The role of interphotoreceptor retinoid-binding protein on the translocation of visual retinoids and function of cone photoreceptors
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Secretory defect and cytotoxicity: the potential disease mechanisms for the retinitis pigmentosa (RP)-associated interphotoreceptor retinoid-binding protein (IRBP)Recent advances in the dark adaptation investigationsRod and cone visual pigments and phototransduction through pharmacological, genetic, and physiological approachesRetinoid content, visual responses, and ocular morphology are compromised in the retinas of mice lacking the retinol-binding protein receptor, STRA6Independent losses of visual perception genes Gja10 and Rbp3 in echolocating bats (Order: Chiroptera)Pharmacological Amelioration of Cone Survival and Vision in a Mouse Model for Leber Congenital AmaurosisGene therapy regenerates protein expression in cone photoreceptors in Rpe65(R91W/R91W) mice.Bax-induced apoptosis in Leber's congenital amaurosis: a dual role in rod and cone degeneration.A homozygous missense mutation in the IRBP gene (RBP3) associated with autosomal recessive retinitis pigmentosa.Rescue of enzymatic function for disease-associated RPE65 proteins containing various missense mutations in non-active sites.Exaggerated eye growth in IRBP-deficient mice in early developmentCone outer segment extracellular matrix as binding domain for interphotoreceptor retinoid-binding protein.Chromophore supply rate-limits mammalian photoreceptor dark adaptation.Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase.The mammalian cone visual cycle promotes rapid M/L-cone pigment regeneration independently of the interphotoreceptor retinoid-binding protein.Receptor interacting protein kinase-mediated necrosis contributes to cone and rod photoreceptor degeneration in the retina lacking interphotoreceptor retinoid-binding proteinCRALBP supports the mammalian retinal visual cycle and cone vision.Interphotoreceptor retinoid-binding protein protects retinoids from photodegradationInterphotoreceptor retinoid-binding protein as the physiologically relevant carrier of 11-cis-retinol in the cone visual cycle.Diacylglycerol O-acyltransferase type-1 synthesizes retinyl esters in the retina and retinal pigment epitheliumAn S-opsin knock-in mouse (F81Y) reveals a role for the native ligand 11-cis-retinal in cone opsin biosynthesisStructure of zebrafish IRBP reveals fatty acid bindingBiocompatibility of a Synthetic Biopolymer for the Treatment of Rhegmatogenous Retinal Detachment.Vitamin A activates rhodopsin and sensitizes it to ultraviolet light.Interphotoreceptor Retinoid-Binding Protein Mitigates Cellular Oxidative Stress and Mitochondrial Dysfunction Induced by All-trans-Retinal.Vitamin A derivatives as treatment options for retinal degenerative diseases.New insights into retinoid metabolism and cycling within the retinaNeuronal programmed cell death-1 ligand expression regulates retinal ganglion cell number in neonatal and adult mice.CNTF-mediated protection of photoreceptors requires initial activation of the cytokine receptor gp130 in Müller glial cells.IRBP deficiency permits precocious ocular development and myopia.Analysis of gene expression in wild-type and Notch1 mutant retinal cells by single cell profiling.Targeted Multifunctional Lipid ECO Plasmid DNA Nanoparticles as Efficient Non-viral Gene Therapy for Leber's Congenital AmaurosisThe cone-specific visual cycle.Functional Rescue of Retinal Degeneration-Associated Mutant RPE65 Proteins.Retinol dehydrogenase 8 and ATP-binding cassette transporter 4 modulate dark adaptation of M-cones in mammalian retina.The PI3K-PTEN tug-of-war, oxidative stress and retinal degeneration.Retinol-binding site in interphotoreceptor retinoid-binding protein (IRBP): a novel hydrophobic cavity.Interphotoreceptor retinoid binding protein; myths and mysteries.Evidence for two retinoid cycles in the cone-dominated chicken eyeScreening genes of the visual cycle RGR, RBP1 and RBP3 identifies rare sequence variations.
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The role of interphotoreceptor retinoid-binding protein on the translocation of visual retinoids and function of cone photoreceptors
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on February 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
The role of interphotoreceptor ...... unction of cone photoreceptors
@en
The role of interphotoreceptor ...... nction of cone photoreceptors.
@nl
type
label
The role of interphotoreceptor ...... unction of cone photoreceptors
@en
The role of interphotoreceptor ...... nction of cone photoreceptors.
@nl
prefLabel
The role of interphotoreceptor ...... unction of cone photoreceptors
@en
The role of interphotoreceptor ...... nction of cone photoreceptors.
@nl
P2093
P2860
P1476
The role of interphotoreceptor ...... unction of cone photoreceptors
@en
P2093
Gabriel H Travis
Marcia Lloyd
Minghao Jin
Roxana A Radu
Songhua Li
Steven Nusinowitz
P2860
P304
P356
10.1523/JNEUROSCI.3882-08.2009
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P577
2009-02-01T00:00:00Z