T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression.
about
NF-kappaB-regulated suppression of T-bet in T cells represses Th1 immune responses in pregnancy.Self-antigen prevents CD8 T cell effector differentiation by CD134 and CD137 dual costimulation.Histone acetylation at the Ifng promoter in tolerized CD4 cells is associated with increased IFN-gamma expression during subsequent immunization to the same antigenThe E3 ubiquitin ligase Cbl-b regulates expansion but not functional activity of self-reactive CD4 T cellsInflammation programs self-reactive CD8+ T cells to acquire T-box-mediated effector function but does not prevent deletional toleranceCD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells to program cytotoxic Th1 differentiation.Transcriptional regulatory networks for CD4 T cell differentiation.In vitro and in vivo differentiated effector CD8 T cells display divergent histone acetylation patterns within the Ifng locusPhenotypic and transcriptional profile correlates with functional plasticity of antigen-specific CD4+ T cells.
P2860
Q33281042-99D8EEF3-9F7F-4683-8F49-0E78DB88A95BQ33756678-9B6776E8-B691-4087-8BC8-45685E17BB4DQ33791226-9A429B81-8268-443A-92A7-8852CA042C34Q33802637-819D2F19-F8D8-4B9B-AED6-DA7C429DC5D6Q34066709-6BBD6F66-117E-46A0-A839-A141E09C3D45Q35228053-E0EB3B8F-5A95-4181-917A-00D82D903202Q36015482-695C5FD0-9F91-4ADB-9220-70A1D3117F30Q37194984-F9C685DA-739C-4FCB-A0F4-2450C6C15E69Q42238387-29115245-0CE3-4044-9E83-DC454A1242C3
P2860
T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression.
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2006 nî lūn-bûn
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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2006 թվականի հունվարին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
T-bet down-modulation in toler ...... impairs IFN-gamma expression.
@ast
T-bet down-modulation in toler ...... impairs IFN-gamma expression.
@en
type
label
T-bet down-modulation in toler ...... impairs IFN-gamma expression.
@ast
T-bet down-modulation in toler ...... impairs IFN-gamma expression.
@en
prefLabel
T-bet down-modulation in toler ...... impairs IFN-gamma expression.
@ast
T-bet down-modulation in toler ...... impairs IFN-gamma expression.
@en
P2093
P2860
P1476
T-bet down-modulation in toler ...... impairs IFN-gamma expression.
@en
P2093
Aaron M Slaiby
Adam J Adler
Adam T Hagymasi
Alexander C Lichtler
Marianne A Mihalyo
Meixiao Long
Steven L Reiner
P2860
P304
P356
10.4049/JIMMUNOL.176.2.1036
P407
P577
2006-01-01T00:00:00Z