The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytes.
about
Structural Comparison of Allogeneic and Syngeneic T Cell Receptor–Peptide-Major Histocompatibility Complex ComplexesThe contributions of mass spectrometry to understanding of immune recognition by T lymphocytes.Breast and other cancer dormancy as a therapeutic endpoint: speculative recombinant T cell receptor ligand (RTL) adjuvant therapy worth considering?In vitro evolution of a T cell receptor with high affinity for peptide/MHC.Why don't CD8+ T cells reduce the lifespan of SIV-infected cells in vivo?Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function.Chlamydia spp. development is differentially altered by treatment with the LpxC inhibitor LPC-011.The impact of TCR-binding properties and antigen presentation format on T cell responsiveness.Killing of targets by CD8 T cells in the mouse spleen follows the law of mass action.Fast on-rates allow short dwell time ligands to activate T cells.Discrepancy between ELISPOT IFN-gamma secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-lifeRetargeting NK92 cells using an HLA-A2-restricted, EBNA3C-specific chimeric antigen receptor.Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor.Dependence of lymphopenia-induced T cell proliferation on the abundance of peptide/ MHC epitopes and strength of their interaction with T cell receptors.Soluble peptide-MHC monomers cause activation of CD8+ T cells through transfer of the peptide to T cell MHC molecules.Modulation of CD4 T cell function by soluble MHC II-peptide chimeras.CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics.The tumor targeted superantigen ABR-217620 selectively engages TRBV7-9 and exploits TCR-pMHC affinity mimicry in mediating T cell cytotoxicity.Suppression of human glioma xenografts with second-generation IL13R-specific chimeric antigen receptor-modified T cells.Breaking the affinity ceiling for antibodies and T cell receptorsEffects of complementarity determining region mutations on the affinity of an alpha/beta T cell receptor: measuring the energy associated with CD4/CD8 repertoire skewingCD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation.A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex.Lysis of HIV-1-infected cells and inhibition of viral replication by universal receptor T cells.Antigen sensitivity of CD22-specific chimeric TCR is modulated by target epitope distance from the cell membrane.Second-generation anti-carcinoembryonic antigen designer T cells resist activation-induced cell death, proliferate on tumor contact, secrete cytokines, and exhibit superior antitumor activity in vivo: a preclinical evaluation.One example on how colloidal nano- and microparticles could contribute to medicine.Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes.Optimal viral immune surveillance evasion strategiesProtein kinase C theta regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL.BCR-ABL fusion regions as a source of multiple leukemia-specific CD8+ T-cell epitopes.Role of the T cell receptor ligand affinity in T cell activation by bacterial superantigens.Multi-epitope DNA vaccines.Strategic mutations in the class I major histocompatibility complex HLA-A2 independently affect both peptide binding and T cell receptor recognition.Are we immune by chance?Modulation of Naive CD8 T Cell Response Features by Ligand Density, Affinity, and Continued Signaling via Internalized TCRs.The challenges of solid tumor for designer CAR-T therapies: a 25-year perspective.Formation of TCR dimers/trimers as a crucial step for T cell activation.Altered superantigenic ligands demonstrate the quantitative nature of T-cell activation.A Response Calculus for Immobilized T Cell Receptor Ligands
P2860
Q27638941-E5CF2797-5E01-4AD2-824B-F17A003C12A4Q30444065-51C97B65-DD4A-41F0-827B-DAF583A897B2Q30495334-89347692-088C-4827-91E6-A0314B2FCBD3Q30861962-C3FADC4D-2758-4EBD-8EC7-B9744A488B7CQ31032227-4D35AD8C-560E-4B7F-8518-E588C2ADCA38Q33229925-01A0B3C5-6865-4BD1-8C9E-F3761E68DB52Q33595583-B3286935-1045-48A8-B8CB-16756932A6ACQ33737674-A8B9D99F-3839-47B4-B0D2-B33FFBA38E79Q33808927-8BFDB7E0-2249-4106-9574-3E0A4C8E0EA1Q33928549-B1DC4CD5-2DD8-487D-82D9-4A9312B1D1FFQ33943148-834F2D74-C474-4295-A866-A493C7D0DABBQ34042430-7AD58ABB-5712-4C32-B046-BF9A941877ACQ34099738-BE6AEFBA-F1B0-460E-AEFB-7E485560E285Q34100049-3A93E674-3F7D-42C2-85F4-D49B60D39863Q34160808-AFBC5285-8036-4665-AD6F-E948C582D7F9Q34560511-E161B2EB-8603-4B5A-8F50-B0465123FA0AQ34738334-A6768654-F39B-4B92-94B0-AAF551822ED5Q35032671-B4447AB9-3ECC-4AF6-8EFB-D4F437D4A804Q35111932-52EE4F44-9BE6-400D-A527-0DB376B1DB2DQ36113815-6CB794FE-8A68-4C47-8294-E28BB4793E81Q36367702-59B34551-B490-44F0-BFB0-9023A60F2915Q36369627-A456DD0C-79C1-4D4B-9D8E-5B2728E49EEFQ36369989-535F832E-B367-4ADA-A987-57C945001907Q36598618-CAE9489B-05C3-4BDE-BC6D-5A52D3D669C5Q36979111-6A421D36-9DA7-457B-8775-1ADAD2DE6C0BQ37137406-1E25E12E-5A83-4569-A913-CA3442C36634Q37643744-3F126A48-70D8-4DCD-AF49-A61DC8B2B1CEQ37953322-930A1419-E5E3-466A-8959-1D91A060B1A7Q39166782-ACEC1808-7355-412C-AE52-BD4C87042CD5Q39938289-6D0D9976-75C9-4462-913B-D370A5A7E5B1Q40239641-601F574A-A3DC-4749-B0E2-45FD919AA846Q40800278-8CCFE994-316B-4818-B650-375662F45A71Q41604754-727B6D1E-FF19-4469-A35C-4077AC903670Q44886665-E3871146-A225-44A3-8432-EFECD34E3E30Q47131906-7384F4AD-A1A4-41E5-BDDC-0E54FA6767B6Q48338497-A231D2FE-DCAC-405A-A128-5383AC2DC6E8Q50033731-FA6FD28C-925F-4F82-AFC8-EA5C0F7B86FCQ52237316-DF2821FF-3D3E-4013-81F1-3F53C640E6C5Q53805171-062898D8-026D-4880-ACEC-1719F734166BQ56112100-5F4ED2F6-199B-440A-87A8-F558F8590274
P2860
The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytes.
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The law of mass action governs ...... CD8+ cytotoxic T lymphocytes.
@ast
The law of mass action governs ...... CD8+ cytotoxic T lymphocytes.
@en
type
label
The law of mass action governs ...... CD8+ cytotoxic T lymphocytes.
@ast
The law of mass action governs ...... CD8+ cytotoxic T lymphocytes.
@en
prefLabel
The law of mass action governs ...... CD8+ cytotoxic T lymphocytes.
@ast
The law of mass action governs ...... CD8+ cytotoxic T lymphocytes.
@en
P2093
P2860
P356
P1476
The law of mass action governs ...... CD8+ cytotoxic T lymphocytes.
@en
P2093
P2860
P304
11990-11992
P356
10.1073/PNAS.92.26.11990
P407
P577
1995-12-01T00:00:00Z