p53 regulation by post-translational modification and nuclear retention in response to diverse stresses. - Wikidata - wikimedia - TriplyDB

p53 regulation by post-translational modification and nuclear retention in response to diverse stresses.

p53 regulation by post-translational modification and nuclear retention in response to diverse stresses.

http://www.wikidata.org/entity/Q33807807

about

MDM4 (MDMX) overexpression enhances stabilization of stress-induced p53 and promotes apoptosis Regulation of human p53 activity and cell localization by alternative splicing Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics Suppression of the STK15 oncogenic activity requires a transactivation-independent p53 function Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation The death substrate Gas2 binds m-calpain and increases susceptibility to p53-dependent apoptosis.Activation of p53 in cervical carcinoma cells by small molecules.New insights into the role of nuclear factor-kB in cell growth regulation The molecular fingerprint of high grade serous ovarian cancer reflects its fallopian tube origin Multiple sites of in vivo phosphorylation in the MDM2 oncoprotein cluster within two important functional domains Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA A role for Hsc70 in regulating nucleocytoplasmic transport of a temperature-sensitive p53 (p53Val-135)Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage p53/PUMA expression in human pulmonary fibroblasts mediates cell activation and migration in silicosis Simulating molecular mechanisms of the MDM2-mediated regulatory interactions: a conformational selection model of the MDM2 lid dynamics Regulation of p53 by Mdm2 E3 ligase function is dispensable in embryogenesis and development, but essential in response to DNA damage The pharmacodynamics of the p53-Mdm2 targeting drug Nutlin: the role of gene-switching noise Impacts of different exposure scenarios on transcript abundances in Danio rerio embryos when investigating the toxicological burden of riverine sediments p53 binds the nuclear matrix in normal cells: binding involves the proline-rich domain of p53 and increases following genotoxic stress.Cell cycle progression and de novo centriole assembly after centrosomal removal in untransformed human cells.Evidence for DNA damage checkpoint activation in barrett esophagus UV-B exposure causes DNA damage and changes in protein expression in northern pike (Esox lucius) posthatched embryos.Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation.Hsp70 interactions with the p53 tumour suppressor protein.The evolution of diverse biological responses to DNA damage: insights from yeast and p53.Flexible lid to the p53-binding domain of human Mdm2: implications for p53 regulation.Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2 Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study.Repression of mammary stem/progenitor cells by p53 is mediated by Notch and separable from apoptotic activity.Combined modality doxorubicin-based chemotherapy and chitosan-mediated p53 gene therapy using double-walled microspheres for treatment of human hepatocellular carcinoma Phosphorylation of Thr18 and Ser20 of p53 in Ad-p53-induced apoptosis.Inhibition of microtubule dynamics impedes repair of kidney ischemia/reperfusion injury and increases fibrosis.Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell apoptosis in normoxia and hypoxia PTEN ameliorates autoimmune arthritis through down-regulating STAT3 activation with reciprocal balance of Th17 and Tregs.4-Hydroxy TEMPO attenuates dichlorvos induced microglial activation and apoptosis Transcription factors and cognate signalling cascades in the regulation of autophagy.Lysines in the tetramerization domain of p53 selectively modulate G1 arrest Effects of Different Zinc Species on Cellar Zinc Distribution, Cell Cycle, Apoptosis and Viability in MDAMB231 Cells.

P2860

Q24301309-6EB093F6-6002-4D42-8699-F065E766396F Q24302205-02C1BB4C-F7A5-47C9-87AA-905324EE8E69 Q24533915-4E8843AD-1B6B-4757-95B6-593CA88BD553 Q24534295-C944162C-2AD5-431C-953B-B3D482549069 Q24534983-E321618B-A793-421E-9704-7F44C4A070B9 Q24535515-390BA728-5302-41F9-94ED-1F5F32F07D03 Q24644964-40A00DBF-6A8A-44CD-AAFC-C20EF991100C Q26058119-E9397CE2-1F8B-4F5C-965F-142A2B1BD87B Q27008375-B2B9A1F0-3090-4151-87DE-24D38817E042 Q28142503-DC934401-7E1B-4057-8D5A-E6FFA8066AC5 Q28200753-E029553B-52D4-4E48-AF1A-19BE9450C04C Q28211719-6BE6ECF9-A3D9-4F2B-BE9C-19792D28B3C6 Q28360922-6BF44913-3F21-4ADB-B54F-7B56030E350E Q28364113-D04B5BEC-5DE0-4A03-8223-A934DE598D3C Q28394092-69A91BC6-0E97-4B46-94E6-1697FEC29A5F Q28481334-F1F5DA2B-624A-4A2A-86C9-33F69AA04F1A Q28510160-1687F5EA-A051-44DB-A6DD-460B5853F581 Q28542661-E51800C1-1D96-4841-886C-DCF861671FE1 Q28542773-E74BFE7A-02FF-4F47-88C2-E701628E5498 Q30167909-ABD51530-553A-46DE-A6F7-A638A2438287 Q33269437-7A6C3F2B-516D-455A-823A-B320775B029B Q33655360-D7275244-7B29-4460-9161-92F94427B2B1 Q34092673-2AD31A33-EE1F-42CE-A1B5-41A9E783EBF5 Q34324710-89A00C0D-88B4-40E1-AFEE-DF4DD8327997 Q34353609-6D926FF5-B1EA-4B85-93CA-73F71583CAF8 Q34353830-B6303AF4-DC5B-4127-911D-D09FFA954F0A Q34487385-D2F2AF7F-3732-49AE-A138-14FEDA6E2D99 Q34761203-F41D60E4-ADEB-462A-A1AC-EB3D3DAAC015 Q35081240-046F0C48-70CD-4A98-BAE8-081829773767 Q35268497-1E2E385C-FED8-4883-A248-B267DA25A8A5 Q36113210-2BE0B8E0-C260-4CFB-B493-25465FCC46A9 Q36823977-1E943B41-94E7-427F-B31E-A21F17664CB2 Q36926753-841344A0-711C-4EDD-B99C-CE94ADF60F4D Q36980406-5537D16C-D887-4560-A791-D664419217CE Q37145375-6A5D53FC-9AD4-49C5-999B-60726DD56629 Q37314776-50EAC63B-BADF-42B4-A9BF-E0B885C5C831 Q37596215-E3BDC267-AFA4-456A-B136-A9112E5F734C Q38344277-29E04C9B-F861-406D-A02A-F3DFAB479C6B Q38769335-BBADD2F1-57D2-4D13-99DB-BE88F074FFA6 Q38850675-EE78CAE7-2C73-4D81-AF02-7B935D83F388

P2860

p53 regulation by post-translational modification and nuclear retention in response to diverse stresses.

http://www.wikidata.org/entity/Q33807807

description

1999 nî lūn-bûn

@nan

1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

p53 regulation by post-transla ...... response to diverse stresses.

@ast

p53 regulation by post-transla ...... response to diverse stresses.

@en

type

label

p53 regulation by post-transla ...... response to diverse stresses.

@ast

p53 regulation by post-transla ...... response to diverse stresses.

@en

prefLabel

p53 regulation by post-transla ...... response to diverse stresses.

@ast

p53 regulation by post-transla ...... response to diverse stresses.

@en

P1433

Q33807807-CF2B1887-6237-41EA-BD28-98EEA02D29F1

P1476

Q33807807-DF5626F0-CF4C-4DF8-9624-3AFDACAD2805

P2093

Q33807807-1882D0C2-FB76-4339-894C-D25BC6C628B8

Q33807807-255D28F8-AA75-4689-AF34-B8FDED06A8E6

Q33807807-DFC7B264-6B09-4BFC-920B-7B029DC14316

Q33807807-E3BDBD3B-F215-4D1C-A6CF-F55D1F7DF50A

P2860

Q33807807-000736FE-4133-4075-8F98-DDD9D693819C

Q33807807-018C005A-17E8-4A58-8C3A-B63D0981CE11

Q33807807-01984252-05AA-4C49-98C1-B52B2F957979

Q33807807-04E4D318-1194-4737-8063-0C05A6FABF54

Q33807807-06DB217C-F782-448B-A951-9E3214609036

Q33807807-06EC3F28-45ED-4BF5-A96F-177D28C694BE

Q33807807-0B4AF98E-FDF7-4006-9E1A-ED06F517B5D5

Q33807807-0BC1CDC3-4D97-4E36-BDE5-B3960D3EDBE8

Q33807807-0E8102B7-93DC-483C-93D3-DFB3250C6123

Q33807807-0F6387F6-EC9A-4404-BDBB-7C06397AA795

P2888

Q33807807-711F5BC2-88D2-47B5-95E2-AE5AD3C30D2A

P304

Q33807807-C58A3C9E-B287-422E-9724-AFA97E660EBF

P31

Q33807807-8B470925-C76A-4F88-A874-7A3170D063AD

P356

Q33807807-6635F812-7733-4D50-8A11-254CB3A993CB

P407

Q33807807-51702958-3E38-4FAE-9A2B-EBD81998D5A1

P433

Q33807807-E5ACA2F5-095D-4A04-856C-5C066CDCAEC5

P478

Q33807807-CD7800A6-227B-46B5-A70D-6113EDD6D331

P577

Q33807807-21B423C1-1A68-4398-8036-24A84056473F

P5875

Q33807807-EA331CEC-11D4-4946-AF21-6DD3EA8A4EA3

P6179

Q33807807-ECFE77D6-3C7B-40D2-9942-92627929CE8D

P698

Q33807807-8949B50C-0F00-4702-9D02-F9F976BFD9C9

P356

P1433

P1476

p53 regulation by post-transla ...... response to diverse stresses.

@en

P2093

Jimenez GS

http://www.w3.org/2001/XMLSchema#string

Khan SH

http://www.w3.org/2001/XMLSchema#string

Stommel JM

http://www.w3.org/2001/XMLSchema#string

Wahl GM

http://www.w3.org/2001/XMLSchema#string

P2860

A role for ATR in the DNA damage-induced phosphorylation of p53

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

Synergistic activation of transcription by CBP and p53

Binding and modulation of p53 by p300/CBP coactivators

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

Mdm2 promotes the rapid degradation of p53

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

P2888

P304

7656-7665

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.ONC.1203013

http://www.w3.org/2001/XMLSchema#string

P407

P433

53

http://www.w3.org/2001/XMLSchema#string

P478

18

http://www.w3.org/2001/XMLSchema#string

P577

1999-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

230858711

http://www.w3.org/2001/XMLSchema#string

P6179

1035318174

http://www.w3.org/2001/XMLSchema#string

P698

10618705

http://www.w3.org/2001/XMLSchema#string