Adamantyl-substituted retinoid-related molecules bind small heterodimer partner and modulate the Sin3A repressor. - Wikidata - wikimedia - TriplyDB

Adamantyl-substituted retinoid-related molecules bind small heterodimer partner and modulate the Sin3A repressor.

Adamantyl-substituted retinoid-related molecules bind small heterodimer partner and modulate the Sin3A repressor.

http://www.wikidata.org/entity/Q33707816

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Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis Lipid-sensors, enigmatic-orphan and orphan nuclear receptors as therapeutic targets in breast-cancer Insights into Orphan Nuclear Receptors as Prognostic Markers and Novel Therapeutic Targets for Breast Cancer Nuclear receptors and epigenetic regulation: opportunities for nutritional targeting and disease prevention Nuclear receptors in bone physiology and diseases Structural insights into gene repression by the orphan nuclear receptor SHP Role of nuclear receptor SHP in metabolism and cancer.Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells.Nuclear receptor SHP, a death receptor that targets mitochondria, induces apoptosis and inhibits tumor growth.Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis The lipophilic bullet hits the targets: medicinal chemistry of adamantane derivatives Upregulation of miR-150* and miR-630 induces apoptosis in pancreatic cancer cells by targeting IGF-1R.Characterization of the mitochondrial localization of the nuclear receptor SHP and regulation of its subcellular distribution by interaction with Bcl2 and HNF4α.Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes.Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partner The orphan nuclear receptor SHP is a positive regulator of osteoblastic bone formation.A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways.New Insights into Orphan Nuclear Receptor SHP in Liver Cancer Reversal by RARα agonist Am580 of c-Myc-induced imbalance in RARα/RARγ expression during MMTV-Myc tumorigenesis.Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development The role of FXR in disorders of bile acid homeostasis.FXR agonists enhance the sensitivity of biliary tract cancer cells to cisplatin via SHP dependent inhibition of Bcl-xL expression.Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis.Minireview: role of orphan nuclear receptors in cancer and potential as drug targets Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis.Epigenomic regulation of bile acid metabolism: emerging role of transcriptional cofactors.Nuclear receptor small heterodimer partner in apoptosis signaling and liver cancer.A Novel Small Molecule Activator of Nuclear Receptor SHP Inhibits HCC Cell Migration via Suppressing Ccl2.Nuclear receptor 4A (NR4A) family - orphans no more.NF-κB p65 recruited SHP regulates PDCD5-mediated apoptosis in cancer cells.Adamantyl arotinoids that inhibit IκB kinase α and IκB kinase β.Small heterodimer partner SHP mediates liver X receptor (LXR)-dependent suppression of inflammatory signaling by promoting LXR SUMOylation specifically in astrocytes.Adamantyl-substituted retinoid-related molecules induce apoptosis in human acute myelogenous leukemia cells.Maximal adamantyl-substituted retinoid-related molecule-induced apoptosis requires NF-κB noncanonical and canonical pathway activation SHP (small heterodimer partner) suppresses the transcriptional activity and nuclear localization of Hedgehog signalling protein Gli1.Highly twisted adamantyl arotinoids: synthesis, antiproliferative effects and RXR transactivation profiles.Catalyst-free multicomponent synthesis of novel adamantyl-containing tetrahydropyrimidine carboxylates.Adamantyl Retinoid-Related Molecules Induce Apoptosis in Pancreatic Cancer Cells by Inhibiting IGF-1R and Wnt/β-Catenin Pathways.An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferatio Insights into the binding mode and mechanism of action of some atypical retinoids as ligands of the small heterodimer partner (SHP).

P2860

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P2860

Adamantyl-substituted retinoid-related molecules bind small heterodimer partner and modulate the Sin3A repressor.

http://www.wikidata.org/entity/Q33707816

description

2007 nî lūn-bûn

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2007 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2007年の論文

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2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Adamantyl-substituted retinoid ...... modulate the Sin3A repressor.

@ast

Adamantyl-substituted retinoid ...... modulate the Sin3A repressor.

@en

type

label

Adamantyl-substituted retinoid ...... modulate the Sin3A repressor.

@ast

Adamantyl-substituted retinoid ...... modulate the Sin3A repressor.

@en

prefLabel

Adamantyl-substituted retinoid ...... modulate the Sin3A repressor.

@ast

Adamantyl-substituted retinoid ...... modulate the Sin3A repressor.

@en

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0008-5472.CAN-06-2164

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Cancer Research

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Adamantyl-substituted retinoid ...... d modulate the Sin3A repressor

@en

P2093

David D Moore

http://www.w3.org/2001/XMLSchema#string

Gang Liu

http://www.w3.org/2001/XMLSchema#string

Li Wang

http://www.w3.org/2001/XMLSchema#string

Lulu Farhana

http://www.w3.org/2001/XMLSchema#string

Marcia I Dawson

http://www.w3.org/2001/XMLSchema#string

Mark Leid

http://www.w3.org/2001/XMLSchema#string

Zeben Xia

http://www.w3.org/2001/XMLSchema#string

P2860

SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex

Use of chromatin immunoprecipitation to clone novel E2F target promoters

RNA interference is mediated by 21- and 22-nucleotide RNAs

Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation

Nucleotide binding states of hsp70 and hsp90 during sequential steps in the process of glucocorticoid receptor.hsp90 heterocomplex assembly

Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors

Cloning of the murine transcriptional corepressor component SAP18 and differential expression of its mRNA in the hematopoietic hierarchy

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis.

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318-325

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scholarly article

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10.1158/0008-5472.CAN-06-2164

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P433

1

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67

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P577

2007-01-01T00:00:00Z

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6590079

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17210713

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2833172

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