Cloning of neuronal mtDNA variants in cultured cells by synaptosome fusion with mtDNA-less cells.
about
Absence of pathogenic mitochondrial DNA mutations in mouse brain tumorsCytoplasmic hybrid (cybrid) cell lines as a practical model for mitochondriopathiesProduction of transmitochondrial cybrids containing naturally occurring pathogenic mtDNA variants.The age-related accumulation of a mitochondrial DNA control region mutation in muscle, but not brain, detected by a sensitive PNA-directed PCR clamping based method.Mutations in BALB mitochondrial DNA induce CCL20 up-regulation promoting tumorigenic phenotypesMitochondrial defects in neurodegenerative disease.Neuronal and astrocyte dysfunction diverges from embryonic fibroblasts in the Ndufs4fky/fky mouse.Somatic alterations in mitochondrial DNA produce changes in cell growth and metabolism supporting a tumorigenic phenotype.An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copperII.Identification of an mtDNA mutation hot spot in UV-induced mouse skin tumors producing altered cellular biochemistry.Maternal germ-line transmission of mutant mtDNAs from embryonic stem cell-derived chimeric mice.Revisiting the mouse mitochondrial DNA sequenceProduction of homoplasmic xenomitochondrial miceAlzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replicationMouse models of oxidative phosphorylation dysfunction and diseaseThe pathophysiology of mitochondrial disease as modeled in the mouse.Incompatibility of nucleus and mitochondria causes xenomitochondrial cybrid unviable across human, mouse, and pig cells.Expression of Rattus norvegicus mtDNA in Mus musculus cells results in multiple respiratory chain defects.Quantitative control of mitochondria transfer between live single cells using a microfluidic device.Capture of somatic mtDNA point mutations with severe effects on oxidative phosphorylation in synaptosome cybrid clones from human brain.Cybrid Models of Pathological Cell Processes in Different Diseases.
P2860
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P2860
Cloning of neuronal mtDNA variants in cultured cells by synaptosome fusion with mtDNA-less cells.
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Cloning of neuronal mtDNA vari ...... fusion with mtDNA-less cells.
@ast
Cloning of neuronal mtDNA vari ...... fusion with mtDNA-less cells.
@en
type
label
Cloning of neuronal mtDNA vari ...... fusion with mtDNA-less cells.
@ast
Cloning of neuronal mtDNA vari ...... fusion with mtDNA-less cells.
@en
prefLabel
Cloning of neuronal mtDNA vari ...... fusion with mtDNA-less cells.
@ast
Cloning of neuronal mtDNA vari ...... fusion with mtDNA-less cells.
@en
P2093
P2860
P356
P1476
Cloning of neuronal mtDNA vari ...... fusion with mtDNA-less cells.
@en
P2093
D C Wallace
J Schmiedel
S Hosseini
P2860
P304
P356
10.1093/NAR/28.10.2164
P407
P577
2000-05-01T00:00:00Z