Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors. - Wikidata - wikimedia - TriplyDB

Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors.

Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors.

http://www.wikidata.org/entity/Q33699094

about

Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector Hedgehog Cholesterolysis: Specialized Gatekeeper to Oncogenic Signaling The mechanistic basis of arsenicosis: pathogenesis of skin cancer Genetic variations in the sonic hedgehog pathway affect clinical outcomes in non-muscle-invasive bladder cancer Clinicopathological correlates of Gli1 expression in a population-based cohort of patients with newly diagnosed bladder cancer MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways.Hedgehog pathway activation in human transitional cell carcinoma of the bladder Genes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen related receptor β GLI3 Links Environmental Arsenic Exposure and Human Fetal Growth.Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival.Arsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context-Dependent Manner.Association between In Utero arsenic exposure, placental gene expression, and infant birth weight: a US birth cohort study.Hedgehog signaling regulates bladder cancer growth and tumorigenicity Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity.The hedgehog processing pathway is required for NSCLC growth and survival Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma.Transcription Factor KLF5 Binds a Cyclin E1 Polymorphic Intronic Enhancer to Confer Increased Bladder Cancer Risk MTH1 expression is required for effective transformation by oncogenic HRAS.Direct binding of arsenic trioxide to AMPK and generation of inhibitory effects on acute myeloid leukemia precursors.Pyrvinium attenuates Hedgehog signaling downstream of smoothened.Inorganic arsenic can be potent granulotoxin in mammalian neutrophils in vitro.Urothelial Carcinoma Stem Cells: Current Concepts, Controversies, and Methods.

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Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors.

http://www.wikidata.org/entity/Q33699094

description

2010 nî lūn-bûn

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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2010 թվականի փետրվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Activation of Hedgehog signali ...... ogy of arsenic-induced tumors.

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Activation of Hedgehog signali ...... ogy of arsenic-induced tumors.

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Activation of Hedgehog signali ...... ogy of arsenic-induced tumors.

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Cancer Research

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P2860

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing

A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

Low-dose arsenic compromises the immune response to influenza A infection in vivo

Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

PTCH2, a novel human patched gene, undergoing alternative splicing and up-regulated in basal cell carcinomas

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation

Hedgehog signaling in animal development: paradigms and principles

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

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