Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells. - Wikidata - wikimedia - TriplyDB

Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.

Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.

http://www.wikidata.org/entity/Q34324710

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The Effects of CapZ Peptide (TRTK-12) Binding to S100B–Ca2+ as Examined by NMR and X-ray Crystallography Divalent Metal Ion Complexes of S100B in the Absence and Presence of Pentamidine Refinement of the solution structure and dynamic properties of Ca2+-bound rat S100B Small Molecules Bound to Unique Sites in the Target Protein Binding Cleft of Calcium-Bound S100B As Characterized by Nuclear Magnetic Resonance and X-ray Crystallography In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B Binding of transition metals to S100 proteins S100A1: Structure, Function, and Therapeutic Potential S100B Protein Regulates Astrocyte Shape and Migration via Interaction with Src Kinase: IMPLICATIONS FOR ASTROCYTE DEVELOPMENT, ACTIVATION, AND TUMOR GROWTH Complex formation between S100B protein and the p90 ribosomal S6 kinase (RSK) in malignant melanoma is calcium-dependent and inhibits extracellular signal-regulated kinase (ERK)-mediated phosphorylation of RSK The effect of pentamidine on melanoma ex vivo.Simultaneous inhibition of key growth pathways in melanoma cells and tumor regression by a designed bidentate constrained helical peptide The calcium-binding protein S100B down-regulates p53 and apoptosis in malignant melanoma.Covalent small molecule inhibitors of Ca(2+)-bound S100B.Molecular determinants of S100B oligomer formation The Nucleolus Takes Control of Protein Trafficking Under Cellular Stress.S100B attenuates microglia activation in gliomas: possible role of STAT3 pathway Expression of p53 target genes in the early phase of long-term potentiation in the rat hippocampal CA1 area S100 proteins in cancer.S100B-p53 disengagement by pentamidine promotes apoptosis and inhibits cellular migration via aquaporin-4 and metalloproteinase-2 inhibition in C6 glioma cells.Sarcophine-diol, a skin cancer chemopreventive agent, inhibits proliferation and stimulates apoptosis in mouse melanoma B₁₆F₁₀ cell line.Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations.Involvement of S100A14 protein in cell invasion by affecting expression and function of matrix metalloproteinase (MMP)-2 via p53-dependent transcriptional regulation Regulation of p53 oligomerization by Ras superfamily protein RBEL1A Molecular dynamic simulation insights into the normal state and restoration of p53 function.Target binding to S100B reduces dynamic properties and increases Ca(2+)-binding affinity for wild type and EF-hand mutant proteins.An integrative model for recurrence in ovarian cancer.Review of S100A9 biology and its role in cancer.Functions of S100 proteins.Novel protein-inhibitor interactions in site 3 of Ca(2+)-bound S100B as discovered by X-ray crystallography.In vivo screening of S100B inhibitors for melanoma therapy.S100B promotes glioma growth through chemoattraction of myeloid-derived macrophages Loss of S100 antigenicity in metastatic melanoma.The Reference Level of Serum S-100B Protein for Poor Prognosis in Patients with Intracranial Extracerebral Hematoma.MicroRNA profiling of patient plasma for clinical trials using bioinformatics and biostatistical approaches S100 protein family in human cancer.Evaluation of potential interactions between the metastasis-associated protein S100A4 and the tumor suppressor protein p53.Human bile as a rich source of biomarkers for hepatopancreatobiliary cancers.Arundic Acid Prevents Developmental Upregulation of S100B Expression and Inhibits Enteric Glial Development.S100A6 protein: functional roles.

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P2860

Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.

http://www.wikidata.org/entity/Q34324710

description

2004 nî lūn-bûn

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2004 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2004 թվականի հունիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.

@ast

Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.

@en

Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.

@nl

type

label

Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.

@ast

Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.

@en

Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.

@nl

prefLabel

Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.

@ast

Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.

@en

Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.

@nl

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Journal of Biological Chemistry

P1476

Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.

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P2093

David J Weber

http://www.w3.org/2001/XMLSchema#string

France Carrier

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Jing Lin

http://www.w3.org/2001/XMLSchema#string

Joseph Markowitz

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Paul T Wilder

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Qingyuan Yang

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Zhe Yan

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P2860

Covalent and noncovalent modifiers of the p53 protein

Structure of the negative regulatory domain of p53 bound to S100B(betabeta)

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

p53, the cellular gatekeeper for growth and division

Functions of the MDM2 oncoprotein

MDM2--master regulator of the p53 tumor suppressor protein

Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction

The S100 protein family: history, function, and expression

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

Post-translational modifications and activation of p53 by genotoxic stresses

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34071-34077

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10.1074/JBC.M405419200

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32

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279

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15178678

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