Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid - Wikidata - wikimedia - TriplyDB

Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid

Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid

http://www.wikidata.org/entity/Q33819900

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Allosteric control of an ionotropic glutamate receptor with an optical switch.Kainate receptors coming of age: milestones of two decades of research Piracetam defines a new binding site for allosteric modulators of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid Molecular mechanism of ligand recognition by NR3 subtype glutamate receptors Structure of the S1S2 glutamate binding domain of GLuR3 Correlating AMPA Receptor Activation and Cleft Closure across Subunits: Crystal Structures of the GluR4 Ligand-Binding Domain in Complex with Full and Partial Agonists †Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS Correlating efficacy and desensitization with GluK2 ligand-binding domain movements Glutamate receptor ion channels: structure, regulation, and function Novel analogs and stereoisomers of the marine toxin neodysiherbaine with specificity for kainate receptors A transmembrane accessory subunit that modulates kainate-type glutamate receptors.Domain organization and function in GluK2 subtype kainate receptors.The neurotoxin domoate causes long-lasting inhibition of the kainate receptor GluK5 subunit The biochemistry, ultrastructure, and subunit assembly mechanism of AMPA receptors.Subunit arrangement and function in NMDA receptors.Functional architecture of olfactory ionotropic glutamate receptors.Reduced curvature of ligand-binding domain free-energy surface underlies partial agonism at NMDA receptors.Conformational changes at the agonist binding domain of the N-methyl-D-aspartic acid receptor.Neurological disease rises from ocean to bring model for human epilepsy to life.Pharmacological insights obtained from structure-function studies of ionotropic glutamate receptors.Glutamate receptors and endoplasmic reticulum quality control: looking beneath the surface.Energetics of glutamate receptor ligand binding domain dimer assembly are modulated by allosteric ions.Ion-dependent gating of kainate receptors.Optochemical genetics.The role of protein N-glycosylation in neural transmission Retour aux sources: defining the structural basis of glutamate receptor activation.Vibrational spectroscopic investigation of the ligand binding domain of kainate receptors.Luminescence resonance energy transfer investigation of conformational changes in the ligand binding domain of a kainate receptor Concanavalin-A reports agonist-induced conformational changes in the intact GluR6 kainate receptor.N-glycosylation in regulation of the nervous system.In silico insights of L-glutamate: structural features in vacuum and in complex with its receptor.Crystallization and preliminary X-ray crystallographic analysis of the GluR0 ligand-binding core from Nostoc punctiforme.Molecular mechanism of parallel fiber-Purkinje cell synapse formation.Progressive changes in hippocampal cytoarchitecture in a neurodevelopmental rat model of epilepsy: implications for understanding presymptomatic epileptogenesis, predictive diagnosis, and targeted treatments.Disruption of interdomain interactions in the glutamate binding pocket affects differentially agonist affinity and efficacy of N-methyl-D-aspartate receptor activation.Rigid body essential X-ray crystallography: distinguishing the bend and twist of glutamate receptor ligand binding domains.Molecular Dynamics Investigation of gluazo, a Photo-Switchable Ligand for the Glutamate Receptor GluK2.

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P2860

Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid

http://www.wikidata.org/entity/Q33819900

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2005 nî lūn-bûn

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2005 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2005年の論文

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2005年論文

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Structure of the kainate recep ...... ain complexed with domoic acid

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Structure of the kainate recep ...... ain complexed with domoic acid

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Structure of the kainate recep ...... ain complexed with domoic acid

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Max H Nanao

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Senyon Choe

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Stephen F Heinemann

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Tim Green

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Yael Stern-Bach

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P2860

Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core

Mechanism of glutamate receptor desensitization

A mechanism of regulating transmembrane potassium flux through a ligand-mediated conformational switch

Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core

Three-dimensional structure of the ligand-binding core of GluR2 in complex with the agonist (S)-ATPA: implications for receptor subunit selectivity

Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal

Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core

Structural basis for partial agonist action at ionotropic glutamate receptors

Structure of a glutamate-receptor ligand-binding core in complex with kainate

Coot: model-building tools for molecular graphics

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