CrkL is recruited through its SH2 domain to the erythropoietin receptor and plays a role in Lyn-mediated receptor signaling

CrkL is recruited through its SH2 domain to the erythropoietin receptor and plays a role in Lyn-mediated receptor signaling

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http://www.wikidata.org/entity/Q28205275
Q28161634
sameAs
Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activityIn vivo targeting of the growth hormone receptor (GHR) Box1 sequence demonstrates that the GHR does not signal exclusively through JAK2.Advances in understanding the pathogenesis of primary familial and congenital polycythaemiaProliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera.Peginesatide and erythropoietin stimulate similar erythropoietin receptor-mediated signal transduction and gene induction events.Integrating novel signaling pathways involved in erythropoiesis.Three Tyrosine Residues in the Erythropoietin Receptor Are Essential for Janus Kinase 2 V617F Mutant-induced Tumorigenesis.CRKL promotes lung cancer cell invasion through ERK-MMP9 pathway.Lyn deficiency reduces GATA-1, EKLF and STAT5, and induces extramedullary stress erythropoiesis.Core erythropoietin receptor signals for late erythroblast development.Rac is activated by erythropoietin or interleukin-3 and is involved in activation of the Erk signaling pathway.Csk-binding protein mediates sequential enzymatic down-regulation and degradation of Lyn in erythropoietin-stimulated cells.A new point mutation in EPOR inducing a short deletion in congenital erythrocytosis.EPO:p-EPOR:p-JAK2:LYN:IRS2 binds CRKL:RAPGEF1LYN phosphorylates CRKL in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1Erythropoietin activates RAS
P2860

CrkL is recruited through its SH2 domain to the erythropoietin receptor and plays a role in Lyn-mediated receptor signaling

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http://www.wikidata.org/entity/Q28205275
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2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
CrkL is recruited through its ...... yn-mediated receptor signaling
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CrkL is recruited through its ...... yn-mediated receptor signaling
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CrkL is recruited through its ...... yn-mediated receptor signaling
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CrkL is recruited through its ...... yn-mediated receptor signaling
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CrkL is recruited through its ...... yn-mediated receptor signaling
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CrkL is recruited through its ...... yn-mediated receptor signaling
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CrkL is recruited through its ...... yn-mediated receptor signaling
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CrkL is recruited through its ...... yn-mediated receptor signaling
@en
CrkL is recruited through its ...... yn-mediated receptor signaling
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P1433
P1476
P2093
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CrkL is recruited through its ...... yn-mediated receptor signaling
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P304
P31
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P433
P478
P577
P698
P921