The molecular biology of cyclic nucleotide phosphodiesterases.
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Functional characterization of the human phosphodiesterase 7A1 promoterDeletion of phosphodiesterase 4D in mice shortens alpha(2)-adrenoceptor-mediated anesthesia, a behavioral correlate of emesisPer-Arnt-Sim domain-dependent association of cAMP-phosphodiesterase 8A1 with IkappaB proteinsRegulation of T-cell activation by phosphodiesterase 4B2 requires its dynamic redistribution during immunological synapse formationCloning and characterization of two splice variants of human phosphodiesterase 11ADelineation of RAID1, the RACK1 interaction domain located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5.Sildenafil citrate increases myocardial cGMP content in rat heart, decreases its hypertrophic response to isoproterenol and decreases myocardial leak of creatine kinase and troponin TClinical and preclinical treatment of urologic diseases with phosphodiesterase isoenzymes 5 inhibitors: an updateTargeting protein-protein interactions in complexes organized by A kinase anchoring proteinsIdentification and characterization of DdPDE3, a cGMP-selective phosphodiesterase from Dictyosteliumbeta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to GiImpaired growth and fertility of cAMP-specific phosphodiesterase PDE4D-deficient miceMiR-150 impairs inflammatory cytokine production by targeting ARRB-2 after blocking CD28/B7 costimulatory pathway.Induction of the cyclic nucleotide phosphodiesterase PDE4B is essential for LPS-activated TNF-alpha responsesCytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle.PDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblastsABCD of the phosphodiesterase family: interaction and differential activity in COPDCharacterization of a catalytic ligand bridging metal ions in phosphodiesterases 4 and 5 by molecular dynamics simulations and hybrid quantum mechanical/molecular mechanical calculations.PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalizationLong PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1)Remodelling of the PDE4 cAMP phosphodiesterase isoform profile upon monocyte-macrophage differentiation of human U937 cells.Role of PDE4 in superoxide anion generation through p44/42MAPK regulation: a cAMP and a PKA-independent mechanism.Cyclic phosphatidic acid stimulates cAMP production and inhibits growth in human colon cancer cells.The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastomaPhosphodiesterase 3/4 inhibitor zardaverine exhibits potent and selective antitumor activity against hepatocellular carcinoma both in vitro and in vivo independently of phosphodiesterase inhibition.The role of phosphodiesterase inhibitors in the management of pulmonary vascular diseasesPhosphodiesterase (PDE) inhibitors in the treatment of lower urinary tract dysfunction.Absence of muscarinic cholinergic airway responses in mice deficient in the cyclic nucleotide phosphodiesterase PDE4DPharmacologic agents elevating cAMP prevent arginase II expression and proliferation of pulmonary artery smooth muscle cells.Validation of PDE9A Gene Identified in GWAS Showing Strong Association with Milk Production Traits in Chinese Holstein.The G protein Gαs acts as a tumor suppressor in sonic hedgehog signaling-driven tumorigenesis.Treating COPD with PDE 4 inhibitors.The cyclic AMP phenotype of fragile X and autismCompartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory.Reduced adiposity and high-fat diet-induced adipose inflammation in mice deficient for phosphodiesterase 4B.Structure-Based Design of Novel Tetrahydro-Beta-Carboline Derivatives with a Hydrophilic Side Chain as Potential Phosphodiesterase Inhibitors.cAMP and mitochondria.Cyclic AMP compartments and signaling specificity: role of cyclic nucleotide phosphodiesterases.Sildenafil Can Affect Innate and Adaptive Immune System in Both Experimental Animals and Patients.Phosphodiesterase type 4D gene polymorphism: association with the response to short-acting bronchodilators in paediatric asthma patients.
P2860
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P2860
The molecular biology of cyclic nucleotide phosphodiesterases.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The molecular biology of cyclic nucleotide phosphodiesterases.
@ast
The molecular biology of cyclic nucleotide phosphodiesterases.
@en
type
label
The molecular biology of cyclic nucleotide phosphodiesterases.
@ast
The molecular biology of cyclic nucleotide phosphodiesterases.
@en
prefLabel
The molecular biology of cyclic nucleotide phosphodiesterases.
@ast
The molecular biology of cyclic nucleotide phosphodiesterases.
@en
P1476
The molecular biology of cyclic nucleotide phosphodiesterases
@en
P577
1999-01-01T00:00:00Z