Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a- and Arf-independent manner.
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Impact of recent innovations in the use of mass cytometry in support of drug developmentAcute systemic DNA damage in youth does not impair immune defense with agingPU.1 downregulation in murine radiation-induced acute myeloid leukaemia (AML): from molecular mechanism to human AMLLoss of P2Y₁₄ results in an arresting response to hematological stressClearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in miceSensitivity and dose dependency of radiation-induced injury in hematopoietic stem/progenitor cells in mice.Innate immune activation by tissue injury and cell death in the setting of hematopoietic stem cell transplantation.ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice.Non-Lethal Ionizing Radiation Promotes Aging-Like Phenotypic Changes of Human Hematopoietic Stem and Progenitor Cells in Humanized Mice.Excessive proliferation and impaired function of primitive hematopoietic cells in bone marrow due to senescence post chemotherapy in a T cell acute lymphoblastic leukemia model.Low Doses of Oxygen Ion Irradiation Cause Acute Damage to Hematopoietic Cells in Mice.p16INK4A expression is frequently increased in periorbital and ocular squamous lesions.The Delayed Effects of Acute Radiation Syndrome: Evidence of Long-Term Functional Changes in the Clonogenic Cells of the Small IntestineGranulocyte colony-stimulating factor exacerbates hematopoietic stem cell injury after irradiationSerum microRNAs are early indicators of survival after radiation-induced hematopoietic injury.Stem Cell-Specific Mechanisms Ensure Genomic Fidelity within HSCs and upon Aging of HSCs.HSC Aging and Senescent Immune Remodeling.SIP1 is a downstream effector of GADD45G in senescence induction and growth inhibition of liver tumor cells.p38 MAPK Inhibitor Insufficiently Attenuates HSC Senescence Administered Long-Term after 6 Gy Total Body Irradiation in MiceDeinococcus radiodurans pprI expression enhances the radioresistance of eukaryotes.Hematopoietic Stem Cells from Ts65Dn Mice Are Deficient in the Repair of DNA Double-Strand Breaks.Cell cycle of primitive hematopoietic progenitors decelerated in senescent mice is reactively accelerated after 2-Gy whole-body irradiationWhole-body proton irradiation causes long-term damage to hematopoietic stem cells in mice.Ionizing Radiation-Induced Endothelial Cell Senescence and Cardiovascular Diseases.Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms.DNA-damage response in hematopoietic stem cells: an evolutionary trade-off between blood regeneration and leukemia suppression.HSC senescence upon irradiation.Effects of thermal water inhalation in chronic upper respiratory tract infections in elderly and young patients.Sublethal Total Body Irradiation Causes Long-Term Deficits in Thymus Function by Reducing Lymphoid Progenitors.Hhex Regulates Hematopoietic Stem Cell Self-Renewal and Stress Hematopoiesis via Repression of Cdkn2a.Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury.The mechanism for the radioprotective effects of zymosan-A in mice.Multiplacenta derived stem cell/cytokine treatment increases survival time in a mouse model with radiation-induced bone marrow damage.The triterpenoid RTA 408 is a robust mitigator of hematopoietic acute radiation syndrome in mice.Wip1 deficiency impairs haematopoietic stem cell function via p53 and mTORC1 pathways.Thrombopoietin protects hematopoietic stem cells from retrotransposon-mediated damage by promoting an antiviral response.Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation.Ionizing Radiation-Induced Cellular Senescence in Normal, Non-transformed Cells and the Involved DNA Damage Response: A Mini Review.The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow.Inhibition of mTORC1 signaling protects kidney from irradiation-induced toxicity via accelerating recovery of renal stem-like cells
P2860
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P2860
Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a- and Arf-independent manner.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Total body irradiation causes ...... a- and Arf-independent manner.
@ast
Total body irradiation causes ...... a- and Arf-independent manner.
@en
type
label
Total body irradiation causes ...... a- and Arf-independent manner.
@ast
Total body irradiation causes ...... a- and Arf-independent manner.
@en
prefLabel
Total body irradiation causes ...... a- and Arf-independent manner.
@ast
Total body irradiation causes ...... a- and Arf-independent manner.
@en
P2093
P2860
P1433
P1476
Total body irradiation causes ...... a- and Arf-independent manner.
@en
P2093
Aimin Meng
Daohong Zhou
David Gardner
Hongliang Li
Lijian Shao
Lingbo Liu
P2860
P304
P356
10.1182/BLOOD-2013-07-515619
P407
P577
2014-03-12T00:00:00Z