Chicken retinas contain a retinoid isomerase activity that catalyzes the direct conversion of all-trans-retinol to 11-cis-retinol
about
How vision begins: an odysseyRecent advances in the dark adaptation investigationsRPE65 is present in human green/red cones and promotes photopigment regeneration in an in vitro cone cell modelMembrane-binding and enzymatic properties of RPE65Chemistry of the retinoid (visual) cycleHuman cone photoreceptor dependence on RPE65 isomeraseIdentification of the 11-cis-specific retinyl-ester synthase in retinal Müller cells as multifunctional O-acyltransferase (MFAT).The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision.The retinal pigment epithelium in health and diseaseRetinoid processing in cone and Müller cell linesSelf-complementary AAV-mediated gene therapy restores cone function and prevents cone degeneration in two models of Rpe65 deficiency.Differential role for synaptojanin 1 in rod and cone photoreceptors.The role of 11-cis-retinyl esters in vertebrate cone vision.Histopathology and functional correlations in a patient with a mutation in RPE65, the gene for retinol isomerase.Interphotoreceptor retinoid-binding protein as the physiologically relevant carrier of 11-cis-retinol in the cone visual cycle.Diacylglycerol O-acyltransferase type-1 synthesizes retinyl esters in the retina and retinal pigment epitheliumNrl-knockout mice deficient in Rpe65 fail to synthesize 11-cis retinal and cone outer segments.Targeted transgene expression in muller glia of normal and diseased retinas using lentiviral vectors.An alternative isomerohydrolase in the retinal Müller cells of a cone-dominant species.Structure of zebrafish IRBP reveals fatty acid bindingIdentification of DES1 as a vitamin A isomerase in Müller glial cells of the retina.Physiological significance and expression of P450s in the developing eye.RPE65 from cone-dominant chicken is a more efficient isomerohydrolase compared with that from rod-dominant species.Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agentsEvidence for RPE65-independent vision in the cone-dominated zebrafish retina.A novel cone visual cycle in the cone-dominated retina.Trafficking of membrane-associated proteins to cone photoreceptor outer segments requires the chromophore 11-cis-retinalRpe65-/- and Lrat-/- mice: comparable models of leber congenital amaurosis.The role of interphotoreceptor retinoid-binding protein on the translocation of visual retinoids and function of cone photoreceptorsLoss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate.Formation of all-trans retinol after visual pigment bleaching in mouse photoreceptorsEvolution and the origin of the visual retinoid cycle in vertebrates.Retinal light damage: mechanisms and protection.Retinol dehydrogenases (RDHs) in the visual cycle.The cone-specific visual cycle.Retinol dehydrogenase 8 and ATP-binding cassette transporter 4 modulate dark adaptation of M-cones in mammalian retina.Allosteric modulation of the substrate specificity of acyl-CoA wax alcohol acyltransferase 2.iPSC-Derived Retina Transplants Improve Vision in rd1 End-Stage Retinal-Degeneration MiceNormal cone function requires the interphotoreceptor retinoid binding protein.Retinol-binding site in interphotoreceptor retinoid-binding protein (IRBP): a novel hydrophobic cavity.
P2860
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P2860
Chicken retinas contain a retinoid isomerase activity that catalyzes the direct conversion of all-trans-retinol to 11-cis-retinol
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol
@ast
Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol
@en
type
label
Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol
@ast
Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol
@en
prefLabel
Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol
@ast
Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol
@en
P2093
P2860
P356
P1433
P1476
Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol
@en
P2093
Alberto Ruiz
Gabriel H Travis
Nathan L Mata
Roxana A Radu
P2860
P304
11715-11721
P356
10.1021/BI050942M
P407
P577
2005-09-01T00:00:00Z