Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders.
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Neurosteroids and GABA(A) Receptor Interactions: A Focus on StressStress, seizures, and hypothalamic-pituitary-adrenal axis targets for the treatment of epilepsyNeurosteroids: endogenous regulators of the GABA(A) receptorCocaine-, caffeine-, and stress-evoked cocaine reinstatement in high vs. low impulsive rats: treatment with allopregnanolone.The impact of gonadectomy and adrenalectomy on acute withdrawal severity in male and female C57BL/6J and DBA/2J mice following a single high dose of ethanol.Replacement with GABAergic steroid precursors restores the acute ethanol withdrawal profile in adrenalectomy/gonadectomy mice.17beta-Nitro-5alpha-androstan-3alpha-ol and its 3beta-methyl derivative: neurosteroid analogs with potent anticonvulsant and anxiolytic activities.Neuroactive steroids: their mechanism of action and their function in the stress response.Structurally diverse amphiphiles exhibit biphasic modulation of GABAA receptors: similarities and differences with neurosteroid actions.Kinetic and structural determinants for GABA-A receptor potentiation by neuroactive steroids.Non-stereo-selective cytosolic human brain tissue 3-ketosteroid reductase is refractory to inhibition by AKR1C inhibitors.A neurosteroid analogue photolabeling reagent labels the colchicine-binding site on tubulin: a mass spectrometric analysis.A new look at the 5alpha-reductase inhibitor finasteride.11-Deoxycortisol impedes GABAergic neurotransmission and induces drug-resistant status epilepticus in mice.Hormones, nicotine, and cocaine: clinical studies.Treatment with and withdrawal from finasteride alter ethanol intake patterns in male C57BL/6J mice: potential role of endogenous neurosteroids?Neurosteroid modulators of GABA(A) receptors differentially modulate Ethanol intake patterns in male C57BL/6J miceSpecific GABA(A) agonists and partial agonists.Residues in the first transmembrane domain of the Caenorhabditis elegans GABA(A) receptor confer sensitivity to the neurosteroid pregnenolone sulfate.Synthetic neurosteroids on brain protectionAlteration of ethanol drinking in mice via modulation of the GABA(A) receptor with ganaxolone, finasteride, and gaboxadol.Sex Differences in Ethanol's Anxiolytic Effect and Chronic Ethanol Withdrawal Severity in Mice with a Null Mutation of the 5α-Reductase Type 1 Gene.The role of progestins in the behavioral effects of cocaine and other drugs of abuse: human and animal research.Effects of pregnanolone and flunitrazepam on the retention of response sequences in rats.Sex differences in the effect of finasteride on acute ethanol withdrawal severity in C57BL/6J and DBA/2J mice.Neurosteroids and GABA-A Receptor Function.A 17beta-derivative of allopregnanolone is a neurosteroid antagonist at a cerebellar subpopulation of GABA A receptors with nanomolar affinity.Mechanisms of neurosteroid interactions with GABA(A) receptors.Effect of ganaxolone and THIP on operant and limited-access ethanol self-administration.Ethanol intake patterns in female mice: influence of allopregnanolone and the inhibition of its synthesis.Sigma receptors [σRs]: biology in normal and diseased statesThe neurosteroid environment in the hippocampus exerts bi-directional effects on seizure susceptibility in miceDifferential effects of allopregnanolone on the escalation of cocaine self-administration and sucrose intake in female rats.Ischemic insult to cerebellar Purkinje cells causes diminished GABAA receptor function and allopregnanolone neuroprotection is associated with GABAA receptor stabilization.The influence of neuroactive steroid lipophilicity on GABAA receptor modulation: evidence for a low-affinity interaction.Selected line difference in the effects of ethanol dependence and withdrawal on allopregnanolone levels and 5alpha-reductase enzyme activity and expression.The influence of the membrane on neurosteroid actions at GABA(A) receptors.Inhibition of 5alpha-reduced steroid biosynthesis impedes acquisition of ethanol drinking in male C57BL/6J mice.Increased expression of the neuropeptide Y receptor Y(1) gene in the medial amygdala of transgenic mice induced by long-term treatment with progesterone or allopregnanolone.New neuronal networks involved in ethanol reinforcement.
P2860
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P2860
Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Neuroactive steroids: potentia ...... cal and psychiatric disorders.
@ast
Neuroactive steroids: potentia ...... cal and psychiatric disorders.
@en
type
label
Neuroactive steroids: potentia ...... cal and psychiatric disorders.
@ast
Neuroactive steroids: potentia ...... cal and psychiatric disorders.
@en
prefLabel
Neuroactive steroids: potentia ...... cal and psychiatric disorders.
@ast
Neuroactive steroids: potentia ...... cal and psychiatric disorders.
@en
P2093
P1476
Neuroactive steroids: potentia ...... cal and psychiatric disorders.
@en
P2093
P304
P356
10.1016/S0165-6147(99)01318-8
P577
1999-03-01T00:00:00Z