about
Intrabody and Parkinson's diseaseGeneration of human antibody fragments recognizing distinct epitopes of the nucleocapsid (N) SARS-CoV protein using a phage display approachFunctional inactivation of the conserved Sem1p in yeast by intrabodies.In-cell intrabody selection from a diverse human library identifies C12orf4 protein as a new player in rodent mast cell degranulationSingle domain intrabodies against WASP inhibit TCR-induced immune responses in transgenic mice T cells.Selection of phage-displayed fab antibodies on the active conformation of ras yields a high affinity conformation-specific antibody preventing the binding of c-Raf kinase to Ras.Diverting a protein from its cellular location by intracellular antibodies. The case of p21Ras.Inhibition of human cytomegalovirus replication via peptide aptamers directed against the nonconventional nuclear localization signal of the essential viral replication factor pUL84.Physico-chemical determinants of soluble intrabody expression in mammalian cell cytoplasm.Aggresome formation by anti-Ras intracellular scFv fragments. The fate of the antigen-antibody complex.Consensus design of repeat proteins.Engineering antibody fragments to fold in the absence of disulfide bonds.Conformational targeting of fibrillar polyglutamine proteins in live cells escalates aggregation and cytotoxicity.Engineering antibody fitness and function using membrane-anchored display of correctly folded proteins.Optimizing recombinant antibodies for intracellular function using hitchhiker-mediated survival selectionGeneration and characterization of a novel recombinant antibody against LMP1-TES1 of Epstein-Barr virus isolated by phage display.A study of the mechanism of the chaperone-like function of an scFv of human creatine kinase by computer simulationIntrabodies based on intracellular capture frameworks that bind the RAS protein with high affinity and impair oncogenic transformationPeptide-mediated broad-spectrum plant resistance to tospoviruses.The Pyk2 FERM domain as a target to inhibit glioma migration.Inhibition of protease-inhibitor-resistant hepatitis C virus replicons and infectious virus by intracellular intrabodies.Potential applications of intracellular antibodies (intrabodies) in stem cell therapeutics.Intrabody strategies for the treatment of human papillomavirus-associated disease.State of the art in tumor antigen and biomarker discovery.Novel antibody derivatives for proteome and high-content analysis.Modification of the ionizing radiation response in living cells by an scFv against the DNA-dependent protein kinase.Adenovirus targeting to HLA-A1/MAGE-A1-positive tumor cells by fusing a single-chain T-cell receptor with minor capsid protein IX.Efficient incorporation of a functional hyper-stable single-chain antibody fragment protein-IX fusion in the adenovirus capsid.Tropism modification of adenovirus vectors by peptide ligand insertion into various positions of the adenovirus serotype 41 short-fiber knob domain.Role of native-state topology in the stabilization of intracellular antibodies.Trapping prion protein in the endoplasmic reticulum impairs PrPC maturation and prevents PrPSc accumulation.Disruption of P-glycoprotein anticancer drug efflux activity by a small recombinant single-chain Fv antibody fragment targeted to an extracellular epitope.Inhibition of the EGF-induced activation of phospholipase C-gamma1 by a single chain antibody fragment.Evidence for proteasome dysfunction in cytotoxicity mediated by anti-Ras intracellular antibodies.Intrabody construction and expression III: engineering hyperstable V(H) domains.In vivo expression and binding activity of scFv-RWAV, which recognizes the coat protein of tomato leaf curl New Delhi virus (family Geminiviridae).Genetic retargeting of adenovirus vectors: functionality of targeting ligands and their influence on virus viability.Targeting multidrug resistant tumor cells with a recombinant single-chain FV fragment directed to P-glycoprotein.
P2860
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P2860
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The selection of intracellular antibodies.
@ast
The selection of intracellular antibodies.
@en
The selection of intracellular antibodies.
@nl
type
label
The selection of intracellular antibodies.
@ast
The selection of intracellular antibodies.
@en
The selection of intracellular antibodies.
@nl
prefLabel
The selection of intracellular antibodies.
@ast
The selection of intracellular antibodies.
@en
The selection of intracellular antibodies.
@nl
P1476
The selection of intracellular antibodies
@en
P2093
P304
P356
10.1016/S0167-7799(98)01268-2
P577
1999-03-01T00:00:00Z