The role of lysosomes in limiting drug toxicity in mice.
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Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenesChemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitorsIdentification of hepatic phospholipidosis inducers in sandwich-cultured rat hepatocytes, a physiologically relevant model, reveals altered basolateral uptake and biliary excretion of anionic probe substratesIntracellular Distribution-based Anticancer Drug Targeting: Exploiting a Lysosomal Acidification Defect Associated with Cancer Cells.A physiologically based pharmacokinetic model of alvespimycin in mice and extrapolation to rats and humans.Lysosomal trapping of a radiolabeled substrate of P-glycoprotein as a mechanism for signal amplification in PETSequestration of AS-DACA into acidic compartments of the membrane trafficking system as a mechanism of drug resistance in rhabdomyosarcomaThe contribution of lysosomotropism to autophagy perturbation.Cationic amphiphilic drugs cause a marked expansion of apparent lysosomal volume: implications for an intracellular distribution-based drug interaction.A mechanism for overcoming P-glycoprotein-mediated drug resistance: novel combination therapy that releases stored doxorubicin from lysosomes via lysosomal permeabilization using Dp44mT or DpC.Drug-drug interactions involving lysosomes: mechanisms and potential clinical implications.The in vitro biocompatibility and macrophage phagocytosis of Mg17Al12 phase in Mg-Al-Zn alloys.Inducible nitric oxide synthase in innate immune cells is important for restricting cyst formation of Toxoplasma gondii in the brain but not required for the protective immune process to remove the cysts.
P2860
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P2860
The role of lysosomes in limiting drug toxicity in mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The role of lysosomes in limiting drug toxicity in mice.
@ast
The role of lysosomes in limiting drug toxicity in mice.
@en
type
label
The role of lysosomes in limiting drug toxicity in mice.
@ast
The role of lysosomes in limiting drug toxicity in mice.
@en
prefLabel
The role of lysosomes in limiting drug toxicity in mice.
@ast
The role of lysosomes in limiting drug toxicity in mice.
@en
P2860
P356
P1476
The role of lysosomes in limiting drug toxicity in mice
@en
P2093
Jeffrey P Krise
Rosemary A Ndolo
P2860
P304
P356
10.1124/JPET.109.160226
P407
P577
2010-01-07T00:00:00Z