Effector CD4 cell tolerization is mediated through functional inactivation and involves preferential impairment of TNF-alpha and IFN-gamma expression potentials.
about
In vivo cyclophosphamide and IL-2 treatment impedes self-antigen-induced effector CD4 cell tolerization: implications for adoptive immunotherapy.Steady state dendritic cells present parenchymal self-antigen and contribute to, but are not essential for, tolerization of naive and Th1 effector CD4 cells.Dendritic cells program non-immunogenic prostate-specific T cell responses beginning at early stages of prostate tumorigenesis.Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen.T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression.Glycoprotein 96 can chaperone both MHC class I- and class II-restricted epitopes for in vivo presentation, but selectively primes CD8+ T cell effector function.Histone acetylation at the Ifng promoter in tolerized CD4 cells is associated with increased IFN-gamma expression during subsequent immunization to the same antigenPeripheral Tolerization of Effector and Memory T Cells: Implications for Autoimmunity and Tumor-Immunity.The E3 ubiquitin ligase Cbl-b regulates expansion but not functional activity of self-reactive CD4 T cellsReciprocal changes in tumor antigenicity and antigen-specific T cell function during tumor progressionAntibodies generated against conserved antigens expressed by bacteria and allergen-bearing fungi suppress airway disease.Tolerization of an established alphaB-crystallin-reactive T-cell response by intravenous antigen.
P2860
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P2860
Effector CD4 cell tolerization is mediated through functional inactivation and involves preferential impairment of TNF-alpha and IFN-gamma expression potentials.
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Effector CD4 cell tolerization ...... N-gamma expression potentials.
@ast
Effector CD4 cell tolerization ...... N-gamma expression potentials.
@en
type
label
Effector CD4 cell tolerization ...... N-gamma expression potentials.
@ast
Effector CD4 cell tolerization ...... N-gamma expression potentials.
@en
prefLabel
Effector CD4 cell tolerization ...... N-gamma expression potentials.
@ast
Effector CD4 cell tolerization ...... N-gamma expression potentials.
@en
P2093
P2860
P1433
P1476
Effector CD4 cell tolerization ...... N-gamma expression potentials.
@en
P2093
Adam J Adler
Amy D Higgins
Marianne A Mihalyo
Meixiao Long
P2860
P304
P356
10.1016/J.CELLIMM.2003.08.008
P577
2003-08-01T00:00:00Z