Chicken retinas contain a retinoid isomerase activity that catalyzes the direct conversion of all-trans-retinol to 11-cis-retinol - Wikidata - wikimedia - TriplyDB

Chicken retinas contain a retinoid isomerase activity that catalyzes the direct conversion of all-trans-retinol to 11-cis-retinol

Chicken retinas contain a retinoid isomerase activity that catalyzes the direct conversion of all-trans-retinol to 11-cis-retinol

http://www.wikidata.org/entity/Q33777121

about

How vision begins: an odyssey Recent advances in the dark adaptation investigations RPE65 is present in human green/red cones and promotes photopigment regeneration in an in vitro cone cell model Membrane-binding and enzymatic properties of RPE65 Chemistry of the retinoid (visual) cycle Human cone photoreceptor dependence on RPE65 isomerase Identification of the 11-cis-specific retinyl-ester synthase in retinal Müller cells as multifunctional O-acyltransferase (MFAT).The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision.The retinal pigment epithelium in health and disease Retinoid processing in cone and Müller cell lines Self-complementary AAV-mediated gene therapy restores cone function and prevents cone degeneration in two models of Rpe65 deficiency.Differential role for synaptojanin 1 in rod and cone photoreceptors.The role of 11-cis-retinyl esters in vertebrate cone vision.Histopathology and functional correlations in a patient with a mutation in RPE65, the gene for retinol isomerase.Interphotoreceptor retinoid-binding protein as the physiologically relevant carrier of 11-cis-retinol in the cone visual cycle.Diacylglycerol O-acyltransferase type-1 synthesizes retinyl esters in the retina and retinal pigment epithelium Nrl-knockout mice deficient in Rpe65 fail to synthesize 11-cis retinal and cone outer segments.Targeted transgene expression in muller glia of normal and diseased retinas using lentiviral vectors.An alternative isomerohydrolase in the retinal Müller cells of a cone-dominant species.Structure of zebrafish IRBP reveals fatty acid binding Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina.Physiological significance and expression of P450s in the developing eye.RPE65 from cone-dominant chicken is a more efficient isomerohydrolase compared with that from rod-dominant species.Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents Evidence for RPE65-independent vision in the cone-dominated zebrafish retina.A novel cone visual cycle in the cone-dominated retina.Trafficking of membrane-associated proteins to cone photoreceptor outer segments requires the chromophore 11-cis-retinal Rpe65-/- and Lrat-/- mice: comparable models of leber congenital amaurosis.The role of interphotoreceptor retinoid-binding protein on the translocation of visual retinoids and function of cone photoreceptors Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate.Formation of all-trans retinol after visual pigment bleaching in mouse photoreceptors Evolution and the origin of the visual retinoid cycle in vertebrates.Retinal light damage: mechanisms and protection.Retinol dehydrogenases (RDHs) in the visual cycle.The cone-specific visual cycle.Retinol dehydrogenase 8 and ATP-binding cassette transporter 4 modulate dark adaptation of M-cones in mammalian retina.Allosteric modulation of the substrate specificity of acyl-CoA wax alcohol acyltransferase 2.iPSC-Derived Retina Transplants Improve Vision in rd1 End-Stage Retinal-Degeneration Mice Normal cone function requires the interphotoreceptor retinoid binding protein.Retinol-binding site in interphotoreceptor retinoid-binding protein (IRBP): a novel hydrophobic cavity.

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Chicken retinas contain a retinoid isomerase activity that catalyzes the direct conversion of all-trans-retinol to 11-cis-retinol

http://www.wikidata.org/entity/Q33777121

description

2005 nî lūn-bûn

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2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol

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Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol

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type

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Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol

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Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol

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Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol

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Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol

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Chicken retinas contain a reti ...... rans-retinol to 11-cis-retinol

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P2093

Alberto Ruiz

http://www.w3.org/2001/XMLSchema#string

Gabriel H Travis

http://www.w3.org/2001/XMLSchema#string

Nathan L Mata

http://www.w3.org/2001/XMLSchema#string

Roxana A Radu

http://www.w3.org/2001/XMLSchema#string

Tam V Bui

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular and biochemical characterization of lecithin retinol acyltransferase

Rpe65 is a retinyl ester binding protein that presents insoluble substrate to the isomerase in retinal pigment epithelial cells

Differential interaction of lecithin-retinol acyltransferase with cellular retinol binding proteins

Isomerization and oxidation of vitamin a in cone-dominant retinas: a novel pathway for visual-pigment regeneration in daylight

Evidence for a lecithin-retinol acyltransferase activity in the rat small intestine.

Retinol esterification by rat liver microsomes. Evidence for a fatty acyl coenzyme A: retinol acyltransferase.

Retinoid requirements for recovery of sensitivity after visual-pigment bleaching in isolated photoreceptors.

Distribution of 11-cis LRAT, 11-cis RD and 11-cis REH in bovine retinal pigment epithelium membranes.

G proteins and phototransduction.

Lecithin:retinol acyltransferase in retinal pigment epithelial microsomes.

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scholarly article

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10.1021/BI050942M

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35

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44

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7631492

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16128572

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all-trans-retinal

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2851629

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