Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones.
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Structural and Mechanical Improvements to Bone Are Strain Dependent with Axial Compression of the Tibia in Female C57BL/6 MiceIn silico bone mechanobiology: modeling a multifaceted biological systemLoad-induced changes in bone stiffness and cancellous and cortical bone mass following tibial compression diminish with age in female miceTrabecular evidence for a human-like gait in Australopithecus africanusTrabecular bone scales allometrically in mammals and birdsParathyroid hormone's enhancement of bones' osteogenic response to loading is affected by ageing in a dose- and time-dependent manner.Bone marrow changes related to disuse.Healing of non-displaced fractures produced by fatigue loading of the mouse ulna.Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuseAndrogen receptor (AR) in osteocytes is important for the maintenance of male skeletal integrity: evidence from targeted AR disruption in mouse osteocytes.Differential gene expression from microarray analysis distinguishes woven and lamellar bone formation in the rat ulna following mechanical loading.The Contribution of Experimental in vivo Models to Understanding the Mechanisms of Adaptation to Mechanical Loading in BoneBone density and neuromuscular function in older competitive athletes depend on running distance.Increase of Compact Bone Thickness in Rat Tibia after Implanting MgO into the Bone Marrow Cavity.Short-term low-strain vibration enhances chemo-transport yet does not stimulate osteogenic gene expression or cortical bone formation in adult miceMechanical loading-related bone gain is enhanced by tamoxifen but unaffected by fulvestrant in female miceAge-related impairment of bones' adaptive response to loading in mice is associated with sex-related deficiencies in osteoblasts but no change in osteocytes.Murine TMJ loading causes increased proliferation and chondrocyte maturation.Risedronate does not reduce mechanical loading-related increases in cortical and trabecular bone mass in miceAged mice have enhanced endocortical response and normal periosteal response compared with young-adult mice following 1 week of axial tibial compression.Systemic effects of ulna loading in male rats during functional adaptationTibial compression is anabolic in the adult mouse skeleton despite reduced responsiveness with aging.Cortical bone resorption following muscle paralysis is spatially heterogeneous.Loading-related regulation of transcription factor EGR2/Krox-20 in bone cells is ERK1/2 protein-mediated and prostaglandin, Wnt signaling pathway-, and insulin-like growth factor-I axis-dependentWnt16 Is Associated with Age-Related Bone Loss and Estrogen Withdrawal in Murine Bone.Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered.In vivo axial loading of the mouse tibia.Disuse rescues the age-impaired adaptive response to external loading in miceBones' adaptive response to mechanical loading is essentially linear between the low strains associated with disuse and the high strains associated with the lamellar/woven bone transition.Mechanical Loading Attenuates Radiation-Induced Bone Loss in Bone Marrow Transplanted MicePhospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing.Exercise does not enhance aged bone's impaired response to artificial loading in C57Bl/6 mice.Preclinical mouse models for assessing axial compression of long bones during exercise.Cortical and trabecular bone adaptation to incremental load magnitudes using the mouse tibial axial compression loading model.The cyclooxygenase-2 selective inhibitor NS-398 does not influence trabecular or cortical bone gain resulting from repeated mechanical loading in female miceEstrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2.Male mice housed in groups engage in frequent fighting and show a lower response to additional bone loading than females or individually housed males that do not fight.Fam3c modulates osteogenic cell differentiation and affects bone volume and cortical bone mineral densitySport-specific association between exercise loading and the density, geometry, and microstructure of weight-bearing bone in young adult men.Transcriptional profiling of cortical versus cancellous bone from mechanically-loaded murine tibiae reveals differential gene expression.
P2860
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P2860
Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones.
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Functional adaptation to mecha ...... confined to the loaded bones.
@ast
Functional adaptation to mecha ...... confined to the loaded bones.
@en
type
label
Functional adaptation to mecha ...... confined to the loaded bones.
@ast
Functional adaptation to mecha ...... confined to the loaded bones.
@en
prefLabel
Functional adaptation to mecha ...... confined to the loaded bones.
@ast
Functional adaptation to mecha ...... confined to the loaded bones.
@en
P2860
P1433
P1476
Functional adaptation to mecha ...... confined to the loaded bones.
@en
P2093
Joanna S Price
Lance E Lanyon
P2860
P304
P356
10.1016/J.BONE.2009.08.054
P577
2009-09-03T00:00:00Z