Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma - Wikidata - wikimedia - TriplyDB

Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma

Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma

http://www.wikidata.org/entity/Q33799157

about

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65 A secreted tyrosine kinase acts in the extracellular environment Inhibitory effect of SPE-39 due to tyrosine phosphorylation and ubiquitination on the function of Vps33B in the EGF-stimulated cells Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse Clinical use of crizotinib for the treatment of non-small cell lung cancer Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling)Discoidin Domain Receptors: Potential Actors and Targets in Cancer The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets Genetic profiling of intrahepatic cholangiocarcinoma and its clinical implication in targeted therapy Oncogenic kinase fusions: an evolving arena with innovative clinical opportunities ALK and ROS1 as targeted therapy paradigms and clinical implications to overcome crizotinib resistance Expanding the ubiquitin code through post-translational modification ALK and ROS1 as a joint target for the treatment of lung cancer: a review The minority report: targeting the rare oncogenes in NSCLC Regulation of cardiac proteasomes by ubiquitination, SUMOylation, and beyond LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models ROS1 rearrangements define a unique molecular class of lung cancers.ROS1 and ALK fusions in colorectal cancer, with evidence of intratumoral heterogeneity for molecular drivers.Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma Crizotinib in ROS1-rearranged non-small-cell lung cancer.PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations Systems Proteomics View of the Endogenous Human Claudin Protein Family Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity Fluorescence in situ hybridization in surgical pathology: principles and applications.Therapeutic options for intrahepatic cholangiocarcinoma 14-3-3ε boosts bleomycin-induced DNA damage response by inhibiting the drug-resistant activity of MVP Kinase fusions are frequent in Spitz tumours and spitzoid melanomas.Regulators of Cholangiocyte Proliferation.TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity.Biomarkers That Currently Affect Clinical Practice in Lung Cancer: EGFR, ALK, MET, ROS-1, and KRAS Chromosome 3 anomalies investigated by genome wide SNP analysis of benign, low malignant potential and low grade ovarian serous tumours.Identifying and targeting ROS1 gene fusions in non-small cell lung cancer.Current concepts on the molecular pathology of non-small cell lung carcinoma.Molecular pathways: ROS1 fusion proteins in cancer.Specific visualization and identification of phosphoproteome in gels.Mouse model for ROS1-rearranged lung cancer Missense variants of uncertain significance (VUS) altering the phosphorylation patterns of BRCA1 and BRCA2.

P2860

Q24292901-C4EE5A84-C134-4988-873D-4B36F5815D16 Q24303065-45903184-6CAD-467B-8557-DF244226D9FC Q24337500-1F1671BA-27AD-43DD-A1FB-98A5E4EDD235 Q24604831-F2D3FA1E-D84D-4310-BE32-41667AFFE6DE Q24619841-E0F481BA-CC8A-40D5-9795-AEC040CF2D50 Q24630466-2CAB1704-87BF-4573-B2A8-79007AD8C552 Q26739942-116F0B91-E449-42F9-AD19-B5D496966F21 Q26751157-7D18768E-FFE5-430B-B426-993227EAFC0A Q26751224-AE3521F6-EF89-46E0-94E3-043641DECF8E Q26751655-97280378-AE41-49F6-A89C-C3672A631BE0 Q26768158-7CB630A1-60D3-48E5-8A5B-D5F3E535032D Q26775347-8A3A392F-EAEC-4149-B118-651A68EC2CB9 Q26798369-E40CAD8E-80C5-4196-AC71-DB95821874B9 Q26851392-964159BE-1F67-40BC-B9DE-DDB15BD84F13 Q26851636-9C942F00-3837-4C88-9075-EEDE76BAAFFF Q26859368-816F2AA0-B9C5-4A7A-96C2-F0B45785370C Q27675641-272E5EB6-4394-47B8-BFAD-63A3E4104C2A Q27851700-8EB1343C-F6FB-4C46-903B-44FC20372224 Q27852699-D4ED0DED-1309-4411-AB24-14D7FA2EBE27 Q27852856-2466573D-4FD0-4157-8C3E-C3D29E4C20D4 Q27853075-5D35914F-0AD9-43B2-A214-4DBCC3ABBC1F Q27853138-D38B86FE-EFC0-42F9-B79A-BD3C5947694F Q28271194-C75A280C-665C-4191-9DEA-3325E3422222 Q28293851-EB869F3B-F6C0-4970-AE7A-17620ED8FF5A Q28486949-8C5738CD-61B7-41EB-9405-A3DF3DE6BEDE Q29617292-3157DBBC-0789-48D9-934B-A410D72F292B Q33593910-F7A23887-B5AB-4C0B-9BE0-EB8733DE5342 Q33621529-BA50ABFE-B7FC-46D2-B42C-4D5F8768A350 Q33828898-C1989A2E-05D3-4826-A275-587326948912 Q33854847-74A4A3EF-8A8F-4280-9AB5-95587CA092B3 Q33863341-8E6651A7-5554-447A-A2C7-73E616E8936D Q33911863-6DE91AE1-6ACA-4565-8795-93D05E9883D7 Q34023414-90A1FC51-8938-400E-A570-FE59BF78B0A9 Q34097804-907854EE-3576-421D-8E6B-4F627D0F9FF0 Q34295696-15909E06-FC02-4AE9-A827-B4C479B394E5 Q34310062-0B96E565-4D83-497A-B5A7-BF05FC5C8F26 Q34347504-6AA3213B-28B7-404F-85EE-F2669F183A09 Q34434079-AD008896-C64F-449B-9C43-85A87D919C8D Q34589721-91CC9DC3-F688-4EC8-9617-F145E00839A6 Q34737253-3A339152-BD6B-4F48-9DC0-85F9D525AAF3

P2860

Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma

http://www.wikidata.org/entity/Q33799157

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma

@ast

Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma

@en

type

label

Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma

@ast

Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma

@en

prefLabel

Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma

@ast

Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma

@en

P1433

Q33799157-9A065C92-3BC8-478E-9F8B-AB913999E01C

P1476

Q33799157-1D9707A8-8357-4300-A163-15A810151710

P2093

Q33799157-02DC555B-5B07-412C-9F2A-602AE8FF8D69

Q33799157-049AD070-8F17-4073-9D10-A41ECA93BFD9

Q33799157-061D8E22-C12F-4633-9390-C09F30F16DB4

Q33799157-09157066-0E05-4EFC-AF2A-BCE272B12482

Q33799157-0C84E804-EB93-4EA2-96B4-1AD36E868433

Q33799157-0D18B257-94DF-4A32-AF67-9F61463A8C8F

Q33799157-119BD648-6360-4912-BE01-A8162A20966D

Q33799157-26E0446B-5D9E-4A4B-8860-0C5C99E1EF85

Q33799157-38EC8F62-E26C-4884-AD9B-BA35AA3AC57D

Q33799157-3D239CCC-55C4-4D1C-96B6-FDF76AB62C0A

P2860

Q33799157-01A3E77C-6AB3-4CAA-A799-0908B4B65604

Q33799157-08B9F128-BB68-46E0-A769-358F405C07FA

Q33799157-0E93C4E5-23AB-43FF-8853-729F2472AC89

Q33799157-1DDA87BF-99E8-4E81-929B-19A907AFDF4F

Q33799157-2C56144D-C9F5-4AED-A373-34F9EA38C486

Q33799157-510878B5-C187-4AD4-B15F-3A5B9247FDF0

Q33799157-538DEA30-44EB-4481-9C19-3272D712BFD1

Q33799157-6EF65BF0-6DB9-4E82-B927-D3C2DB055522

Q33799157-71590252-6E7F-4471-970B-67C5EBDBDAF1

Q33799157-76ACBB77-F6FA-49CC-A1CA-727E2B92948C

P304

Q33799157-DE9DA100-432A-4C10-BCD4-B4ED0591072C

P31

Q33799157-31461755-416B-438E-833A-9D4135D555CD

P356

Q33799157-6C189342-0557-4AFE-8F3F-B011E11E210D

P407

Q33799157-4DE3A881-95B2-4B67-8AB9-7A5AD67DAF38

P433

Q33799157-FB86E21A-2E79-441B-ADB9-ECA8F561CC90

P478

Q33799157-6C7CCE61-F3F5-406E-A669-B1025BFC8C81

P577

Q33799157-6627C913-246D-4160-9124-19362FEDEE78

P5875

Q33799157-A00C9B15-2872-4B99-A4E7-4FE6533A4CE1

P698

Q33799157-D44792D1-7E81-483A-ADA6-64EAFBB75F6B

P921

Q33799157-CBF7C261-7BD9-4E08-A739-5FEE0713AF4E

P932

Q33799157-2D61875D-F95C-4DAF-B573-1E908ABB4A54

P356

JOURNAL.PONE.0015640

P1433

P1476

Survey of tyrosine kinase sign ...... ns in human cholangiocarcinoma

@en

P2093

Baiyong Shen

http://www.w3.org/2001/XMLSchema#string

Brett Norris

http://www.w3.org/2001/XMLSchema#string

Chenghong Peng

http://www.w3.org/2001/XMLSchema#string

Chunlin Wu

http://www.w3.org/2001/XMLSchema#string

Cynthia Reeves

http://www.w3.org/2001/XMLSchema#string

Feizhou Huang

http://www.w3.org/2001/XMLSchema#string

Gang Deng

http://www.w3.org/2001/XMLSchema#string

Gregory Innocenti

http://www.w3.org/2001/XMLSchema#string

Herbert Haack

http://www.w3.org/2001/XMLSchema#string

Hongwei Li

http://www.w3.org/2001/XMLSchema#string

P2860

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells

Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6

ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice

The protein kinase complement of the human genome

Oncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastoma

A census of human cancer genes

A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia

Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21)

Oncogenic kinase signalling

Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

P304

e15640

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1371/JOURNAL.PONE.0015640

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

6

http://www.w3.org/2001/XMLSchema#string

P577

2011-01-06T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49773104

http://www.w3.org/2001/XMLSchema#string

P698

21253578

http://www.w3.org/2001/XMLSchema#string

P921

cholangiocarcinoma

P932

3017127

http://www.w3.org/2001/XMLSchema#string