Persistent infection of human pancreatic islets by coxsackievirus B is associated with alpha interferon synthesis in beta cells.
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The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3Mechanisms of Beta Cell Dysfunction Associated With Viral InfectionHow Does Thymus Infection by Coxsackievirus Contribute to the Pathogenesis of Type 1 Diabetes?Potential viral pathogenic mechanism in human type 1 diabetesLocalization of nucleic acid-sensing toll-like receptors in human and mouse pancreas.Viral protein VP4 is a target of human antibodies enhancing coxsackievirus B4- and B3-induced synthesis of alpha interferonGroup B coxsackievirus diabetogenic phenotype correlates with replication efficiency.Environmental factors in the etiology of type 1 diabetes.IFIH1-GCA-KCNH7 locus: influence on multiple sclerosis risk.Type I diabetes mellitus: genetic factors and presumptive enteroviral etiology or protection.Expression of innate immunity genes and damage of primary human pancreatic islets by epidemic strains of Echovirus: implication for post-virus islet autoimmunity.Viral infection of engrafted human islets leads to diabetes.Rotavirus infection of infant and young adult nonobese diabetic mice involves extraintestinal spread and delays diabetes onset.New Insights into the Understanding of Hepatitis C Virus Entry and Cell-to-Cell Transmission by Using the Ionophore Monensin A.Persistent infection of thymic epithelial cells with coxsackievirus B4 results in decreased expression of type 2 insulin-like growth factorCoxsackievirus infections and NOD mice: relevant models of protection from, and induction of, type 1 diabetes.Human astrocytic cells support persistent coxsackievirus B3 infection.Pathogenesis of coxsackievirus-B5 acquired from intra-renal porcine islet cell xenografts in diabetic mice.Coxsackievirus B4 infection of human fetal thymus cellsViruses and Type 1 diabetes: a dynamic labile equilibrium.Viral infections in type 1 diabetes mellitus--why the β cells?Enteroviruses in the pathogenesis of type 1 diabetes.Immunopathology of the human pancreas in type-I diabetes.Group B coxsackieviruses and autoimmunity: focus on Type 1 diabetes.Viruses and type 1 diabetes: a new look at an old story.Death waits for no man--does it wait for a virus? How enteroviruses induce and control cell deathLessons from the mouse: potential contribution of bystander lymphocyte activation by viruses to human type 1 diabetes.Differential effects of three echovirus strains on cell lysis and insulin secretion in beta cell derived lines.Enteroviral proteases: structure, host interactions and pathogenicity.Receptor for Advanced Glycation End Products (RAGE) in Type 1 Diabetes Pathogenesis.MicroRNAs in Type 1 Diabetes: Complex Interregulation of the Immune System, β Cell Function and Viral Infections.Coxsackievirus B4 can infect human pancreas ductal cells and persist in ductal-like cell cultures which results in inhibition of Pdx1 expression and disturbed formation of islet-like cell aggregates.Persistent infection of human thymic epithelial cells by coxsackievirus B4.Persistence of Coxsackievirus B4 in pancreatic ductal-like cells results in cellular and viral changes.Detection of enteroviruses in stools precedes islet autoimmunity by several months: possible evidence for slowly operating mechanisms in virus-induced autoimmunity.Coxsackievirus B3 replication and persistence in intestinal cells from mice infected orally and in the human CaCo-2 cell line.Monocytes of Patients with Type 1 Diabetes Harbour Enterovirus RNA.Molecular analysis of an echovirus 3 strain isolated from an individual concurrently with appearance of islet cell and IA-2 autoantibodies.Murine pancreatic beta TC3 cells show greater 2', 5'-oligoadenylate synthetase (2'5'AS) antiviral enzyme activity and apoptosis following IFN-alpha or poly(I:C) treatment than pancreatic alpha TC3 cells.A single amino acid substitution in viral VP1 protein alters the lytic potential of clone-derived variants of echovirus 9 DM strain in human pancreatic islets.
P2860
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P2860
Persistent infection of human pancreatic islets by coxsackievirus B is associated with alpha interferon synthesis in beta cells.
description
2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Persistent infection of human ...... feron synthesis in beta cells.
@ast
Persistent infection of human ...... feron synthesis in beta cells.
@en
type
label
Persistent infection of human ...... feron synthesis in beta cells.
@ast
Persistent infection of human ...... feron synthesis in beta cells.
@en
prefLabel
Persistent infection of human ...... feron synthesis in beta cells.
@ast
Persistent infection of human ...... feron synthesis in beta cells.
@en
P2093
P2860
P1433
P1476
Persistent infection of human ...... feron synthesis in beta cells.
@en
P2093
P2860
P304
10153-10164
P356
10.1128/JVI.74.21.10153-10164.2000
P577
2000-11-01T00:00:00Z