High-level erythroid expression of human alpha-globin genes in transgenic mice. - Wikidata - wikimedia - TriplyDB

High-level erythroid expression of human alpha-globin genes in transgenic mice.

High-level erythroid expression of human alpha-globin genes in transgenic mice.

http://www.wikidata.org/entity/Q33827437

about

The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome High-level beta-globin expression after retroviral transfer of locus activation region-containing human beta-globin gene derivatives into murine erythroleukemia cells.Human gamma-globin gene promoter element regulates human beta-globin gene developmental specificity Conservation of the primary structure, organization, and function of the human and mouse beta-globin locus-activating regions.Beta-globin locus activation regions: conservation of organization, structure, and function The beta-globin dominant control region: hypersensitive site 2 Detailed analysis of the site 3 region of the human beta-globin dominant control region Analysis of the human alpha globin upstream regulatory element (HS-40) in transgenic mice Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene.Molecular analysis of the human beta-globin locus activation region.The human beta-globin locus activation region alters the developmental fate of a human fetal globin gene in transgenic mice.Gamma delta beta-thalassemia due to a de novo mutation deleting the 5' beta-globin gene activation-region hypersensitive sites.Silencing of gene expression: implications for design of retrovirus vectors.A 46 base pair enhancer sequence within the locus activating region is required for induced expression of the gamma-globin gene during erythroid differentiation.DNaseI hypersensitive sites 1, 2 and 3 of the human beta-globin dominant control region direct position-independent expression Developmental regulation of the human zeta globin gene in transgenic mice.Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase.Rhabdomyosarcoma arising in transgenic mice harboring the beta-globin locus control region fused with simian virus 40 large T antigen gene.Production of unmodified human adult hemoglobin in Escherichia coli A globin enhancer acts by increasing the proportion of erythrocytes expressing a linked transgene.Human alpha-globin genes demonstrate autonomous developmental regulation in transgenic mice.The mitochondrial uncoupling protein gene in brown fat: correlation between DNase I hypersensitivity and expression in transgenic mice.Restriction of neuroblastoma to the prostate gland in transgenic mice.Beta-globin enhancers target expression of a heterologous gene to erythroid tissues of transgenic mice.Regulated expression of globin chains and the erythroid transcription factor GATA-1 during erythropoiesis in the developing mouse.Regulated expression of human alpha- and beta-globin genes in transient heterokaryons Humanized Mouse Model of Cooley's Anemia.Activation of the beta-globin locus control region precedes commitment to the erythroid lineage.High expression of human beta S- and alpha-globins in transgenic mice: hemoglobin composition and hematological consequences Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice The alpha-thalassemias.CACCC and GATA-1 sequences make the constitutively expressed alpha-globin gene erythroid-responsive in mouse erythroleukemia cells.CpG islands from the alpha-globin gene cluster increase gene expression in an integration-dependent manner.The proximal element of the beta globin locus control region is not functionally required in vivo.The LCR-like alpha-globin positive regulatory element functions as an enhancer in transiently transfected cells during erythroid differentiation Adult chicken alpha-globin gene expression in transfected QT6 quail cells: evidence for a negative regulatory element in the alpha D gene region Developmentally regulated and erythroid-specific expression of the human embryonic beta-globin gene in transgenic mice The mouse beta-globin locus control region: hypersensitive sites 3 and 4.Characterization of the major regulatory element upstream of the human alpha-globin gene cluster.Position-independent expression of the ovine beta-lactoglobulin gene in transgenic mice.

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P2860

High-level erythroid expression of human alpha-globin genes in transgenic mice.

http://www.wikidata.org/entity/Q33827437

description

1989 nî lūn-bûn

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1989 թուականի Յունուարին հրատարակուած գիտական յօդուած

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1989 թվականի հունվարին հրատարակված գիտական հոդված

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1989年の論文

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1989年論文

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1989年論文

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1989年論文

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1989年論文

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1989年論文

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1989年论文

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name

High-level erythroid expression of human alpha-globin genes in transgenic mice.

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High-level erythroid expression of human alpha-globin genes in transgenic mice.

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type

label

High-level erythroid expression of human alpha-globin genes in transgenic mice.

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High-level erythroid expression of human alpha-globin genes in transgenic mice.

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prefLabel

High-level erythroid expression of human alpha-globin genes in transgenic mice.

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High-level erythroid expression of human alpha-globin genes in transgenic mice.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

High-level erythroid expression of human alpha-globin genes in transgenic mice.

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P2093

R D Palmiter

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R L Brinster

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R R Behringer

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T M Ryan

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T M Townes

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P2860

The "beta-like-globin" gene domain in human erythroid cells

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

Erythroid-specific expression of human beta-globin genes in transgenic mice.

Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences.

Three mouse models of human thalassemia.

A developmentally stable chromatin structure in the human beta-globin gene cluster

Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

Expression of human beta-globin genes in transgenic mice: effects of a flanking metallothionein-human growth hormone fusion gene.

cis and trans activation of globin gene transcription in transient assays.

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37-41

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10.1073/PNAS.86.1.37

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1

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86

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2911581

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286398

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