Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma
about
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65A secreted tyrosine kinase acts in the extracellular environmentInhibitory effect of SPE-39 due to tyrosine phosphorylation and ubiquitination on the function of Vps33B in the EGF-stimulated cellsDiscoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signalingPhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouseClinical use of crizotinib for the treatment of non-small cell lung cancerFunctional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling)Discoidin Domain Receptors: Potential Actors and Targets in CancerThe landscape of targeted therapies for cholangiocarcinoma: current status and emerging targetsGenetic profiling of intrahepatic cholangiocarcinoma and its clinical implication in targeted therapyOncogenic kinase fusions: an evolving arena with innovative clinical opportunitiesALK and ROS1 as targeted therapy paradigms and clinical implications to overcome crizotinib resistanceExpanding the ubiquitin code through post-translational modificationALK and ROS1 as a joint target for the treatment of lung cancer: a reviewThe minority report: targeting the rare oncogenes in NSCLCRegulation of cardiac proteasomes by ubiquitination, SUMOylation, and beyondLY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft modelsROS1 rearrangements define a unique molecular class of lung cancers.ROS1 and ALK fusions in colorectal cancer, with evidence of intratumoral heterogeneity for molecular drivers.Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinomaCrizotinib in ROS1-rearranged non-small-cell lung cancer.PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutationsSystems Proteomics View of the Endogenous Human Claudin Protein FamilyPhosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutantsBreakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer typesPINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activityFluorescence in situ hybridization in surgical pathology: principles and applications.Therapeutic options for intrahepatic cholangiocarcinoma14-3-3ε boosts bleomycin-induced DNA damage response by inhibiting the drug-resistant activity of MVPKinase fusions are frequent in Spitz tumours and spitzoid melanomas.Regulators of Cholangiocyte Proliferation.TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity.Biomarkers That Currently Affect Clinical Practice in Lung Cancer: EGFR, ALK, MET, ROS-1, and KRASChromosome 3 anomalies investigated by genome wide SNP analysis of benign, low malignant potential and low grade ovarian serous tumours.Identifying and targeting ROS1 gene fusions in non-small cell lung cancer.Current concepts on the molecular pathology of non-small cell lung carcinoma.Molecular pathways: ROS1 fusion proteins in cancer.Specific visualization and identification of phosphoproteome in gels.Mouse model for ROS1-rearranged lung cancerMissense variants of uncertain significance (VUS) altering the phosphorylation patterns of BRCA1 and BRCA2.
P2860
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P2860
Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma
@ast
Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma
@en
type
label
Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma
@ast
Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma
@en
prefLabel
Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma
@ast
Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma
@en
P2093
P2860
P1433
P1476
Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma
@en
P2093
Baiyong Shen
Brett Norris
Chenghong Peng
Chunlin Wu
Cynthia Reeves
Feizhou Huang
Gregory Innocenti
Herbert Haack
Hongwei Li
P2860
P304
P356
10.1371/JOURNAL.PONE.0015640
P407
P577
2011-01-06T00:00:00Z