Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes.
about
Structure and expression of the TREX1 and TREX2 3' --> 5' exonuclease genesCritical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpointThe human checkpoint sensor and alternative DNA clamp Rad9-Rad1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machineryInteraction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cellsProteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stressThe HHpred interactive server for protein homology detection and structure predictionLoading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitroChl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathwayPhosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damagePurification and characterization of human DNA damage checkpoint Rad complexesHuman checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cellsMolecular modeling-based analysis of interactions in the RFC-dependent clamp-loading processRegulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatinGerminating fission yeast spores delay in G1 in response to UV irradiationFission yeast Rad26 responds to DNA damage independently of Rad3mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationshipsBiochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNAHuman RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double strand breaksStructures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and openingStructure and Functional Implications of the Human Rad9-Hus1-Rad1 Cell Cycle Checkpoint ComplexA Structural Hinge in Eukaryotic MutY Homologues Mediates Catalytic Activity and Rad9–Rad1–Hus1 Checkpoint Complex InteractionsActivation of the S-phase checkpoint inhibits degradation of the F-box protein Dia2ELG1, a yeast gene required for genome stability, forms a complex related to replication factor CSaccharomyces cerevisiae CTF18 and CTF4 are required for sister chromatid cohesionDpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repairYeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.A role for Ddc1 in signaling meiotic double-strand breaks at the pachytene checkpoint.RPA-like proteins mediate yeast telomere function.Characterization of DNA damage-stimulated self-interaction of Saccharomyces cerevisiae checkpoint protein Rad17p.Recovery from the DNA Replication CheckpointPCNA interacts with hHus1/hRad9 in response to DNA damage and replication inhibitionReconstitution and molecular analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA damage responsive checkpoint complexATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responsesStructures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low voltage microscopyA role of the C-terminal region of human Rad9 (hRad9) in nuclear transport of the hRad9 checkpoint complexNFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage responseRecruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phaseThe Caenorhabditis elegans homolog of Gen1/Yen1 resolvases links DNA damage signaling to DNA double-strand break repairMutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombinationATR pathway is the primary pathway for activating G2/M checkpoint induction after re-replication.
P2860
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P2860
Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes.
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Structure-based predictions of ...... p and clamp-loading complexes.
@ast
Structure-based predictions of ...... p and clamp-loading complexes.
@en
type
label
Structure-based predictions of ...... p and clamp-loading complexes.
@ast
Structure-based predictions of ...... p and clamp-loading complexes.
@en
prefLabel
Structure-based predictions of ...... p and clamp-loading complexes.
@ast
Structure-based predictions of ...... p and clamp-loading complexes.
@en
P2860
P356
P1476
Structure-based predictions of ...... p and clamp-loading complexes.
@en
P2093
C Venclovas
M P Thelen
P2860
P304
P356
10.1093/NAR/28.13.2481
P407
P577
2000-07-01T00:00:00Z