PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice. - Wikidata - wikimedia - TriplyDB

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.

http://www.wikidata.org/entity/Q33685586

about

Region-specific deletions of RIM1 reproduce a subset of global RIM1α(-/-) phenotypes Central nervous system mechanisms linking the consumption of palatable high-fat diets to the defense of greater adiposity Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals Physiology of leptin: energy homeostasis, neuroendocrine function and metabolism Leptin signaling and leptin resistance Central nervous control of energy and glucose balance: focus on the central melanocortin system Over-expression of leptin receptors in hypothalamic POMC neurons increases susceptibility to diet-induced obesity Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy.Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis.A treasure trove of hypothalamic neurocircuitries governing body weight homeostasis Novel role for SHP-2 in nutrient-responsive control of S6 kinase 1 signaling.Leptin revisited: its mechanism of action and potential for treating diabetes.Treatment with Panax ginseng antagonizes the estrogen decline in ovariectomized mice.Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia.Metabolic regulation by protein tyrosine phosphatases.Disruption of protein-tyrosine phosphatase 1B expression in the pancreas affects β-cell function.Treatment with qibaomeiran, a kidney-invigorating Chinese herbal formula, antagonizes estrogen decline in ovariectomized rats Ventromedial hypothalamus-specific Ptpn1 deletion exacerbates diet-induced obesity in female mice.Minireview: Inflammation and obesity pathogenesis: the hypothalamus heats up.Induction of leptin resistance by activation of cAMP-Epac signaling.Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis.Ghrelin induces leptin resistance by activation of suppressor of cytokine signaling 3 expression in male rats: implications in satiety regulation Leptin signaling.20 years of leptin: connecting leptin signaling to biological function Obesity and leptin resistance: distinguishing cause from effect.Enhanced leptin sensitivity, reduced adiposity, and improved glucose homeostasis in mice lacking exchange protein directly activated by cyclic AMP isoform 1 New pharmacological perspectives for the leptin receptor in the treatment of obesity Cyclic AMP sensor EPAC proteins and energy homeostasis.Pre- and postnatal calorie restriction perturbs early hypothalamic neuropeptide and energy balance.LEOPARD syndrome-associated SHP2 mutation confers leanness and protection from diet-induced obesity An obligate role of oxytocin neurons in diet induced energy expenditure Protein-tyrosine phosphatase 1B (PTP1B) is a novel regulator of central brain-derived neurotrophic factor and tropomyosin receptor kinase B (TrkB) signaling Chronic sleep fragmentation during the sleep period induces hypothalamic endoplasmic reticulum stress and PTP1b-mediated leptin resistance in male mice.Shp2 signaling in POMC neurons is important for leptin's actions on blood pressure, energy balance, and glucose regulation Protein tyrosine phosphatase-1B contributes to LPS-induced leptin resistance in male rats Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposure.Current and future drug targets in weight management Melanocortin control of energy balance: evidence from rodent models.Protein tyrosine phosphatase-1B modulates pancreatic β-cell mass Hypothalamic inflammation: a double-edged sword to nutritional diseases.

P2860

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P2860

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.

http://www.wikidata.org/entity/Q33685586

description

2010 nî lūn-bûn

@nan

2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

@zh-hans

2010年学术文章

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2010年学术文章

@zh-sg

2010年學術文章

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name

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.

@ast

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.

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type

label

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.

@ast

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.

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prefLabel

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.

@ast

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.

@en

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PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.

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Bart C De Jonghe

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Derek Zimmer

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Kimberly Rak

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Marybless Atienza

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Ryoichi Banno

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Wentian Yang

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P2860

TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B

PTP1B regulates leptin signal transduction in vivo

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

From observation to experimentation: leptin action in the mediobasal hypothalamus

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

Central melanocortin receptors regulate insulin action

Endogenous glucose production is inhibited by the adipose-derived protein Acrp30

Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism

SHP-2 mediates target-regulated axonal termination and NGF-dependent neurite growth in sympathetic neurons

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