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Maintenance of β-cell maturity and plasticity in the adult pancreas: developmental biology concepts in adult physiologyPhase transitions in the multi-cellular regulatory behavior of pancreatic islet excitabilityHomologous and heterologous asynchronicity between identified alpha-, beta- and delta-cells within intact islets of Langerhans in the mouse.Persistent infection of human pancreatic islets by coxsackievirus B is associated with alpha interferon synthesis in beta cells.Why pancreatic islets burst but single beta cells do not. The heterogeneity hypothesisThe G protein-coupled receptor P2Y14 influences insulin release and smooth muscle function in mice.A reappraisal of the blood glucose homeostat which comprehensively explains the type 2 diabetes mellitus-syndrome X complex.A low-oxygenated subpopulation of pancreatic islets constitutes a functional reserve of endocrine cells.Increased secretory demand rather than a defect in the proinsulin conversion mechanism causes hyperproinsulinemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus.Accumulation of extracellular matrix and developmental dysregulation in the pancreas by transgenic production of transforming growth factor-beta 1.Concise Review: Markers for Assessing Human Stem Cell-Derived Implants as β-Cell Replacement in Type 1 Diabetes.Decreases in Gap Junction Coupling Recovers Ca2+ and Insulin Secretion in Neonatal Diabetes Mellitus, Dependent on Beta Cell Heterogeneity and NoiseKin of IRRE-like Protein 2 Is a Phosphorylated Glycoprotein That Regulates Basal Insulin Secretion.Exploring functional beta-cell heterogeneity in vivo using PSA-NCAM as a specific marker.Protein-mediated interactions of pancreatic islet cellsGlucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program.Single pancreatic beta cells co-express multiple islet hormone genes in mice.Activity-dependent mobilization of the adhesion molecule polysialic NCAM to the cell surface of neurons and endocrine cells.Decreasing cx36 gap junction coupling compensates for overactive KATP channels to restore insulin secretion and prevent hyperglycemia in a mouse model of neonatal diabetes.Evidence for Loss in Identity, De-Differentiation, and Trans-Differentiation of Islet β-Cells in Type 2 Diabetes.Connexins: key mediators of endocrine function.Impact of islet architecture on β-cell heterogeneity, plasticity and function.Single-Cell Transcriptomics of the Human Endocrine Pancreas.Targeting insulin-producing beta cells for regenerative therapy.Dimensionality and size scaling of coordinated Ca(2+) dynamics in MIN6 β-cell clusters.Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans.Beta cell heterogeneity: an evolving concept.Bone marrow: an extra-pancreatic hideout for the elusive pancreatic stem cell?Prolonged exposure of human beta cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation.A GFP-based screen for growth-arrested, recombinant protein-producing cells.Mammalian glucokinase and its gene.Heterogeneity in glucose sensitivity among pancreatic beta-cells is correlated to differences in glucose phosphorylation rather than glucose transport.The relationship between receptor-effector unit heterogeneity and the shape of the concentration-effect profile: pharmacodynamic implications.Contributions of modeling to understanding stimulus-secretion coupling in pancreatic beta-cells.Heterogeneity in the Beta-Cell Population: a Guided Search Into Its Significance in Pancreas and in Implants.Interrogating islets in health and disease with single-cell technologiesGap junctions and other mechanisms of cell-cell communication regulate basal insulin secretion in the pancreatic islet.Expression of the protein tyrosine phosphatase-like protein IA-2 during pancreatic islet development.Isolated mouse pancreatic beta-cells show cell-specific temporal response pattern.Measurements of insulin responses as predictive markers of pancreatic beta-cell mass in normal and beta-cell-reduced lean and obese Göttingen minipigs in vivo.
P2860
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P2860
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Heterogeneity in pancreatic beta-cell population.
@ast
Heterogeneity in pancreatic beta-cell population.
@en
type
label
Heterogeneity in pancreatic beta-cell population.
@ast
Heterogeneity in pancreatic beta-cell population.
@en
prefLabel
Heterogeneity in pancreatic beta-cell population.
@ast
Heterogeneity in pancreatic beta-cell population.
@en
P356
P1433
P1476
Heterogeneity in pancreatic beta-cell population.
@en
P2093
Pipeleers DG
P304
P356
10.2337/DIAB.41.7.777
P407
P577
1992-07-01T00:00:00Z