Detection of a specific mitochondrial DNA deletion in tissues of older humans.
about
Oxidative stress, mitochondrial dysfunction, and agingAn autosomal locus predisposing to multiple deletions of mtDNA on chromosome 3pMitophagy plays a central role in mitochondrial ageingMitochondrial DNA damage patterns and aging: revising the evidences for humans and miceSomatic mutations in aging, cancer and neurodegenerationMechanism of homologous recombination and implications for aging-related deletions in mitochondrial DNAReduced adolescent-age spatial learning ability associated with elevated juvenile-age superoxide levels in complex I mouse mutantsThe Role of the Transcription Factor Foxo3 in Hearing Maintenance: Informed Speculation on a New Player in the CochleaMitochondria-ros crosstalk in the control of cell death and agingMitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator miceA mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicineMitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: analysis by laser-capture microdissection.Mitochondrial DNA deletion mutations and sarcopenia.Accumulation of mitochondrial DNA deletion mutations in aged muscle fibers: evidence for a causal role in muscle fiber lossMitochondrial DNA and primary mitochondrial dysfunction in Parkinson's disease.Correlation of the 4977 bp mitochondrial DNA deletion with human sperm dysfunction.Cloning of neuronal mtDNA variants in cultured cells by synaptosome fusion with mtDNA-less cells.Mitochondrial medicine--recent advances.Mitochondrial mutational spectra in human cells and tissues.Paravertebral muscles in disease of the cervical spineTargeted enrichment and high-resolution digital profiling of mitochondrial DNA deletions in human brain.Mitochondrial genome maintenance in health and disease.The age-related accumulation of a mitochondrial DNA control region mutation in muscle, but not brain, detected by a sensitive PNA-directed PCR clamping based method.Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.Susceptibility to Calcium Dysregulation during Brain Aging.Two novel pathogenic mitochondrial DNA mutations affecting organelle number and protein synthesis. Is the tRNA(Leu(UUR)) gene an etiologic hot spot?Increased leukocyte mitochondrial DNA copy number is associated with oral premalignant lesions: an epidemiology study.Progress and prospects in human genetic research into age-related hearing impairment.The frequency of heteroplasmy in the HVII region of mtDNA differs across tissue types and increases with age.Maternally transmitted mitochondrial DNA mutations can reduce lifespanDeceleration of fusion-fission cycles improves mitochondrial quality control during aging.Oxidative damage and mitochondrial decay in aging.Mitochondrial defects in neurodegenerative disease.Mitochondrial-nuclear epistasis: implications for human aging and longevity.Diseases caused by nuclear genes affecting mtDNA stability.Exercise attenuates the major hallmarks of aging.Comparison of mitochondrial mutation spectra in ageing human colonic epithelium and disease: absence of evidence for purifying selection in somatic mitochondrial DNA point mutations.Analysis of repeat-mediated deletions in the mitochondrial genome of Saccharomyces cerevisiaeThe somatic common deletion in mitochondrial DNA is decreased in schizophreniaThe reductive hotspot hypothesis of mammalian aging: membrane metabolism magnifies mutant mitochondrial mischief.
P2860
Q24635310-91A33934-F983-43C0-8867-D052C629B62EQ24676151-5F4B4E40-7FEA-49DF-99D6-2ED70344D231Q26746323-67C0AEA6-7969-4DFC-8EA4-D7A933203DD3Q26865053-D3C5FB97-3AA4-4FB4-8D76-6F53B9237004Q27000745-8BE2C674-327A-4499-8B74-20A629E2D83BQ27012566-48B5C263-0595-41B8-9641-47DA24E841C3Q27309281-BD73D3F5-AC2F-49C6-B315-3EEA895FC7BFQ28073272-9D0A84FA-76C7-425B-B389-74FF8DA0A085Q28394689-C22B3416-0B85-4DCB-B6AE-828B46F6CCBAQ28474793-A02F885A-1740-4310-BB1D-FD7EC6009C30Q29547303-9DF06358-6E31-46C9-89EC-04BE1B07C866Q30760899-BF16F08A-EC7E-41FE-8020-F2DBF56D99FAQ30834205-D846BF66-83F3-49C2-BB89-88841B8862BCQ33280200-E4C88462-D09B-4612-ABB5-DB6752BFC4E2Q33364885-AEA8BCF3-5468-46F3-A2B0-AF7A53EB713BQ33405486-00F2A355-346A-4315-B69F-990C1314627AQ33689022-B1C3989A-06C0-47D2-96E1-385EA528B793Q33711128-BE898DEF-9D26-424D-93CA-C82B6D5EE760Q33728309-1CE59D60-CC6C-445E-A83E-820DCC20760DQ33735571-B957E9D3-C975-4735-AA3E-C575A60711EDQ33796548-912520C0-27C2-4DF9-9E8B-48859EB7E0B7Q33821051-CF9A97E3-1AFF-4BD9-ACC9-65176DC8C2D6Q33826111-72C776EA-5A9A-41B9-ACA8-ADDD8B4FA959Q33859512-37DE4584-4796-4647-BF51-52F55E01FE0CQ33868432-DD35F4DC-E6D8-44B3-AE55-A78E8D1D1AE3Q33910255-DBC5AA3A-4368-479A-8FCA-C283C706FDF3Q34009983-63C7B9AF-B1E3-49A0-B551-B004CFE273DCQ34033991-F218231D-010D-4C05-A0AB-8E909C115003Q34145586-896DD4B7-ABA4-4E79-BF54-4A4B466444E7Q34311406-2D8533F3-1A41-4F1F-ABED-780C4C6135EBQ34325475-A4AE64A5-C02F-432B-A509-9F4D7049F86DQ34326443-E2926BA8-584A-4847-AB09-3EB8DF31E974Q34366678-503CCA8F-8B79-41DA-A284-08F0B7F58C81Q34367770-57A693CC-5121-4B37-ABF4-C085E565F5E7Q34386744-4A438AAB-1598-4018-AEEA-0524D7AA76B2Q34449998-19411E8B-B146-4BB7-96EB-31725F6C3E55Q34481936-1F7BAE4A-968D-41FD-87A7-C50D88BC79DAQ34586803-0E55DA05-F752-4638-B393-449CE0AA2193Q34613536-AE999E89-05DB-48AB-B8D0-FEDA419353D3Q34621576-F29FBB0A-6B17-4409-966E-122B72B2609A
P2860
Detection of a specific mitochondrial DNA deletion in tissues of older humans.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Detection of a specific mitochondrial DNA deletion in tissues of older humans.
@ast
Detection of a specific mitochondrial DNA deletion in tissues of older humans.
@en
type
label
Detection of a specific mitochondrial DNA deletion in tissues of older humans.
@ast
Detection of a specific mitochondrial DNA deletion in tissues of older humans.
@en
prefLabel
Detection of a specific mitochondrial DNA deletion in tissues of older humans.
@ast
Detection of a specific mitochondrial DNA deletion in tissues of older humans.
@en
P2860
P356
P1476
Detection of a specific mitochondrial DNA deletion in tissues of older humans.
@en
P2093
G A Cortopassi
P2860
P304
P356
10.1093/NAR/18.23.6927
P407
P577
1990-12-01T00:00:00Z