about
SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreadingTumor Suppressor Inactivation in the Pathogenesis of Adult T-Cell LeukemiaCrkL is recruited through its SH2 domain to the erythropoietin receptor and plays a role in Lyn-mediated receptor signalingInpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsivenessLyn, PKC-delta, SHIP-1 interactions regulate GPVI-mediated platelet-dense granule secretionDifferential roles for the inositol phosphatase SHIP in the regulation of macrophages and lymphocytes.Phosphoinositide 3-kinase inhibition in cancer treatment.Discovery and development of small molecule SHIP phosphatase modulators.The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradationSynthesis and initial evaluation of quinoline-based inhibitors of the SH2-containing inositol 5'-phosphatase (SHIP).Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis.The chemical biology of phosphoinositide 3-kinases.A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.Activation/Inhibition of mast cells by supra-optimal antigen concentrationsActivation of SHIP by NADPH oxidase-stimulated Lyn leads to enhanced apoptosis in neutrophils.Activin/TGF-beta induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIP.The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression.Compound heterozygosity for Pten and SHIP augments T-dependent humoral immune responses and cytokine production by CD(4+) T cells.AQX-1125, small molecule SHIP1 activator inhibits bleomycin-induced pulmonary fibrosis.
P2860
Q24290742-2C086A75-2D20-445E-8A1A-D4D9348819D3Q28081287-085302D4-D2D4-49FC-BDDF-6A713FACBB8AQ28205275-60AC1F71-20B1-4E9B-B277-472128408B26Q28590549-EFA3131E-D370-49BB-A0C7-5838120B0738Q33479912-49C89109-87A6-459E-9D90-C978F4BB5786Q33596651-4C7D34FC-A4CE-4834-B708-E13346B9EDCDQ34481485-4ABA4CA0-779F-4DC9-A5E7-F12DB6741283Q35058356-6C6A3A7A-3B58-4678-A892-B791A1F86922Q35814123-81AF53C1-BA9F-4926-9B33-977F3290BA56Q36236827-BFF0F4E5-6ABF-4752-8A18-F2BC650066ACQ36402414-74E795AE-8165-4D7A-B1B6-C68853D3F73FQ38042382-0380CF15-3506-4A33-B792-905C3E198C25Q40562808-FE770D40-2D93-4205-8626-27FC7BDFC9C4Q41094713-063DC710-5BED-4CA3-88A1-38CF1C56AC30Q43810192-44C1C61F-EDFE-4AE0-A66D-32F44C7A16EDQ44226377-1C8E86B1-12E0-4BA9-AFD9-AFDF46C58F51Q44557868-DB3B10A2-19F2-4273-AC82-FAE2F3E97A2DQ44935591-B0527EA9-7380-4C68-B1E3-B5297AF4ED2CQ48208455-99FA4A2E-3F00-4929-8A5F-D859101961B0
P2860
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
SHIPs ahoy.
@ast
SHIPs ahoy.
@en
type
label
SHIPs ahoy.
@ast
SHIPs ahoy.
@en
prefLabel
SHIPs ahoy.
@ast
SHIPs ahoy.
@en
P2093
P1476
SHIPs ahoy.
@en
P2093
C D Helgason
J Kalesnikoff
M R Hughes
R K Humphries
P304
P356
10.1016/S1357-2725(99)00072-2
P577
1999-10-01T00:00:00Z