FA812DE4E83DQ37634171-4E4073D4-B1B1-4207-A782-513FCE9C96EBQ37795125-DE1B053C-BCDF-4CF3-82F5-97A2029AD822Q37854468-F3B6F77F-0CCC-4946-95BB-590014A118A5Q37997392-A04F6147-B6BD-4E7A-97C1-E718262C4C66Q38038167-892D7DF6-00AF-454B-BE7A-E6535D518EAEQ38057725-A26D8701-AC63-4CBB-B6EC-99FFA879AC35Q38900001-3F89079E-D04E-4748-B660-41D568BB5ACCQ39511486-19B3D82A-114C-49F8-9006-293F04DE4C6FQ39602685-4F1E6EF6-5CD1-4F76-87DE-665BD462B1CAQ39749114-3DB954E8-5C35-4B72-B9D9-EF5AF9F92746Q40507589-2DCD1DFD-2E3F-434A-95D6-1FFB1D9FF461Q41751058-2DD9AED7-A625-4886-9B3B-AAF49A2B6E3FQ43502862-CD911B85-A44A-4FAE-B908-7498124CAF98Q45865591-56FCC1EF-C0F2-47E8-8DFF-A168AD5AD1F7
P2860
High-level beta-globin expression after retroviral transfer of locus activation region-containing human beta-globin gene derivatives into murine erythroleukemia cells.
description
1990 nî lūn-bûn
@nan
1990 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
High-level beta-globin express ...... murine erythroleukemia cells.
@ast
High-level beta-globin express ...... murine erythroleukemia cells.
@en
High-level beta-globin express ...... murine erythroleukemia cells.
@nl
type
label
High-level beta-globin express ...... murine erythroleukemia cells.
@ast
High-level beta-globin express ...... murine erythroleukemia cells.
@en
High-level beta-globin express ...... murine erythroleukemia cells.
@nl
prefLabel
High-level beta-globin express ...... murine erythroleukemia cells.
@ast
High-level beta-globin express ...... murine erythroleukemia cells.
@en
High-level beta-globin express ...... murine erythroleukemia cells.
@nl
P2093
P2860
P356
P1476
High-level beta-globin express ...... murine erythroleukemia cells.
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.9.3386
P407
P577
1990-05-01T00:00:00Z