Inhibition of lysosomal degradation rescues pentamidine-mediated decreases of K(IR)2.1 ion channel expression but not that of K(v)11.1.

Inhibition of lysosomal degradation rescues pentamidine-mediated decreases of K(IR)2.1 ion channel expression but not that of K(v)11.1.

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http://www.wikidata.org/entity/Q33757989
Over-expression of microRNA-1 causes arrhythmia by disturbing intracellular trafficking system.Expression of three topologically distinct membrane proteins elicits unique stress response pathways in the yeast Saccharomyces cerevisiaeESCRT regulates surface expression of the Kir2.1 potassium channel.Structure-activity relationships of pentamidine-affected ion channel trafficking and dofetilide mediated rescue.PA-6 inhibits inward rectifier currents carried by V93I and D172N gain-of-function KIR2.1 channels, but increases channel protein expression.Inhibiting the clathrin-mediated endocytosis pathway rescues K(IR)2.1 downregulation by pentamidine.Class III antiarrhythmic drugs amiodarone and dronedarone impair KIR 2.1 backward trafficking.Efficient and specific cardiac IK₁ inhibition by a new pentamidine analogue.Cardiac Arrhythmias and Antiarrhythmic Drugs: An Autophagic Perspective.
P2860

Inhibition of lysosomal degradation rescues pentamidine-mediated decreases of K(IR)2.1 ion channel expression but not that of K(v)11.1.

Item
http://www.wikidata.org/entity/Q33757989
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2010 nî lūn-bûn
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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Inhibition of lysosomal degrad ...... sion but not that of K(v)11.1.
@ast
Inhibition of lysosomal degrad ...... sion but not that of K(v)11.1.
@en
type
label
Inhibition of lysosomal degrad ...... sion but not that of K(v)11.1.
@ast
Inhibition of lysosomal degrad ...... sion but not that of K(v)11.1.
@en
prefLabel
Inhibition of lysosomal degrad ...... sion but not that of K(v)11.1.
@ast
Inhibition of lysosomal degrad ...... sion but not that of K(v)11.1.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Inhibition of lysosomal degrad ...... sion but not that of K(v)11.1.
@en
P2093
P304
P31
P356
10.1016/J.EJPHAR.2010.10.093
P407
P433
P478
P577
P698